sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 1.000 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.523 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.521 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.507 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.504 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.492 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.481 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.480 | |
| 4jxr | ACO | Acetyltransferase | / | 0.474 | |
| 3f8k | COA | Uncharacterized protein | / | 0.473 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.473 | |
| 4oae | CLM | Uncharacterized protein | / | 0.471 | |
| 4oad | CLM | Uncharacterized protein | / | 0.466 | |
| 4kub | COA | Uncharacterized protein | / | 0.464 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.462 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.461 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.458 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.457 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.457 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.456 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.455 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.452 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.451 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.450 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.449 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.449 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.447 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.446 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.441 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.440 |