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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bsmBSMHeat shock protein HSP 90-alpha

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2bsmBSMHeat shock protein HSP 90-alpha/1.000
2uwd2GGHeat shock protein HSP 90-alpha/0.646
2yecXQ0Heat shock protein HSP 90-alpha/0.642
2wi5ZZ5Heat shock protein HSP 90-alpha/0.603
2vci2GJHeat shock protein HSP 90-alpha/0.597
2ye42FYHeat shock protein HSP 90-alpha/0.588
2wi1ZZ2Heat shock protein HSP 90-alpha/0.587
2yi66QMHeat shock protein HSP 90-alpha/0.579
4fcq2N6Heat shock protein HSP 90-alpha/0.577
2vcj2EQHeat shock protein HSP 90-alpha/0.571
4egh0OYHeat shock protein HSP 90-alpha/0.545
2yi7BZ8Heat shock protein HSP 90-alpha/0.512
2cct2E1Heat shock protein HSP 90-alpha/0.511
2ye92D4Heat shock protein HSP 90-alpha/0.496
2yjwYJWHeat shock protein HSP 90-alpha/0.492
2ccu2D9Heat shock protein HSP 90-alpha/0.489
3hyz42CHeat shock protein HSP 90-alpha/0.489
3omuIBDHeat shock protein 83/0.482
4egkRDCHeat shock protein HSP 90-alpha/0.482
2qg0A94Heat shock protein HSP 90-alpha/0.475
3opdHIEHeat shock protein 83/0.467
3vhaVHAHeat shock protein HSP 90-alpha/0.466
3ft5MO8Heat shock protein HSP 90-alpha/0.461
4ipeANPTNF receptor-associated protein 1/0.458
1yc14BCHeat shock protein HSP 90-alpha/0.454
4jqlVJ6Heat shock protein HSP 90-alpha/0.454
2yegXQGHeat shock protein HSP 90-alpha/0.453
1yc34BCHeat shock protein HSP 90-alpha/0.450
1osfKOSHeat shock protein HSP 90-alpha/0.448
1yetGDMHeat shock protein HSP 90-alpha/0.448
1yc443PHeat shock protein HSP 90-alpha/0.446
2wi2ZZ3Heat shock protein HSP 90-alpha/0.444
4ivgANPTNF receptor-associated protein 1/0.444