Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1zw5 | ZOL | Farnesyl pyrophosphate synthase | 2.5.1.10 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1zw5 | ZOL | Farnesyl pyrophosphate synthase | 2.5.1.10 | 1.000 | |
4nke | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.588 | |
3ldw | ZOL | Farnesyl pyrophosphate synthase, putative | / | 0.577 | |
4q23 | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.567 | |
3ez3 | ZOL | Farnesyl pyrophosphate synthase, putative | / | 0.564 | |
4kqs | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.564 | |
4lfv | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.561 | |
2opm | NI9 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.547 | |
3krf | DST | Geranyl diphosphate synthase large subunit | / | 0.524 | |
1rqj | RIS | Farnesyl diphosphate synthase | 2.5.1.10 | 0.514 | |
3ryw | K9H | Farnesyl pyrophosphate synthase, putative | / | 0.509 | |
4nke | IPE | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.505 | |
3ldw | IPE | Farnesyl pyrophosphate synthase, putative | / | 0.504 | |
2opn | SUF | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.501 | |
3ez3 | IPE | Farnesyl pyrophosphate synthase, putative | / | 0.500 | |
3krf | IPE | Geranyl diphosphate synthase large subunit | / | 0.486 | |
4kqs | IPE | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.486 | |
3oab | DST | Geranyl diphosphate synthase large subunit | / | 0.482 | |
4lfg | IPE | Putative geranyltranstransferase | / | 0.481 | |
3dyh | 721 | Farnesyl pyrophosphate synthase | / | 0.471 | |
3egt | 722 | Farnesyl pyrophosphate synthase | / | 0.464 | |
1rqj | IPE | Farnesyl diphosphate synthase | 2.5.1.10 | 0.463 | |
2f94 | BFQ | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.461 | |
4dwb | 0M7 | Farnesyl pyrophosphate synthase | / | 0.449 |