Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2byc | FMN | Blue-light receptor of the BLUF-family |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 1.000 | |
| 2hfn | FMN | Activator of photopigment and puc expression | / | 0.595 | |
| 2hfo | FMN | Activator of photopigment and puc expression | / | 0.563 | |
| 3gg0 | FMN | Uncharacterized protein | / | 0.556 | |
| 3gfx | FMN | Uncharacterized protein | / | 0.539 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.538 | |
| 3gg1 | FMN | Uncharacterized protein | / | 0.532 | |
| 1x0p | FAD | Tll0078 protein | / | 0.531 | |
| 1yrx | FMN | AppA protein | / | 0.528 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.513 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.511 | |
| 3mzi | FMN | Activator of photopigment and puc expression | / | 0.511 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.495 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.494 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
| 2nli | FMN | Lactate oxidase | / | 0.491 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.487 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.486 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.486 | |
| 4hh0 | FMN | AppA protein | / | 0.483 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.481 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.480 | |
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 | / | 0.479 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.478 | |
| 2kb2 | FMN | Uncharacterized protein | / | 0.476 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
| 1lp6 | C5P | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.475 | |
| 4lb2 | DM5 | Serum albumin | / | 0.475 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.472 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.472 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.472 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.471 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.471 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.470 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.470 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.470 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.469 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.468 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.468 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.468 | |
| 5bpf | ADP | D-alanine--D-alanine ligase | / | 0.468 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.467 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.466 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3pls | ANP | Macrophage-stimulating protein receptor | 2.7.10.1 | 0.465 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 2ixa | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.464 | |
| 2ohx | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.464 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.464 | |
| 4y0x | ADP | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.464 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.463 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.463 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.462 | |
| 5cds | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.461 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.461 | |
| 2p55 | MRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.461 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.461 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.461 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.461 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.461 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.461 | |
| 4yut | FMN | Family 3 adenylate cyclase | / | 0.461 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.461 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.460 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.460 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.460 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.460 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.460 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.459 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.459 | |
| 2c4g | 514 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.459 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 5ahw | CMP | Universal stress protein family protein, putative | / | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase | / | 0.458 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.457 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.457 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3sfu | RBV | Polyprotein | / | 0.457 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.457 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.457 | |
| 4d2c | ALA_PHE | Di-or tripeptide:H+ symporter | / | 0.457 | |
| 5auz | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.456 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.456 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 1ef3 | NAP | Aldose reductase | 1.1.1.21 | 0.455 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.455 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.455 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.455 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.455 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.454 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.454 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.454 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4lj7 | MNT | Chaperone protein ClpB | / | 0.454 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.453 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.453 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.453 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.453 | |
| 3zy6 | GFB | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.453 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.453 | |
| 4xzm | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.453 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.452 | |
| 1x31 | FMN | Subunit alpha of sarocosine oxidase | / | 0.452 | |
| 1x31 | FMN | Subunit beta of sarcosine oxidase | / | 0.452 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 4fkq | 42K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4i4e | 1BQ | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.452 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2uyi | ADP | Kinesin-like protein KIF11 | / | 0.451 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.451 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3r1q | X75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.451 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4a9u | A9U | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 4c5b | ADP | D-alanine--D-alanine ligase B | 6.3.2.4 | 0.451 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.451 | |
| 4fz7 | 0VH | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.450 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1rag | CTP | Aspartate carbamoyltransferase regulatory chain | / | 0.450 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.450 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.450 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.450 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.450 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.449 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 3a8t | ATP | Adenylate isopentenyltransferase | / | 0.449 | |
| 3bea | IXH | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.449 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.449 | |
| 3vn9 | ANK | Dual specificity mitogen-activated protein kinase kinase 6 | 2.7.12.2 | 0.449 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.449 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.449 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.449 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.449 | |
| 5ioq | DUR | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.449 | |
| 5l8j | ADP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.448 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.448 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.448 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 1kol | NAD | Glutathione-independent formaldehyde dehydrogenase | / | 0.447 | |
| 1l7e | NAI | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
| 2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3qqf | X07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.447 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.447 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.447 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.447 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.446 | |
| 1t02 | LVA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.446 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.446 | |
| 3i64 | DNA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.446 | |
| 3t54 | ATP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.446 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.446 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.445 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.445 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 2vqs | BVD | Deoxynucleoside kinase | / | 0.445 | |
| 3n4m | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3v01 | 3V0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 5cb4 | ACP | Tubulin tyrosine ligase | / | 0.445 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.444 | |
| 1gqt | ACP | Ribokinase | / | 0.444 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.444 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2plm | SIB | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | 3.5.4.28 | 0.444 | |
| 2vkd | UPG | Cytotoxin L | / | 0.444 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.444 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.444 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.444 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.444 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.443 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.443 | |
| 1t9b | 1CS | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.443 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 3q5i | ANP | Protein kinase, putative | / | 0.443 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3u78 | E67 | Lysine-specific demethylase 7A | 1.14.11 | 0.443 | |
| 3uvr | 06F | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4lrg | 1XB | Bromodomain-containing protein 4 | / | 0.443 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.443 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.442 | |
| 2b5v | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.442 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.442 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.442 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.442 | |
| 4mb2 | ATP | Uncharacterized protein | / | 0.442 | |
| 4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 4rph | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.442 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 1jr8 | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.441 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2dvm | NAD | 439aa long hypothetical malate oxidoreductase (NAD) [malic enzyme] | / | 0.441 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.441 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.441 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3rpy | 27Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.441 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.441 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 4d58 | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4men | 25K | Bromodomain-containing protein 4 | / | 0.441 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.441 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1b39 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.440 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.440 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.440 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.440 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.440 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.440 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.440 | |
| 2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.440 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.440 | |
| 3arv | SAU | Chitinase A | / | 0.440 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.440 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.440 | |
| 3nwy | GTP | Uridylate kinase | / | 0.440 | |
| 3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.440 | |
| 3vgl | ANP | Glucokinase | / | 0.440 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.440 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.440 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4j6i | 1JV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 4yxs | EMU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.440 |