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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c69CT8Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c69CT8Cyclin-dependent kinase 22.7.11.221.000
4kd11QKCyclin-dependent kinase 22.7.11.220.600
3rahO1ZCyclin-dependent kinase 22.7.11.220.578
4fklCK2Cyclin-dependent kinase 22.7.11.220.560
1w8cN69Cyclin-dependent kinase 22.7.11.220.552
3raiX85Cyclin-dependent kinase 22.7.11.220.550
3rm719ZCyclin-dependent kinase 22.7.11.220.550
2r3fSC8Cyclin-dependent kinase 22.7.11.220.545
3r7yZ04Cyclin-dependent kinase 22.7.11.220.543
2r3r6SCCyclin-dependent kinase 22.7.11.220.533
2r3o2SCCyclin-dependent kinase 22.7.11.220.524
3iggEFQCyclin-dependent kinase 22.7.11.220.516
3r8vZ62Cyclin-dependent kinase 22.7.11.220.516
3qwjX6ACyclin-dependent kinase 22.7.11.220.513
1p2a5BNCyclin-dependent kinase 22.7.11.220.512
3qx2X63Cyclin-dependent kinase 22.7.11.220.510
2btrU73Cyclin-dependent kinase 22.7.11.220.509
2c6iDT1Cyclin-dependent kinase 22.7.11.220.509
3qtsX46Cyclin-dependent kinase 22.7.11.220.507
3r9nZ68Cyclin-dependent kinase 22.7.11.220.507
3lfsA07Cyclin-dependent kinase 22.7.11.220.505
3qzgX67Cyclin-dependent kinase 22.7.11.220.502
1b39ATPCyclin-dependent kinase 22.7.11.220.501
2c6o4SPCyclin-dependent kinase 22.7.11.220.500
2r3iSCFCyclin-dependent kinase 22.7.11.220.496
4fkpLS5Cyclin-dependent kinase 22.7.11.220.495
2r3gSC9Cyclin-dependent kinase 22.7.11.220.492
3qxoX65Cyclin-dependent kinase 22.7.11.220.492
2r3p3SCCyclin-dependent kinase 22.7.11.220.491
3r1yX76Cyclin-dependent kinase 22.7.11.220.489
1h0w207Cyclin-dependent kinase 22.7.11.220.487
1ke6LS2Cyclin-dependent kinase 22.7.11.220.487
5aniES4Cyclin-dependent kinase 22.7.11.220.487
1gz8MBPCyclin-dependent kinase 22.7.11.220.486
1ke5LS1Cyclin-dependent kinase 22.7.11.220.485
2vthLZ2Cyclin-dependent kinase 22.7.11.220.485
1b38ATPCyclin-dependent kinase 22.7.11.220.484
2c6mDT5Cyclin-dependent kinase 22.7.11.220.483
3r7vZ02Cyclin-dependent kinase 22.7.11.220.483
3r73X87Cyclin-dependent kinase 22.7.11.220.482
4fki09KCyclin-dependent kinase 22.7.11.220.482
3s2pPMUCyclin-dependent kinase 22.7.11.220.481
1e1xNW1Cyclin-dependent kinase 22.7.11.220.476
2r3mSCXCyclin-dependent kinase 22.7.11.220.475
3rpr25ZCyclin-dependent kinase 22.7.11.220.474
2c68CT6Cyclin-dependent kinase 22.7.11.220.473
3r9hZ67Cyclin-dependent kinase 22.7.11.220.471
4fkq42KCyclin-dependent kinase 22.7.11.220.470
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.468
1w0xOLOCyclin-dependent kinase 22.7.11.220.467
3r28XA0Cyclin-dependent kinase 22.7.11.220.467
4ek610KCyclin-dependent kinase 22.7.11.220.467
1h0vUN4Cyclin-dependent kinase 22.7.11.220.466
3qqkX02Cyclin-dependent kinase 22.7.11.220.466
2a4lRRCCyclin-dependent kinase 22.7.11.220.464
3fz1B98Cyclin-dependent kinase 22.7.11.220.464
2btsU32Cyclin-dependent kinase 22.7.11.220.461
3lfqA28Cyclin-dependent kinase 22.7.11.220.461
3lfnA27Cyclin-dependent kinase 22.7.11.220.460
1oitHDTCyclin-dependent kinase 22.7.11.220.459
1ykr628Cyclin-dependent kinase 22.7.11.220.458
3qqfX07Cyclin-dependent kinase 22.7.11.220.458
3roy22ZCyclin-dependent kinase 22.7.11.220.456
3r7uX96Cyclin-dependent kinase 22.7.11.220.455
2r3q5SCCyclin-dependent kinase 22.7.11.220.454
3r6xX84Cyclin-dependent kinase 22.7.11.220.454
1ckpPVBCyclin-dependent kinase 22.7.11.220.453
1pxmCK5Cyclin-dependent kinase 22.7.11.220.453
2vu3LZECyclin-dependent kinase 22.7.11.220.453
3wblPDYCyclin-dependent kinase 22.7.11.220.453
1gih1PUCyclin-dependent kinase 22.7.11.220.452
3qtuX44Cyclin-dependent kinase 22.7.11.220.451
3rk909ZCyclin-dependent kinase 22.7.11.220.451
2exmZIPCyclin-dependent kinase 22.7.11.220.449
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.449
3sqq99ZCyclin-dependent kinase 22.7.11.220.449
1di8DTQCyclin-dependent kinase 22.7.11.220.447
1y8yCT7Cyclin-dependent kinase 22.7.11.220.447
3r8uZ31Cyclin-dependent kinase 22.7.11.220.447
3rpo24ZCyclin-dependent kinase 22.7.11.220.447
3qqlX03Cyclin-dependent kinase 22.7.11.220.444
4fkt48KCyclin-dependent kinase 22.7.11.220.444
1oiqHDUCyclin-dependent kinase 22.7.11.220.443
2r3kSCQCyclin-dependent kinase 22.7.11.220.443
3ig7EFPCyclin-dependent kinase 22.7.11.220.441
3my5RFZCyclin-dependent kinase 22.7.11.220.441
1gii1PUCyclin-dependent kinase 22.7.11.220.440
2w05FRTCyclin-dependent kinase 22.7.11.220.440
2zjwREFCasein kinase II subunit alpha2.7.11.10.440
4fkg4CKCyclin-dependent kinase 22.7.11.220.440