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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2agtFIDAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2agtFIDAldose reductase1.1.1.211.000
2pd9FIDAldose reductase1.1.1.210.767
2pdmZSTAldose reductase1.1.1.210.725
2pdwFIDAldose reductase1.1.1.210.721
1z8962PAldose reductase1.1.1.210.710
2pdkSBIAldose reductase1.1.1.210.691
1t40ID5Aldose reductase1.1.1.210.688
2iki388Aldose reductase1.1.1.210.663
2pdfZSTAldose reductase1.1.1.210.637
2f2kTGGAldose reductase1.1.1.210.634
4gca2X9Aldose reductase1.1.1.210.633
3p2vDOYAldose reductase1.1.1.210.632
2pdu393Aldose reductase1.1.1.210.630
4gabFIDAldo-keto reductase family 1 member B101.1.10.627
4yu153NAldose reductase1.1.1.210.626
3m4h388Aldose reductase1.1.1.210.625
5liu388Aldo-keto reductase family 1 member B101.1.10.623
1ekoI84Aldose reductase1.1.1.210.622
2iqdLPAAldose reductase1.1.1.210.622
2pdyFIDAldose reductase1.1.1.210.619
3lz5LDTAldose reductase1.1.1.210.619
2pdj393Aldose reductase1.1.1.210.618
2is72CLAldose reductase1.1.1.210.617
2pdh47DAldose reductase1.1.1.210.617
2ikj393Aldose reductase1.1.1.210.614
2pdg47DAldose reductase1.1.1.210.612
2inzOHPAldose reductase1.1.1.210.610
2nvcITAAldose reductase1.1.1.210.609
3lboLDTAldose reductase1.1.1.210.607
1adsNAPAldose reductase1.1.1.210.606
3u2cSUZAldose reductase1.1.1.210.606
2fz8ZSTAldose reductase1.1.1.210.600
3v35NTIAldose reductase1.1.1.210.600
3lqlLDTAldose reductase1.1.1.210.599
1x96NAPAldose reductase1.1.1.210.597
3mb9ZSTAldose reductase1.1.1.210.594
2hv5ZSTAldose reductase1.1.1.210.593
2pdxZSTAldose reductase1.1.1.210.593
1ef3FIDAldose reductase1.1.1.210.588
1ieiZESAldose reductase1.1.1.210.588
3s3gTLTAldose reductase1.1.1.210.588
2i17LDTAldose reductase1.1.1.210.587
2pzn393Aldose reductase1.1.1.210.586
4wevSUZAldo-keto reductase family 1 member B101.1.10.581
3ghtLDTAldose reductase1.1.1.210.580
2duxZSTAldose reductase1.1.1.210.578
3ghuLDTAldose reductase1.1.1.210.577
2dv0ZSTAldose reductase1.1.1.210.576
1ah0SBIAldose reductase1.1.1.210.575
1t41ID5Aldose reductase1.1.1.210.572
2pdiZSTAldose reductase1.1.1.210.571
2fz9ZSTAldose reductase1.1.1.210.570
3m64393Aldose reductase1.1.1.210.570
2pdq47DAldose reductase1.1.1.210.563
2fzdTOLAldose reductase1.1.1.210.562
1el3I84Aldose reductase1.1.1.210.559
2acuNAPAldose reductase1.1.1.210.557
2i16LDTAldose reductase1.1.1.210.556
3mc5393Aldose reductase1.1.1.210.555
2qxwLDTAldose reductase1.1.1.210.554
3v36NAPAldose reductase1.1.1.210.554
1pwmFIDAldose reductase1.1.1.210.553
3lenZSTAldose reductase1.1.1.210.553
2hvnZSTAldose reductase1.1.1.210.551
3ld5LDTAldose reductase1.1.1.210.545
2pdn47DAldose reductase1.1.1.210.543
2pdp393Aldose reductase1.1.1.210.543
1us0LDTAldose reductase1.1.1.210.541
3ghsLDTAldose reductase1.1.1.210.541
2pdc393Aldose reductase1.1.1.210.538
3m0iZSTAldose reductase1.1.1.210.536
3ghrLDTAldose reductase1.1.1.210.535
2ikhLITAldose reductase1.1.1.210.534
1z3n3NAAldose reductase1.1.1.210.532
4dbw511Aldo-keto reductase family 1 member C3/0.532
2hvoZSTAldose reductase1.1.1.210.528
4u95MIYMultidrug efflux pump subunit AcrB/0.528
2pdlTOLAldose reductase1.1.1.210.527
3g5eQ74Aldose reductase1.1.1.210.525
2pb1NFGGlucan 1,3-beta-glucosidase/0.522
1kmsLIHDihydrofolate reductase1.5.1.30.519
1u08PLPMethionine aminotransferase/0.517
2pd5ZSTAldose reductase1.1.1.210.517
1p0pBCHCholinesterase3.1.1.80.516
1z8aNAPAldose reductase1.1.1.210.516
3t423T4Aldose reductase1.1.1.210.516
2d06ESTSulfotransferase 1A12.8.2.10.515
3r8hZOMAldo-keto reductase family 1 member C3/0.515
2ipw2CLAldose reductase1.1.1.210.514
2bjsACVIsopenicillin N synthase1.21.3.10.513
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.513
1rxjBNIStreptavidin/0.512
2pf8NDPAldose reductase1.1.1.210.512
1pwlBFIAldose reductase1.1.1.210.511
1s36CEIObelin/0.511
2pevNDPAldose reductase1.1.1.210.511
2f3815MAldo-keto reductase family 1 member C3/0.510
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.509
2fzbTOLAldose reductase1.1.1.210.508
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.507
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.507
4ga8SBIAldo-keto reductase family 1 member B101.1.10.507
1e6zNGOChitinase/0.505
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.505
3r43ID8Aldo-keto reductase family 1 member C3/0.505
1qtiGNTAcetylcholinesterase3.1.1.70.504
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.20.504
