sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 1.000 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.647 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.646 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.619 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.602 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.501 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.494 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.494 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.486 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.486 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.485 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.485 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.485 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.482 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.482 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.482 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.480 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.478 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.478 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.473 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.473 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.472 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.472 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.471 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 1osv | CHC | Bile acid receptor | / | 0.470 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.470 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.470 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.469 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.468 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.468 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.465 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.465 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.465 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.464 | |
| 1yin | CM3 | Estrogen receptor | / | 0.464 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.464 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.463 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.463 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.463 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.463 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.463 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.463 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.462 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.462 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.462 | |
| 4kwh | NAP | Reductase homolog | / | 0.462 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.462 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.461 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.461 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.461 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.461 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.461 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.460 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.459 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.459 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.459 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.459 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.459 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.458 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.458 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.458 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.458 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.458 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.458 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.458 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.458 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.458 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.458 | |
| 4pd6 | URI | Nucleoside permease | / | 0.458 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.457 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.457 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.457 | |
| 1fml | RTL | Retinol dehydratase | / | 0.456 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.456 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.456 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.455 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.454 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.454 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.454 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.453 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.453 | |
| 2y3r | TRK | TamL | / | 0.453 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.453 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.453 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1sn5 | T3 | Transthyretin | / | 0.452 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.452 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.451 | |
| 1ppj | ANY | Cytochrome b | / | 0.451 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.451 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.451 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.450 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.450 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.449 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.449 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.449 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.448 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.448 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.448 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.448 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.448 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.448 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.448 | |
| 5j4e | FMN | Sensory box protein | / | 0.448 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 3h1j | SMA | Cytochrome b | / | 0.447 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.447 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1qvn | FRI | Interleukin-2 | / | 0.446 | |
| 1r2j | FAD | FkbI | / | 0.446 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.446 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.446 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.446 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.445 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.445 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.445 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.445 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.445 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 4k9u | 5AW | Cytochrome P450 3A4 | / | 0.445 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.445 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 4zas | TYD | CalS13 | / | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 1eio | GCH | Gastrotropin | / | 0.444 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.444 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.444 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.444 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.444 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.444 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3eej | 53R | Uncharacterized protein | / | 0.443 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.443 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.443 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.443 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.443 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.443 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.443 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.443 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.442 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.442 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.442 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.442 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.442 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.442 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.441 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3up3 | XCA | aceDAF-12 | / | 0.441 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.441 | |
| 4lb2 | DM5 | Serum albumin | / | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.441 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.441 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.440 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.440 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.440 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4cta | ATP | CinA-like protein | / | 0.440 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.440 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.440 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5env | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.440 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.440 |