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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zmdFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1zmdFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.41.000
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.605
2eq7FADDihydrolipoyl dehydrogenase/0.577
1lvlFADDihydrolipoyl dehydrogenase1.8.1.40.544
3ladFADDihydrolipoyl dehydrogenase/0.543
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.541
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.526
1geuFADGlutathione reductase1.8.1.70.525
1zk7FADMercuric reductase1.16.1.10.514
3urhFADDihydrolipoyl dehydrogenase/0.507
2eq8FADDihydrolipoyl dehydrogenase/0.505
1onfFADGlutathione reductase1.8.1.70.501
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.496
2rabFADGlutathione amide reductase/0.495
2r9zFADGlutathione amide reductase/0.494
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.492
1grbFADGlutathione reductase, mitochondrial1.8.1.70.482
2zzcFADThioredoxin reductase 1, cytoplasmic1.8.1.90.481
1gerFADGlutathione reductase1.8.1.70.465
1nhqFADNADH peroxidase1.11.1.10.455
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.90.454
1getFADGlutathione reductase1.8.1.70.453
3djgFADGlutathione reductase, mitochondrial1.8.1.70.453