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.504
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.504
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.503
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.500
2duzZSTAldose reductase1.1.1.210.500
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.500
5dsg0HKMuscarinic acetylcholine receptor M4/0.499
1dx6GNTAcetylcholinesterase3.1.1.70.498
2pdbZSTAldose reductase1.1.1.210.498
2w3mFOLDihydrofolate reductase1.5.1.30.498
4gg1TZDBenzoylformate decarboxylase4.1.1.70.498
1w35FADFerredoxin--NADP reductase1.18.1.20.497
2cekN8TAcetylcholinesterase3.1.1.70.496
2pucGUNHTH-type transcriptional repressor PurR/0.496
2xujTZ5Acetylcholinesterase3.1.1.70.496
3c1oNAPEugenol synthase/0.496
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.495
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.494
2xuhTZ4Acetylcholinesterase3.1.1.70.494
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.494
4jtrIZPAldo-keto reductase family 1 member C2/0.494
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.492
1ah3TOLAldose reductase1.1.1.210.491
1ry8RUTAldo-keto reductase family 1 member C3/0.491
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.491
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.491
1ah4NAPAldose reductase1.1.1.210.490
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.490
4n9qFMNFMN-dependent NADH-azoreductase 1/0.490
3gyf51PDihydrofolate reductase1.5.1.30.489
3l3rOAGDihydrofolate reductase1.5.1.30.489
4jhiEMUNodulin-13/0.489
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.489
1lkeDOGBilin-binding protein/0.488
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.488
1w6jR71Lanosterol synthase5.4.99.70.487
4qtnNNRNicotinamide riboside transporter PnuC/0.487
1zgbA1EAcetylcholinesterase3.1.1.70.486
2a2xNA9Prothrombin3.4.21.50.486
2bxqIMNSerum albumin/0.486
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.486
2z52H23Geranylgeranyl pyrophosphate synthase/0.486
1dlrMXADihydrofolate reductase1.5.1.30.485
1jf0CZHObelin/0.485
2cbqTH2Neocarzinostatin/0.485
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.485
4kn104JFolate receptor beta/0.485
1gpnHUBAcetylcholinesterase3.1.1.70.484
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.484
1t7o152Carnitine O-acetyltransferase2.3.1.70.483
1votHUPAcetylcholinesterase3.1.1.70.483
3r6iJMSAldo-keto reductase family 1 member C3/0.483
4u140HKMuscarinic acetylcholine receptor M3/0.483
1ihiIU5Aldo-keto reductase family 1 member C2/0.482
1zq5E04Aldo-keto reductase family 1 member C3/0.482
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.482
4kn2LYAFolate receptor beta/0.482
1frbZSTAldose reductase-related protein 2/0.481
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.481
3n0hTOPDihydrofolate reductase1.5.1.30.481
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.481
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.481
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
2a2sGSNGlutathione S-transferase P2.5.1.180.480
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.480
4mfpCOAUncharacterized protein/0.480
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.479
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.479
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.479
1el4CTZObelin/0.478
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.478
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.478
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.478
3stdMQ0Scytalone dehydratase4.2.1.940.478
4jq2SUZAldo-keto reductase family 1 member C2/0.478
2vcmM11Isopenicillin N synthase1.21.3.10.477
2z4y252Geranylgeranyl pyrophosphate synthase/0.477
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.477
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.477
4bvhAR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.477
4jqaID8Aldo-keto reductase family 1 member C2/0.477
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.476
1s07PLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.476
2w6cBM4Acetylcholinesterase3.1.1.70.476
3zv7NHGAcetylcholinesterase3.1.1.70.476
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.476
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4kebFOLDihydrofolate reductase1.5.1.30.476
2bd0NAPSepiapterin reductase/0.475
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.475
3o76GTBGlutathione S-transferase P 12.5.1.180.475
