Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 1.000 | |
2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.606 | |
2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.495 | |
2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 |