sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2a9y	26A	Adenosine kinase	2.7.1.20

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2a9y	26A	Adenosine kinase	2.7.1.20	1.000
2ab8	MTP	Adenosine kinase	2.7.1.20	0.749
2a9z	26A	Adenosine kinase	2.7.1.20	0.586
2gjl	FMN	Nitronate monooxygenase	1.13.12.16	0.487
2gjn	FMN	Nitronate monooxygenase	1.13.12.16	0.455
3in6	FMN	Uncharacterized protein	/	0.446
2zvc	SAH	Precorrin-3 C17-methyltransferase	/	0.444
3t4e	NAD	Quinate/shikimate dehydrogenase	/	0.444
4kla	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.443
2iku	LIY	Renin	3.4.23.15	0.440
4f4d	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.440