2yczI32Beta-1 adrenergic receptor/0.475
1d3dBZTProthrombin3.4.21.50.474
2aclL05Oxysterols receptor LXR-alpha/0.474
2ipjFFAAldo-keto reductase family 1 member C2/0.474
2rqfJH3Hemolymph juvenile hormone binding protein/0.474
3jq7DX2Pteridine reductase, putative/0.474
3n39FMNProtein NrdI/0.474
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
2xvw9NRSerum albumin/0.473
3af3GCPPantothenate kinase2.7.1.330.473
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.473
8catNDPCatalase1.11.1.60.473
5cxv0HKMuscarinic acetylcholine receptor M1/0.473
1sjwNGVNogalonic acid methyl ester cyclase/0.472
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.472
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.472
3bi6396Wee1-like protein kinase2.7.10.20.472
4blcNDPCatalase1.11.1.60.472
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.472
4m6l21VDihydrofolate reductase1.5.1.30.472
7catNDPCatalase1.11.1.60.472
1gw2FERPeroxidase C1A1.11.1.70.471
2cjeDUNDUTPase/0.471
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.471
2gyuHI6Acetylcholinesterase3.1.1.70.471
2oadGTBGlutathione S-transferase P 12.5.1.180.471
3gi2GHWDihydrofolate reductase1.5.1.30.471
3mytEQUSteroid Delta-isomerase5.3.3.10.471
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.471
3up3XCAaceDAF-12/0.471
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
5epvACPBlue-light-activated histidine kinase2.7.13.30.471
1xf0ASDAldo-keto reductase family 1 member C3/0.470
2nnqT4BFatty acid-binding protein, adipocyte/0.470
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.470
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.470
3nxtD2EDihydrofolate reductase1.5.1.30.470
5a4wQCTGlutathione S-transferase F22.5.1.180.470
1pq6965Oxysterols receptor LXR-beta/0.469
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.469
2xupTZ5Acetylcholinesterase3.1.1.70.469
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.469
3p70ILE_PHE_GLU_PRO_PROProthrombin3.4.21.50.469
1ry0PG2Aldo-keto reductase family 1 member C3/0.468
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.468
2qw8NAPEugenol synthase 11.1.1.3180.468
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.468
4i5xFLFAldo-keto reductase family 1 member B101.1.10.468
2ycxP32Beta-1 adrenergic receptor/0.468
1odnAPVIsopenicillin N synthase1.21.3.10.467
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.467
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.467
1c4yIH3Prothrombin3.4.21.50.466
1x2bSTXProline iminopeptidase3.4.11.50.466
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1zuaTOLAldo-keto reductase family 1 member B101.1.10.466
2bd0BIOSepiapterin reductase/0.466
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.466
2qryTPSThiamine-binding periplasmic protein/0.466
2vt4P32Beta-1 adrenergic receptor/0.466
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
3gwnFADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.466
3n3bFMNProtein NrdI/0.466
3ugrIMNAldo-keto reductase family 1 member C3/0.466
4b7zQ4QAcetylcholinesterase3.1.1.70.466
4dkbDUNDeoxyuridine triphosphatase, putative/0.466
4daj0HKMuscarinic acetylcholine receptor M3/0.466
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.465
1gt5BZQOdorant-binding protein/0.465
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.465
1zgcA2EAcetylcholinesterase3.1.1.70.465
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.465
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.465
4jtqFLPAldo-keto reductase family 1 member C2/0.465
1hfrMOTDihydrofolate reductase1.5.1.30.464
1lnmDTXBilin-binding protein/0.464
2xtbKRMAdenosine kinase, putative/0.464
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.464
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.464
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.464
4hmn16JAldo-keto reductase family 1 member C3/0.464
4jq4IMNAldo-keto reductase family 1 member C2/0.464
1dduDDUThymidylate synthase/0.463
2xi4AFTAcetylcholinesterase3.1.1.70.463
3c3dFO12-phospho-L-lactate transferase/0.463
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.463
3ghwGHWDihydrofolate reductase1.5.1.30.463
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
3zdnFADMonoamine oxidase N1.4.3.40.463
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.463
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.463
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.463
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.462
