sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2af3 | COA | Phosphate acetyltransferase | 2.3.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2af3 | COA | Phosphate acetyltransferase | 2.3.1.8 | 1.000 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.472 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 3u9e | COA | Lmo1369 protein | / | 0.458 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.452 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.452 | |
| 2owg | SAH | Diphthine synthase | / | 0.449 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.445 | |
| 2e4n | SAH | Diphthine synthase | / | 0.444 | |
| 2e7r | SAH | Diphthine synthase | / | 0.443 | |
| 2ejk | SAH | Diphthine synthase | / | 0.443 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.441 | |
| 2huv | SAH | Diphthine synthase | / | 0.440 |