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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b53D23Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2b53D23Cyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.531
3r1yX76Cyclin-dependent kinase 22.7.11.220.516
3r83Z14Cyclin-dependent kinase 22.7.11.220.513
1oirHDYCyclin-dependent kinase 22.7.11.220.495
2a0cCK9Cyclin-dependent kinase 22.7.11.220.495
3r7yZ04Cyclin-dependent kinase 22.7.11.220.490
4ek610KCyclin-dependent kinase 22.7.11.220.486
4fkt48KCyclin-dependent kinase 22.7.11.220.482
1y8yCT7Cyclin-dependent kinase 22.7.11.220.480
1pxlCK4Cyclin-dependent kinase 22.7.11.220.478
2a4lRRCCyclin-dependent kinase 22.7.11.220.477
2ds11CDCyclin-dependent kinase 22.7.11.220.477
2r3jSCJCyclin-dependent kinase 22.7.11.220.477
3r8lZ30Cyclin-dependent kinase 22.7.11.220.477
4fklCK2Cyclin-dependent kinase 22.7.11.220.477
1ykr628Cyclin-dependent kinase 22.7.11.220.475
3lfnA27Cyclin-dependent kinase 22.7.11.220.474
2w06FRVCyclin-dependent kinase 22.7.11.220.471
4fki09KCyclin-dependent kinase 22.7.11.220.469
2c6kDT2Cyclin-dependent kinase 22.7.11.220.467
2c6o4SPCyclin-dependent kinase 22.7.11.220.464
4ek816KCyclin-dependent kinase 22.7.11.220.463
3r7uX96Cyclin-dependent kinase 22.7.11.220.457
2btrU73Cyclin-dependent kinase 22.7.11.220.456
2c6lDT4Cyclin-dependent kinase 22.7.11.220.456
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.456
1pxoCK7Cyclin-dependent kinase 22.7.11.220.455
1y91CT9Cyclin-dependent kinase 22.7.11.220.453
1ke5LS1Cyclin-dependent kinase 22.7.11.220.452
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.452
1w8cN69Cyclin-dependent kinase 22.7.11.220.449
4fks46KCyclin-dependent kinase 22.7.11.220.449
3r8vZ62Cyclin-dependent kinase 22.7.11.220.448
3s2pPMUCyclin-dependent kinase 22.7.11.220.448
1w0xOLOCyclin-dependent kinase 22.7.11.220.446
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.444
4fkq42KCyclin-dependent kinase 22.7.11.220.444
1oitHDTCyclin-dependent kinase 22.7.11.220.443
2vttLZDCyclin-dependent kinase 22.7.11.220.441
3qqlX03Cyclin-dependent kinase 22.7.11.220.440
4fkg4CKCyclin-dependent kinase 22.7.11.220.440