1jdzFMBPurine nucleoside phosphorylase/0.462
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.462
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.462
1w6rGNTAcetylcholinesterase3.1.1.70.462
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2dscAPRADP-sugar pyrophosphatase3.6.1.130.462
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.462
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.462
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
3gx9TXDMorphinone reductase/0.462
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.462
3r7mSUZAldo-keto reductase family 1 member C3/0.462
3v0n4GWHisto-blood group ABO system transferase/0.462
4n3l2FNProthrombin3.4.21.50.462
1jf2CZHObelin/0.461
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.461
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.461
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.461
1qv0CZHObelin/0.461
1s3uTQDDihydrofolate reductase1.5.1.30.461
1s9dAFBCytohesin-2/0.461
1s9dAFBADP-ribosylation factor 1/0.461
1yw8A75Methionine aminopeptidase 2/0.461
2zsbADPPantothenate kinase2.7.1.330.461
3af4GCPPantothenate kinase2.7.1.330.461
3f3y4OABile salt sulfotransferase2.8.2.140.461
3k47D09Dihydrofolate reductase1.5.1.30.461
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.461
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3zc3FADFerredoxin--NADP reductase1.18.1.20.461
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
4xo7ASDAldo-keto reductase family 1 member C2/0.461
1dduCB3Thymidylate synthase/0.460
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.460
1h35R01Squalene--hopene cyclase4.2.1.1290.460
1w7gMIUProthrombin3.4.21.50.460
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.460
1ypjUIBProthrombin3.4.21.50.460
2xuqTZ4Acetylcholinesterase3.1.1.70.460
3e6eDCSAlanine racemase/0.460
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.460
3i9kNADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.460
3t0kDCQSulfide-quinone reductase/0.460
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.460
3vo2FADFerredoxin--NADP reductase/0.460
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.460
4c9wVGH7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.460
5fljQUEQuercetinase QueD/0.460
1dgfNDPCatalase1.11.1.60.459
1esmCOAPantothenate kinase2.7.1.330.459
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.459
1mvtDTMDihydrofolate reductase1.5.1.30.459
1qjgEQUSteroid Delta-isomerase5.3.3.10.459
2b8jADNClass B acid phosphatase3.1.3.20.459
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.459
2f59INI6,7-dimethyl-8-ribityllumazine synthase 1/0.459
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.459
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.459
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.459
2v7tSAH5'-fluoro-5'-deoxy-adenosine synthase/0.459
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
4bjbP34Tankyrase-22.4.2.300.459
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
4kfjFOLDihydrofolate reductase1.5.1.30.459
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
1ohkCOPDihydrofolate reductase1.5.1.30.458
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.458
1pj6FOLDimethylglycine oxidase1.5.3.100.458
1vkgCRIHistone deacetylase 83.5.1.980.458
1x8lOXRRetinol dehydratase/0.458
2geuCOKPantothenate kinase2.7.1.330.458
2qimZEAClass 10 plant pathogenesis-related protein/0.458
2zevIPEGeranylgeranyl pyrophosphate synthase/0.458
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.458
3b9lAZZSerum albumin/0.458
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3d2dRENReticuline oxidase1.21.3.30.458
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.458
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.458
4bfuZVUPantothenate kinase2.7.1.330.458
4dbs0HVAldo-keto reductase family 1 member C3/0.458
4je5PLPAromatic/aminoadipate aminotransferase 12.6.1.390.458
4kn0MTXFolate receptor beta/0.458
4lrrCF9Thymidylate synthase/0.458
1acjTHAAcetylcholinesterase3.1.1.70.457
1dr4HBIDihydrofolate reductase1.5.1.30.457
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.457
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.457
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.457
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.457
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2hzqSTRApolipoprotein D/0.457
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.457
