Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.105

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1051.000
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.538
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.519
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.507
1k6mAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 12.7.1.1050.500
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.500
4ma4ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.494
2axnADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3/0.483
4g7gVFVLanosterol 14-alpha-demethylase/0.447
2x7hPFNProstaglandin reductase 310.442