sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bnp | MST | Reaction center protein L chain |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2bnp | MST | Reaction center protein L chain | / | 1.000 | |
| 2bns | MST | Reaction center protein L chain | / | 0.695 | |
| 3g7f | UQ1 | Reaction center protein L chain | / | 0.596 | |
| 4tqq | UQ1 | Reaction center protein L chain | / | 0.591 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.578 | |
| 2i5n | UQ1 | Reaction center protein L chain | / | 0.566 | |
| 1dxr | MST | Reaction center protein L chain | / | 0.542 | |
| 6prc | CEB | Reaction center protein L chain | / | 0.528 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.523 | |
| 7prc | CET | Reaction center protein L chain | / | 0.516 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.513 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.512 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.512 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.511 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.510 | |
| 5prc | ATZ | Reaction center protein L chain | / | 0.509 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.508 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.508 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.505 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.504 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.502 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.501 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.500 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.499 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.498 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.498 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.497 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.496 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.496 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.495 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.494 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.493 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.493 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.492 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.492 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.492 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.491 | |
| 4l8u | 9AZ | Serum albumin | / | 0.490 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.489 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.489 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.487 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.487 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.487 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.486 | |
| 4pd6 | URI | Nucleoside permease | / | 0.486 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2p15 | EZT | Estrogen receptor | / | 0.485 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.485 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.485 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.484 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.484 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1osv | CHC | Bile acid receptor | / | 0.483 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.483 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.483 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.482 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.482 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.482 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.482 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.481 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.481 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.481 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.480 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.480 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.480 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.480 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.479 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.479 | |
| 4lb2 | DM5 | Serum albumin | / | 0.479 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.478 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.478 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.478 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.477 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.477 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.477 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.477 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.477 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.476 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.476 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.476 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.476 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.476 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.476 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.475 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.475 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.475 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.475 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.475 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.474 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.474 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.474 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.474 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.474 | |
| 4phu | 2YB | Free fatty acid receptor 1 | / | 0.474 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.473 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.473 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.473 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.473 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.472 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.472 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.472 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.472 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.472 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.472 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.472 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.472 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.472 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.472 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.471 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.471 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.471 | |
| 4b1f | KRH | Glutamate racemase | / | 0.471 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.471 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.470 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.470 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.470 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.469 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.469 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.469 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.469 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.469 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.469 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.468 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.468 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.468 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.468 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.467 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.467 | |
| 1p7t | ACO | Malate synthase G | / | 0.467 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.467 | |
| 2j5s | KTA | Alr4455 protein | / | 0.467 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.467 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.467 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 3up3 | XCA | aceDAF-12 | / | 0.467 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.467 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.467 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.466 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.466 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3fnu | 006 | HAP protein | / | 0.466 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.466 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.466 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.466 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.466 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.466 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.466 | |
| 1e7a | PFL | Serum albumin | / | 0.465 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.465 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.465 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.465 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.465 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.465 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.465 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.464 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 4f6v | ZYM | Dehydrosqualene synthase | / | 0.464 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.464 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.464 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.463 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3ukr | CKH | Actin-related protein 3 | / | 0.463 | |
| 3ukr | CKH | Actin-related protein 2 | / | 0.463 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.463 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.463 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.463 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.462 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.462 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.462 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.462 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3p9t | TCL | Repressor | / | 0.462 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.462 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.462 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.462 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.462 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.461 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.461 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.461 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.461 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.461 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.461 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.461 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.461 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.461 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.461 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.461 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.460 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.460 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.460 | |
| 2npf | MOU | Elongation factor 2 | / | 0.460 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.460 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.460 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.460 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4l9q | 9TP | Serum albumin | / | 0.460 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.460 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.460 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.460 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.460 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.460 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.459 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.459 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.459 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.459 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.459 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.459 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.459 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.459 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.458 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2d3u | CCT | Polyprotein | / | 0.458 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.458 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.458 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2won | ZZE | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.458 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.458 | |
| 3up0 | D7S | aceDAF-12 | / | 0.458 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.458 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.458 | |
| 4inb | 1F6 | Gag protein | / | 0.458 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.458 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.458 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.458 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1hk4 | T44 | Serum albumin | / | 0.457 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 1sqv | UHD | Cytochrome b | / | 0.457 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.457 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.457 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.457 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.457 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.457 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.457 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.457 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.457 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.457 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.457 | |
| 1ezv | SMA | Cytochrome b | / | 0.456 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.456 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.456 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.456 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.456 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.456 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.456 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.456 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.456 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.456 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.455 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.455 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.455 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.455 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.455 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.455 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.455 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.455 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.455 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.455 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.455 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.454 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.454 | |