2qx7NAPEugenol synthase 11.1.1.3180.457
3aezGDPPantothenate kinase2.7.1.330.457
3bm4ADVADP-sugar pyrophosphatase3.6.1.130.457
3eq02TSProthrombin3.4.21.50.457
3zkuHCVIsopenicillin N synthase1.21.3.10.457
4jq3ZOMAldo-keto reductase family 1 member C2/0.457
4li61XOTankyrase-12.4.2.300.457
4stdBFSScytalone dehydratase4.2.1.940.457
1eveE20Acetylcholinesterase3.1.1.70.456
1o5gCR9Prothrombin3.4.21.50.456
1ohjCOPDihydrofolate reductase1.5.1.30.456
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
1sm4FADFerredoxin--NADP reductase/0.456
2gbyBRNHTH-type transcriptional regulator QacR/0.456
2vrjNCWBeta-glucosidase A3.2.1.210.456
2xltNA0Putative flavin-containing monooxygenase/0.456
3mjrAC2Deoxycytidine kinase2.7.1.740.456
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.456
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.456
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.456
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.456
1lelBH7Avidin/0.455
1n5vNOMActVA 6 protein/0.455
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.455
1yw9A84Methionine aminopeptidase 2/0.455
2aj4ANPGalactokinase2.7.1.60.455
2b07598Tyrosine-protein phosphatase non-receptor type 13.1.3.480.455
2gesCOKPantothenate kinase2.7.1.330.455
2uuk897Prothrombin3.4.21.50.455
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2xuoTZ4Acetylcholinesterase3.1.1.70.455
3cth319Hepatocyte growth factor receptor2.7.10.10.455
3dhk23UProthrombin3.4.21.50.455
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.455
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.455
3ug8IMNAldo-keto reductase family 1 member C3/0.455
4cb593GPolymerase basic protein 2/0.455
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4rn615UProthrombin3.4.21.50.455
4xczT3QQdtf/0.455
1az1ALRAldose reductase1.1.1.210.454
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1pkfEPDEpothilone C/D epoxidase1.140.454
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.454
2cf9348Prothrombin3.4.21.50.454
2jl1NAPTriphenylmethane reductase/0.454
2w3bNDPDihydrofolate reductase1.5.1.30.454
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3fsjD7KBenzoylformate decarboxylase4.1.1.70.454
3p2hMTAAcyl-homoserine-lactone synthase/0.454
3qftFADNADPH--cytochrome P450 reductase/0.454
3r8gIZPAldo-keto reductase family 1 member C3/0.454
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4a7zAY9Aldos-2-ulose dehydratase/0.454
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.454
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.454
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
1gj5130Prothrombin3.4.21.50.453
1gky5GPGuanylate kinase2.7.4.80.453
1o6qR17Squalene--hopene cyclase4.2.1.1290.453
1r58AO5Methionine aminopeptidase 2/0.453
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.453
1swgBTNStreptavidin/0.453
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.453
1umaIN2Prothrombin3.4.21.50.453
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.453
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.453
2gmvUN8Phosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.453
2hdjNDPAldo-keto reductase family 1 member C2/0.453
2zseACPPantothenate kinase2.7.1.330.453
3cfoGMPDNA-directed DNA polymerase/0.453
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.453
3iu7FCDMethionine aminopeptidase 2/0.453
3o3rNAPAldose reductase-related protein 11.1.1.210.453
3r9fGSUMccE protein/0.453
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.453
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.453
4bjcRPBTankyrase-22.4.2.300.453
4e7r0NWProthrombin3.4.21.50.453
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.453
4j7gTRHPCZA361.3/0.453
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.453
1gjrFADFerredoxin--NADP reductase1.18.1.20.452
1q83TZ5Acetylcholinesterase3.1.1.70.452
1zrqNAI5,10-methylenetetrahydrofolate reductase1.5.1.200.452
2b82ADNClass B acid phosphatase3.1.3.20.452
2ckmAA7Acetylcholinesterase3.1.1.70.452
2zhe13UProthrombin3.4.21.50.452
3b9gIMHIAG-nucleoside hydrolase/0.452
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
4cb629RPolymerase basic protein 2/0.452
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.452
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.452
4m6kFOLDihydrofolate reductase1.5.1.30.452
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.452
1obnASVIsopenicillin N synthase1.21.3.10.451
