sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bto | GTP | Tubulin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2bto | GTP | Tubulin | / | 1.000 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.481 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.481 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.474 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 4ei7 | GDP | Plasmid replication protein RepX | / | 0.446 | |
| 3a1e | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.445 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.441 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.441 |