Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 1.000 | |
2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.670 | |
2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.662 | |
3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.651 | |
2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.646 | |
4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.631 | |
2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.629 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.627 | |
2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.624 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.623 | |
4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.618 | |
4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.614 | |
2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.613 | |
2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.609 | |
2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.609 | |
4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.605 | |
4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.603 | |
2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.588 | |
2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.588 | |
4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.582 | |
2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.581 | |
2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.579 | |
4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.578 | |
4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.578 | |
2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.577 | |
4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.576 | |
2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.575 | |
2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.574 | |
2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.569 | |
3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.569 | |
4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.569 | |
2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.568 | |
2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.567 | |
2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.567 | |
2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.565 | |
4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.565 | |
2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.563 | |
2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.560 | |
2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.560 | |
4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.559 | |
2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.557 | |
3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.555 | |
2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.553 | |
5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.551 | |
2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.550 | |
3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.550 | |
4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.550 | |
2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.549 | |
2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.548 | |
2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.547 | |
2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.547 | |
4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.546 | |
1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.545 | |
3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.543 | |
1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.542 | |
4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.541 | |
2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.540 | |
2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.539 | |
4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.539 | |
4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.538 | |
4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.536 | |
2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.535 | |
2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.535 | |
4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.535 | |
4fta | H5K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.535 | |
3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.534 | |
3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.532 | |
2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.531 | |
1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.526 | |
2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.526 | |
3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.526 | |
4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.526 | |
2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.525 | |
4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.524 | |
1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.522 | |
2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.521 | |
2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.520 | |
3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.520 | |
1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.519 | |
4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.519 | |
2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.518 | |
3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.518 | |
4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.517 | |
4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.517 | |
1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.516 | |
2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.516 | |
3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.514 | |
2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.513 | |
1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.511 | |
2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.511 | |
2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.510 | |
4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.509 | |
4jik | 1KO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.508 | |
2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.507 | |
4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.506 | |
2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.505 | |
3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.505 | |
4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.505 | |
1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.504 | |
2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.503 | |
2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.503 | |
4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.503 | |
1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.502 | |
4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.502 | |
4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.501 | |
4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.501 | |
1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.500 | |
4fto | 3HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.500 | |
2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.499 | |
2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.499 | |
4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.499 | |
4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.498 | |
1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.497 | |
4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.497 | |
2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.496 | |
3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.495 | |
4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.495 | |
4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.495 | |
5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.495 | |
2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.494 | |
3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.494 | |
4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.494 | |
2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.493 | |
2ydk | YDK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.493 | |
3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.493 | |
4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.493 | |
1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.492 | |
4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.491 | |
2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.491 | |
3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.491 | |
1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.489 | |
3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.489 | |
4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.489 | |
2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.488 | |
4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.488 | |
3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.487 | |
3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.487 | |
2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.486 | |
4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.486 | |
4l9i | 8PR | Rhodopsin kinase | / | 0.486 | |
2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.484 | |
3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.484 | |
4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.484 | |
5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.484 | |
2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.483 | |
2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.483 | |
2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.483 | |
4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.483 | |
4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.483 | |
4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.482 | |
2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.481 | |
3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.481 | |
3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.481 | |
3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.479 | |
1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.478 | |
3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.478 | |
4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.478 | |
2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.477 | |
1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.476 | |
4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.476 | |
1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.475 | |
3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.475 | |
3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.475 | |
3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.474 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.473 | |
3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.473 | |
1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.472 | |
2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.472 | |
3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.471 | |
4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.471 | |
4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
1jkl | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.470 | |
1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.470 | |
2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.470 | |
2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.470 | |
4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.470 | |
4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.470 | |
4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.470 | |
4y93 | 746 | Tyrosine-protein kinase | / | 0.470 | |
2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.469 | |
3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.469 | |
3t8o | ATP | Rhodopsin kinase | / | 0.469 | |
4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.469 | |
2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.468 | |
2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.467 | |
4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.467 | |
4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.467 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.467 | |
3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.466 | |
4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.466 | |
1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.465 | |
2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.465 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.465 | |
2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.465 | |
3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.465 | |
2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.464 | |
4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.464 | |
1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.463 | |
5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.463 | |
2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.462 | |
4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.461 | |
2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.461 | |
3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.461 | |
4w9w | YDJ | BMP-2-inducible protein kinase | 2.7.11.1 | 0.461 | |
1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.460 | |
3ztx | ZTX | Aurora kinase B-A | 2.7.11.1 | 0.460 | |
4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.460 | |
4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.460 | |
4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.460 | |
2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.459 | |
3bqr | 4RB | Death-associated protein kinase 3 | / | 0.459 | |
3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
4e93 | GUI | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.459 | |
4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.459 | |
4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
1mqb | ANP | Ephrin type-A receptor 2 | 2.7.10.1 | 0.458 | |
1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.458 | |
1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.458 | |
2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.458 | |
2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.458 | |
3c4x | ATP | Rhodopsin kinase | / | 0.458 | |
3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.458 | |
1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.457 | |
2c4g | 514 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.457 | |
4d58 | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.457 | |
4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.457 | |
1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.456 | |
4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.456 | |
4y95 | 746 | Tyrosine-protein kinase | / | 0.456 | |
2vgp | AD6 | Aurora kinase B-A | 2.7.11.1 | 0.455 | |
2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.455 | |
2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.453 | |
2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.453 | |
3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.453 | |
4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.453 | |
1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.452 | |
3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.452 | |
3pvu | QRW | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.452 | |
3pvw | QRX | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.452 | |
3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.452 | |
2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.451 | |
3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.451 | |
3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
4a9u | A9U | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.451 | |
4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.451 | |
1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
2vrx | 447 | Aurora kinase B-A | 2.7.11.1 | 0.450 | |
2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
4ek6 | 10K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
1pkg | ADP | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.449 | |
2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.449 | |
3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.449 | |
3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
3g70 | A5T | Renin | 3.4.23.15 | 0.448 | |
3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.448 | |
4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.448 | |
4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
4wbo | ANW | Rhodopsin kinase | / | 0.448 | |
5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
5av4 | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.446 | |
3cty | FAD | Probable thioredoxin reductase | / | 0.446 | |
3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.446 | |
1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.445 | |
3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.445 | |
3krw | BA1 | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.445 | |
3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.444 | |
3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
4d4s | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.444 | |
4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.444 | |
1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
1ke5 | LS1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
2oji | 33A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
3zrk | ZRK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
4c61 | LMM | Tyrosine-protein kinase JAK2 | / | 0.442 | |
4ccb | OFG | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.442 | |
1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.441 | |
2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.441 | |
2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.441 | |
4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
2cn8 | DBQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.440 | |
5auz | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 |