1x2eATXProline iminopeptidase3.4.11.50.451
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.451
2aot2PMHistamine N-methyltransferase2.1.1.80.451
2j3qTFLAcetylcholinesterase3.1.1.70.451
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.451
2xufTZ4Acetylcholinesterase3.1.1.70.451
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3fu83DMLaccase-11.10.3.20.451
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3gusN11Glutathione S-transferase P2.5.1.180.451
3hl0NADMaleylacetate reductase/0.451
3jqgAX6Pteridine reductase, putative/0.451
3lakKR1Gag-Pol polyprotein2.7.7.490.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3nxvD2FDihydrofolate reductase1.5.1.30.451
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4fal0T0Aldo-keto reductase family 1 member C3/0.451
4relKMPGlycosyltransferase/0.451
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.451
5stdUNNScytalone dehydratase4.2.1.940.451
1c4uIH1Prothrombin3.4.21.50.450
1hb3SCVIsopenicillin N synthase1.21.3.10.450
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1odcA8BAcetylcholinesterase3.1.1.70.450
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.450
1qgzFADFerredoxin--NADP reductase1.18.1.20.450
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.450
1touB1VFatty acid-binding protein, adipocyte/0.450
1w4lGL8Acetylcholinesterase3.1.1.70.450
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2a5c8DAAvidin/0.450
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.450
2iuzD1HEndochitinase B13.2.1.140.450
2pfhNDPAldose reductase1.1.1.210.450
2wzySQXSoluble acetylcholine receptor/0.450
2zgx29UProthrombin3.4.21.50.450
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.450
3ewkFADSensory box histidine kinase/response regulator/0.450
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.450
3lg5BTMEpi-isozizaene synthase4.2.3.370.450
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.450
3nxoD2BDihydrofolate reductase1.5.1.30.450
4l1xSTRAldo-keto reductase family 1 member C2/0.450
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.450
4qa2SHHHistone deacetylase 83.5.1.980.450
4zqcF6FTryptophan synthase alpha chain/0.450
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.449
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2fzjDH3Dihydrofolate reductase1.5.1.30.449
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2vq7NAPPutative flavin-containing monooxygenase/0.449
3c0zSHHHistone deacetylase 73.5.1.980.449
3htjETEbrA repressor/0.449
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3nu03TUDihydrofolate reductase1.5.1.30.449
3t31DCQSulfide-quinone reductase/0.449
3uweVJJAldo-keto reductase family 1 member C3/0.449
3w0uHPWLactoylglutathione lyase4.4.1.50.449
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.449
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.449
4c73TLH3-oxoacyl-ACP synthase/0.449
4cbyKEEHistone deacetylase 43.5.1.980.449
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.449
4j7hTRHPCZA361.3/0.449
4jjkFOLFormate--tetrahydrofolate ligase/0.449
4khnXG4DNA-directed DNA polymerase/0.449
4n1fCZHObelin/0.449
4psbGA3Cytokinin-specific binding protein/0.449
1dghNDPCatalase1.11.1.60.448
1fmjRTLRetinol dehydratase/0.448
1kmvLIIDihydrofolate reductase1.5.1.30.448
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1qv1CZHObelin/0.448
1x1aSAMC-20 methyltransferase/0.448
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.448
2ohhFMNType A flavoprotein FprA10.448
2tplHPPTyrosine phenol-lyase4.1.99.20.448
2xnvVU3Soluble acetylcholine receptor/0.448
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2zc922UProthrombin3.4.21.50.448
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3r94FLRAldo-keto reductase family 1 member C3/0.448
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.448
4b1e6T6Beta-secretase 13.4.23.460.448
4dz5NAPAldo-keto reductase family 1 member C3/0.448
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.448
4qa0SHHHistone deacetylase 83.5.1.980.448
1aqv0HGGlutathione S-transferase P2.5.1.180.447
1dhfFOLDihydrofolate reductase1.5.1.30.447
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.447
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.447
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.447
2ea4F79Methionine aminopeptidase 2/0.447
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.447
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.447
