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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2btsU32Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2btsU32Cyclin-dependent kinase 22.7.11.221.000
1ke5LS1Cyclin-dependent kinase 22.7.11.220.554
1pxoCK7Cyclin-dependent kinase 22.7.11.220.543
4bgh3I6Cyclin-dependent kinase 22.7.11.220.535
2w05FRTCyclin-dependent kinase 22.7.11.220.534
3s1h56ZCyclin-dependent kinase 22.7.11.220.533
3qzgX67Cyclin-dependent kinase 22.7.11.220.528
4fkpLS5Cyclin-dependent kinase 22.7.11.220.526
2btrU73Cyclin-dependent kinase 22.7.11.220.525
3ezvEZVCyclin-dependent kinase 22.7.11.220.525
1oitHDTCyclin-dependent kinase 22.7.11.220.520
1ke7LS3Cyclin-dependent kinase 22.7.11.220.515
2c6o4SPCyclin-dependent kinase 22.7.11.220.515
1p2a5BNCyclin-dependent kinase 22.7.11.220.514
1pxmCK5Cyclin-dependent kinase 22.7.11.220.514
3qtuX44Cyclin-dependent kinase 22.7.11.220.513
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.510
3s2pPMUCyclin-dependent kinase 22.7.11.220.504
1di8DTQCyclin-dependent kinase 22.7.11.220.501
1w0xOLOCyclin-dependent kinase 22.7.11.220.501
2vu3LZECyclin-dependent kinase 22.7.11.220.501
3r7yZ04Cyclin-dependent kinase 22.7.11.220.501
3rpv26ZCyclin-dependent kinase 22.7.11.220.501
3r1sX73Cyclin-dependent kinase 22.7.11.220.500
3rak03ZCyclin-dependent kinase 22.7.11.220.500
4fki09KCyclin-dependent kinase 22.7.11.220.500
2w06FRVCyclin-dependent kinase 22.7.11.220.499
3sqq99ZCyclin-dependent kinase 22.7.11.220.498
2vv9IM9Cyclin-dependent kinase 22.7.11.220.497
3qxoX65Cyclin-dependent kinase 22.7.11.220.497
3r9dX6BCyclin-dependent kinase 22.7.11.220.497
4ek610KCyclin-dependent kinase 22.7.11.220.497
4fkq42KCyclin-dependent kinase 22.7.11.220.497
3qxpX64Cyclin-dependent kinase 22.7.11.220.496
2fvdLIACyclin-dependent kinase 22.7.11.220.495
3lfnA27Cyclin-dependent kinase 22.7.11.220.493
2uzoC62Cyclin-dependent kinase 22.7.11.220.492
1ke6LS2Cyclin-dependent kinase 22.7.11.220.491
3r8lZ30Cyclin-dependent kinase 22.7.11.220.491
4fkt48KCyclin-dependent kinase 22.7.11.220.491
1v1k3FPCyclin-dependent kinase 22.7.11.220.490
3lfqA28Cyclin-dependent kinase 22.7.11.220.490
1gii1PUCyclin-dependent kinase 22.7.11.220.489
4fkv61KCyclin-dependent kinase 22.7.11.220.489
2a4lRRCCyclin-dependent kinase 22.7.11.220.488
3qtzX42Cyclin-dependent kinase 22.7.11.220.487
1g5sI17Cyclin-dependent kinase 22.7.11.220.485
2vttLZDCyclin-dependent kinase 22.7.11.220.485
3sw719KCyclin-dependent kinase 22.7.11.220.485
1w8cN69Cyclin-dependent kinase 22.7.11.220.484
4bcmT7ZCyclin-dependent kinase 22.7.11.220.484
1r78FMDCyclin-dependent kinase 22.7.11.220.482
1y91CT9Cyclin-dependent kinase 22.7.11.220.482
1b38ATPCyclin-dependent kinase 22.7.11.220.481
1oirHDYCyclin-dependent kinase 22.7.11.220.481
3r83Z14Cyclin-dependent kinase 22.7.11.220.480
4ek816KCyclin-dependent kinase 22.7.11.220.480
1b39ATPCyclin-dependent kinase 22.7.11.220.479
3rpy27ZCyclin-dependent kinase 22.7.11.220.479
1gih1PUCyclin-dependent kinase 22.7.11.220.478
3rm719ZCyclin-dependent kinase 22.7.11.220.478
1h0w207Cyclin-dependent kinase 22.7.11.220.477
1ykr628Cyclin-dependent kinase 22.7.11.220.477
3qu0X40Cyclin-dependent kinase 22.7.11.220.476
4acm7YGCyclin-dependent kinase 22.7.11.220.476
1ckpPVBCyclin-dependent kinase 22.7.11.220.475
1ke8LS4Cyclin-dependent kinase 22.7.11.220.475
1fvv107Cyclin-dependent kinase 22.7.11.220.474
2iw94SPCyclin-dependent kinase 22.7.11.220.474
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.474
3iggEFQCyclin-dependent kinase 22.7.11.220.474
3rmf20ZCyclin-dependent kinase 22.7.11.220.473
2vthLZ2Cyclin-dependent kinase 22.7.11.220.472
2xmyCDKCyclin-dependent kinase 22.7.11.220.472
3qwjX6ACyclin-dependent kinase 22.7.11.220.472
4fkj11KCyclin-dependent kinase 22.7.11.220.472
