sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 1.000 | |
| 2gh6 | CF3 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.566 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.503 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.445 |