2xuiTZ5Acetylcholinesterase3.1.1.70.447
2zevB71Geranylgeranyl pyrophosphate synthase/0.447
2zsaADPPantothenate kinase2.7.1.330.447
3aosJH2Hemolymph juvenile hormone binding protein/0.447
3dz6M8ES-adenosylmethionine decarboxylase proenzyme4.1.1.500.447
3fvuIACKynurenine--oxoglutarate transaminase 12.6.1.70.447
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.447
3gncQQQGlutaryl-CoA dehydrogenase/0.447
3ocw3AMLipoprotein E/0.447
3q9bB3NAcetylpolyamine amidohydrolase/0.447
3qeoLLTDeoxycytidine kinase2.7.1.740.447
3w5uFADFerredoxin/0.447
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.447
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.447
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.447
4fa30SLAldo-keto reductase family 1 member C3/0.447
4hfp15UProthrombin3.4.21.50.447
4nhkPD2Prolyl 3,4-dihydroxylase TPA11.14.110.447
4pnmNU1Tankyrase-22.4.2.300.447
4zasTYDCalS13/0.447
7stdCRPScytalone dehydratase4.2.1.940.447
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1u65CP0Acetylcholinesterase3.1.1.70.446
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2ha6SCKAcetylcholinesterase3.1.1.70.446
2vqbNAPPutative flavin-containing monooxygenase/0.446
2vqqTFGHistone deacetylase 43.5.1.980.446
2yw9NAPEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
2zsdCOAPantothenate kinase2.7.1.330.446
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3gf4U5PUDP-galactopyranose mutase5.4.99.90.446
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.446
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.446
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.446
4d6qPD2Lysine-specific demethylase 4D1.14.110.446
4xoqF42Coenzyme F420:L-glutamate ligase/0.446
5cmx0G6Prothrombin3.4.21.50.446
5jdzSAHMethyl transferase/0.446
4u163C0Muscarinic acetylcholine receptor M3/0.446
1g3mPCQEstrogen sulfotransferase2.8.2.40.445
1gj4132Prothrombin3.4.21.50.445
1towCRZFatty acid-binding protein, adipocyte/0.445
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2a8gGNGAvidin/0.445
2hctNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.445
2qdsMCOMetallo-beta-lactamase type 2/0.445
3ab1FADFerredoxin--NADP reductase1.18.1.20.445
3c1kT15Prothrombin3.4.21.50.445
3iu9T07Methionine aminopeptidase 2/0.445
3n3aFMNProtein NrdI/0.445
3udj092Beta-secretase 13.4.23.460.445
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4ey6GNTAcetylcholinesterase3.1.1.70.445
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.445
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.444
1blzACVIsopenicillin N synthase1.21.3.10.444
1g60SAMModification methylase MboII2.1.1.720.444
1jwtBLIProthrombin3.4.21.50.444
1pj7FFODimethylglycine oxidase1.5.3.100.444
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
1rszDIHPurine nucleoside phosphorylase2.4.2.10.444
1vf2GTXGlutathione S-transferase 32.5.1.180.444
2gvvDI9Diisopropyl-fluorophosphatase3.1.8.20.444
2j7dGI1Beta-glucosidase A3.2.1.210.444
2oacGTBGlutathione S-transferase P 12.5.1.180.444
2qg2A91Heat shock protein HSP 90-alpha/0.444
2xugTZ4Acetylcholinesterase3.1.1.70.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3fr5I4AFatty acid-binding protein, adipocyte/0.444
3nxyD2HDihydrofolate reductase1.5.1.30.444
3szfDCQSulfide-quinone reductase/0.444
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.444
4b66NAPL-ornithine N(5)-monooxygenase/0.444
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.444
4fam0SZAldo-keto reductase family 1 member C3/0.444
4p9dTMPDeoxycytidylate deaminase/0.444
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.444
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.444
1bk0ACVIsopenicillin N synthase1.21.3.10.443
1d3pBT3Prothrombin3.4.21.50.443
1dpmEBPParathion hydrolase3.1.8.10.443
1ej3CZHAequorin-2/0.443
2ch2KY1Serine--pyruvate aminotransferase/0.443
2ct8MSPMethionine--tRNA ligase6.1.1.100.443
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.443
2ejzSAHDiphthine synthase/0.443
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.443
2gg0U11Methionine aminopeptidase/0.443
2gywOBIAcetylcholinesterase3.1.1.70.443
2h7jH7JCathepsin S3.4.22.270.443
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.443
2q92B23Methionine aminopeptidase/0.443
2r6jNDPEugenol synthase 11.1.1.3180.443
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
2zhf49UProthrombin3.4.21.50.443
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
3cv6HXSAldo-keto reductase family 1 member C21/0.443
