sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2ada	HPR	Adenosine deaminase	3.5.4.4

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2ada	HPR	Adenosine deaminase	3.5.4.4	1.000
1fkx	PRH	Adenosine deaminase	3.5.4.4	0.720
1fkw	PUR	Adenosine deaminase	3.5.4.4	0.698
1a4l	DCF	Adenosine deaminase	3.5.4.4	0.607
1wxy	FRK	Adenosine deaminase	3.5.4.4	0.538
1uml	FR4	Adenosine deaminase	3.5.4.4	0.522
1v7a	FRC	Adenosine deaminase	3.5.4.4	0.519
1ndy	FR3	Adenosine deaminase	3.5.4.4	0.515
1qxl	FR8	Adenosine deaminase	3.5.4.4	0.513
1ndz	FR5	Adenosine deaminase	3.5.4.4	0.498
1o5r	FR9	Adenosine deaminase	3.5.4.4	0.490
1uio	HPR	Adenosine deaminase	3.5.4.4	0.490