4dgnLU2Casein kinase II subunit alpha2.7.11.10.471
2r64740Cyclin-dependent kinase 22.7.11.220.470
1urwI1PCyclin-dependent kinase 22.7.11.220.469
2iw84SPCyclin-dependent kinase 22.7.11.220.469
3rkb12ZCyclin-dependent kinase 22.7.11.220.469
1h1r6CPCyclin-dependent kinase 22.7.11.220.468
3rk708ZCyclin-dependent kinase 22.7.11.220.468
3sw418KCyclin-dependent kinase 22.7.11.220.468
2a0cCK9Cyclin-dependent kinase 22.7.11.220.467
2w17I19Cyclin-dependent kinase 22.7.11.220.466
1pyePM1Cyclin-dependent kinase 22.7.11.220.465
2c6lDT4Cyclin-dependent kinase 22.7.11.220.465
1hckATPCyclin-dependent kinase 22.7.11.220.464
3r1yX76Cyclin-dependent kinase 22.7.11.220.464
3ral04ZCyclin-dependent kinase 22.7.11.220.464
1h1s4SPCyclin-dependent kinase 22.7.11.220.463
3qtxX43Cyclin-dependent kinase 22.7.11.220.463
3raiX85Cyclin-dependent kinase 22.7.11.220.463
4fko20KCyclin-dependent kinase 22.7.11.220.463
1oguST8Cyclin-dependent kinase 22.7.11.220.462
2duv371Cyclin-dependent kinase 22.7.11.220.462
1oiyN41Cyclin-dependent kinase 22.7.11.220.461
3qqkX02Cyclin-dependent kinase 22.7.11.220.460
3roy22ZCyclin-dependent kinase 22.7.11.220.460
4fkg4CKCyclin-dependent kinase 22.7.11.220.460
2b52D42Cyclin-dependent kinase 22.7.11.220.459
2c6iDT1Cyclin-dependent kinase 22.7.11.220.459
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.459
3qqlX03Cyclin-dependent kinase 22.7.11.220.459
4anmWULCasein kinase II subunit alpha2.7.11.10.459
2r3r6SCCyclin-dependent kinase 22.7.11.220.458
3rjc06ZCyclin-dependent kinase 22.7.11.220.458
3rk909ZCyclin-dependent kinase 22.7.11.220.458
1ke9LS5Cyclin-dependent kinase 22.7.11.220.457
2uznC96Cyclin-dependent kinase 22.7.11.220.457
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.457
1vyzN5BCyclin-dependent kinase 22.7.11.220.454
3r73X87Cyclin-dependent kinase 22.7.11.220.454
3fz1B98Cyclin-dependent kinase 22.7.11.220.453
3r71X86Cyclin-dependent kinase 22.7.11.220.453
3wblPDYCyclin-dependent kinase 22.7.11.220.453
4fkr45KCyclin-dependent kinase 22.7.11.220.452
1pxpCK8Cyclin-dependent kinase 22.7.11.220.451
3r9hZ67Cyclin-dependent kinase 22.7.11.220.450
3rni21ZCyclin-dependent kinase 22.7.11.220.450
3unk0BYCyclin-dependent kinase 22.7.11.220.450
4ez30S0Cyclin-dependent kinase 22.7.11.220.450
3rm618ZCyclin-dependent kinase 22.7.11.220.449
4fx360KCyclin-dependent kinase 22.7.11.220.449
2r3iSCFCyclin-dependent kinase 22.7.11.220.448
2w1hL0FCyclin-dependent kinase 22.7.11.220.448
3be9P04Casein kinase II subunit alpha2.7.11.10.447
3qzhX69Cyclin-dependent kinase 22.7.11.220.447
4eon1ROCyclin-dependent kinase 22.7.11.220.447
4lyn1YGCyclin-dependent kinase 22.7.11.220.447
1oi9N20Cyclin-dependent kinase 22.7.11.220.446
1qmzATPCyclin-dependent kinase 22.7.11.220.446
2r3lSCWCyclin-dependent kinase 22.7.11.220.446
2uzbC75Cyclin-dependent kinase 22.7.11.220.446
4bcpT3CCyclin-dependent kinase 22.7.11.220.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
1pxlCK4Cyclin-dependent kinase 22.7.11.220.445
4eor4SPCyclin-dependent kinase 22.7.11.220.445
2pvlP55Casein kinase II subunit alpha2.7.11.10.444
4dgmAGICasein kinase II subunit alpha2.7.11.10.444
1aq1STUCyclin-dependent kinase 22.7.11.220.443
2bhhRYUCyclin-dependent kinase 22.7.11.220.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
3r7vZ02Cyclin-dependent kinase 22.7.11.220.443
2pvhP19Casein kinase II subunit alpha2.7.11.10.442
3ddpRC8Cyclin-dependent kinase 22.7.11.220.441
3r28XA0Cyclin-dependent kinase 22.7.11.220.441
3rk507ZCyclin-dependent kinase 22.7.11.220.441
3unj0BXCyclin-dependent kinase 22.7.11.220.441
1e1xNW1Cyclin-dependent kinase 22.7.11.220.440
2b55D31Cyclin-dependent kinase 22.7.11.220.440
3my5RFZCyclin-dependent kinase 22.7.11.220.440
3nux3NVCyclin-dependent kinase 62.7.11.220.440
3rpo24ZCyclin-dependent kinase 22.7.11.220.440