3h4vDVPPteridine reductase 11.5.1.330.443
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.443
3irhDTPHD domain protein/0.443
3lzzGDPUncharacterized protein/0.443
3nwlNDPCatalase1.11.1.60.443
3p9tTCLRepressor/0.443
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.443
3vjcZGASqualene synthase2.5.1.210.443
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.443
4a7yNHFAldos-2-ulose dehydratase/0.443
4bprFADFerredoxin--NADP reductase1.18.1.20.443
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443
4phlPILPhosphodiesterase/0.443
1d6w00RProthrombin3.4.21.50.442
1dgbNDPCatalase1.11.1.60.442
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.442
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.442
1upw444Oxysterols receptor LXR-beta/0.442
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2za0MGILactoylglutathione lyase4.4.1.50.442
3a1l2CCCytochrome P450/0.442
3af1GDPPantothenate kinase2.7.1.330.442
3h0wN8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.442
3ko3ADPD-tyrosyl-tRNA(Tyr) deacylase/0.442
3njoPYVAbscisic acid receptor PYR1/0.442
3rthRTHBeta-secretase 13.4.23.460.442
3t37FADPyridoxine 4-oxidase/0.442
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4ax9N5NProthrombin3.4.21.50.442
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.442
4l0oPLPCystathionine gamma-synthase2.5.1.480.442
4m0f1YKAcetylcholinesterase3.1.1.70.442
5gcnCOAHAT A1/0.442
9mhtSAHModification methylase HhaI2.1.1.370.442
1e1cDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.441
1e66HUXAcetylcholinesterase3.1.1.70.441
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1h42FADFerredoxin--NADP reductase1.18.1.20.441
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.441
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.441
1u70MTXDihydrofolate reductase1.5.1.30.441
1yw7A41Methionine aminopeptidase 2/0.441
2cn0F25Prothrombin3.4.21.50.441
2gl0ADNUncharacterized protein/0.441
2gqnBLPCystathionine beta-lyase MetC4.4.1.80.441
2ij7TPFMycocyclosin synthase1.14.21.90.441
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.441
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.441
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.441
2po7CHDFerrochelatase, mitochondrial4.99.1.10.441
2vutNADNitrogen metabolite repression protein nmrA/0.441
2y60M8FIsopenicillin N synthase1.21.3.10.441
3af2ACPPantothenate kinase2.7.1.330.441
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.441
3bi2FADPolyamine oxidase FMS1/0.441
3bldPRFQueuine tRNA-ribosyltransferase2.4.2.290.441
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.441
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.441
3jq6DX1Pteridine reductase, putative/0.441
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.441
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4azwSAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.441
4juiEGRTannase/0.441
4jvmXDIEstrogen sulfotransferase2.8.2.40.441
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.441
1b2lNDCAlcohol dehydrogenase1.1.1.10.440
1clqGDPDNA-directed DNA polymerase/0.440
1e2jTHMThymidine kinase/0.440
1e2lTMCThymidine kinase/0.440
1gawFADFerredoxin/0.440
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1s7gNADNAD-dependent protein deacylase 2/0.440
1vfsDCSAlanine racemase/0.440
1yqdNAPSinapyl alcohol dehydrogenase/0.440
2bu5TF1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.440
2fycGDUBeta-1,4-galactosyltransferase 12.4.10.440
2getCOKPantothenate kinase2.7.1.330.440
2gvcFADThiol-specific monooxygenase1.14.130.440
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.440
2wjoQUDBeta-secretase 13.4.23.460.440
2zf051UProthrombin3.4.21.50.440
2zfq45UProthrombin3.4.21.50.440
2zi224UProthrombin3.4.21.50.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.440
3cuiX4SExoglucanase/xylanase3.2.1.910.440
3d27W29Methionine aminopeptidase/0.440
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.440
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440
4dyp0MSNucleoprotein/0.440
4jlm1NNDeoxycytidine kinase2.7.1.740.440
4jtpASCRibosome inactivating protein/0.440
4kxjP34Nucleoprotein/0.440
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.440
4mrxCZHObelin/0.440
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
4uugPXGBranched-chain amino acid aminotransferase, putative/0.440
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.440
5je4SAHMethyl transferase/0.440