| 3di6 | PDZ | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.454 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3l70 | JZV | Cytochrome b | / | 0.454 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.454 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.454 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.454 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.454 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.454 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.454 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.453 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.453 | |
| 2d52 | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.453 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.453 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.453 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 3kk6 | CEL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.453 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.453 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.453 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.453 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.453 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.452 | |
| 1kb9 | SMA | Cytochrome b | / | 0.452 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1qin | GIP | Lactoylglutathione lyase | 4.4.1.5 | 0.452 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.452 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.452 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.452 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.452 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.452 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4i5h | G17 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.452 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 4ph9 | IBP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.452 | |
| 4qpz | TPP | Benzaldehyde lyase | / | 0.452 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.452 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.452 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.452 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.452 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.451 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.451 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.451 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.451 | |
| 2ibz | SMA | Cytochrome b | / | 0.451 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.451 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.451 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.451 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.451 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.451 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.451 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.451 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.451 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.451 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.451 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.451 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.451 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.450 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 2bx8 | AZQ | Serum albumin | / | 0.450 | |
| 2bxo | OPB | Serum albumin | / | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.450 | |
| 2imk | GTX | AGAP009194-PA | / | 0.450 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.450 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.450 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4kot | CE3 | Uncharacterized protein | / | 0.450 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.450 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.449 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.449 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2acw | UPG | Glycosyltransferase | / | 0.449 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.449 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.449 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.449 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3htj | ET | EbrA repressor | / | 0.449 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.449 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.449 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.449 | |
| 3ldo | ANP | 78 kDa glucose-regulated protein | / | 0.449 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.449 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.449 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.449 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.449 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.449 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.448 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1khr | COA | Streptogramin A acetyltransferase | 2.3.1 | 0.448 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.448 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1o5i | NAD | 3-oxoacyl-(Acyl carrier protein) reductase | / | 0.448 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.448 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.448 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.448 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.448 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.448 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2vq5 | LDP | S-norcoclaurine synthase | / | 0.448 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.448 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.448 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.448 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.448 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.448 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.448 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.447 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.447 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.447 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.447 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.447 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.447 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.447 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.447 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.447 | |
| 2pog | WST | Estrogen receptor | / | 0.447 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.447 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.447 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.447 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.447 | |
| 3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.447 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.447 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.447 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.447 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.446 | |
| 1lrh | NLA | Auxin-binding protein 1 | / | 0.446 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.446 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.446 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2pnu | ENM | Androgen receptor | / | 0.446 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.446 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 3cne | FMN | Putative protease I | / | 0.446 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.446 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3fxu | TSU | HTH-type transcriptional regulator TsaR | / | 0.446 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.446 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.446 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.446 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.446 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.446 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4agc | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.446 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4lvt | 1XJ | Apoptosis regulator Bcl-2 | / | 0.446 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.446 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.445 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.445 | |
| 1egc | CO8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.445 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1qnf | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.445 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.445 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.445 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2yiu | SMA | Cytochrome b | / | 0.445 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.445 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.445 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.445 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4eh4 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4ju1 | 1NZ | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4kwh | NAP | Reductase homolog | / | 0.445 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.444 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.444 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.444 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.444 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2gir | NN3 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.444 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3h1j | SMA | Cytochrome b | / | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.444 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.444 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.443 | |
| 1hk2 | T44 | Serum albumin | / | 0.443 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.443 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.443 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3bhr | THG | Thymidylate synthase | / | 0.443 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.443 | |
| 3tam | M06 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.443 | |
| 3zok | NAD | 3-dehydroquinate synthase, chloroplastic | 4.2.3.4 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.442 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.442 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.442 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.442 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.442 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.442 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.442 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.442 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.442 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.442 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.442 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.442 | |
| 4a6d | SAM | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.442 | |
| 4ag8 | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.442 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.442 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.442 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.442 | |
| 4ylh | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.442 | |
| 5a3b | APR | SIR2 family protein | / | 0.442 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.442 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.442 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1jje | BYS | Beta-lactamase | / | 0.441 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.441 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1z6q | 195 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.441 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.441 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.441 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 3eel | 53T | Uncharacterized protein | / | 0.441 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.441 | |
| 3l71 | AZO | Cytochrome b | / | 0.441 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3r3d | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.441 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.441 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.441 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.441 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.441 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.441 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.441 | |
| 4nye | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.441 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.441 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.441 | |
| 5bpf | ADP | D-alanine--D-alanine ligase | / | 0.441 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.441 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.441 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.440 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.440 | |
| 1nde | MON | Estrogen receptor beta | / | 0.440 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.440 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 1zuc | T98 | Progesterone receptor | / | 0.440 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.440 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2ixb | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.440 | |
| 2oyu | IMS | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.440 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.440 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.440 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.440 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.440 | |
| 3tdl | 11D | Serum albumin | / | 0.440 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.440 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.440 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4egn | TWO | Cytochrome P450 | / | 0.440 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.440 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.440 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.440 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.440 |