sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2c4j	GSO	Glutathione S-transferase Mu 2	2.5.1.18

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2c4j	GSO	Glutathione S-transferase Mu 2	2.5.1.18	1.000
2f3m	GTD	Glutathione S-transferase Mu 1	2.5.1.18	0.525
3gst	GPR	Glutathione S-transferase Mu 1	2.5.1.18	0.494
1a5b	IGP	Tryptophan synthase alpha chain	/	0.480
2gst	GPS	Glutathione S-transferase Mu 1	2.5.1.18	0.467
1hnc	GDN	Glutathione S-transferase Mu 2	2.5.1.18	0.466
4q71	FAD	Bifunctional protein PutA	/	0.447
1beu	IPL	Tryptophan synthase alpha chain	/	0.446
2jn3	JN3	Fatty acid-binding protein, liver	/	0.446
4cdm	FO1	Deoxyribodipyrimidine photolyase	/	0.445
1fmj	RTL	Retinol dehydratase	/	0.443
1ml6	GBX	Glutathione S-transferase A2	2.5.1.18	0.442