sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2c3o | TPP | Pyruvate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2c3o | TPP | Pyruvate synthase | / | 1.000 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.621 | |
| 2uza | HTL | Pyruvate synthase | / | 0.616 | |
| 2pda | TPP | Pyruvate synthase | / | 0.607 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.587 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.566 | |
| 1kek | HTL | Pyruvate synthase | / | 0.545 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.511 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.465 | |
| 5doz | NDP | JamJ | / | 0.453 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.448 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.440 |