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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zj70ZTGag-Pol polyprotein3.4.23.16

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1zj70ZTGag-Pol polyprotein3.4.23.161.000
3tlh3TLGag-Pol polyprotein3.4.23.160.673
3psuLJGGag-Pol polyprotein3.4.23.160.638
2az93TLGag-Pol polyprotein3.4.23.160.621
1zpaA83Gag-Pol polyprotein3.4.23.160.612
1ytiPHE_LEU_GLU_LYSGag-Pol polyprotein/0.603
1zp8AB2Protease/0.603
2az83TLGag-Pol polyprotein3.4.23.160.589
4fe60TQGag-Pol polyprotein3.4.23.160.587
2hah3TLPOL protein/0.585
3kfp3TLGag-Pol polyprotein/0.565
2azb3TLGag-Pol polyprotein3.4.23.160.558
1fb7ROCGag-Pol polyprotein/0.555
1upjU01Gag-Pol polyprotein/0.554
1b113TLPol polyprotein/0.522
1hegPSIGag-Pol polyprotein/0.522
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.511
2fmbLP1Reverse transcriptase/0.509
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.506
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.506
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.506
4nmbFADBifunctional protein PutA/0.506
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.504
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.500
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.500
4aa4QC0Mitogen-activated protein kinase 14/0.499
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.499
4eh70OOMitogen-activated protein kinase 14/0.499
1fmbHYBPol polyprotein/0.498
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.498
2xru400Aurora kinase A2.7.11.10.498
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.498
2itnANPEpidermal growth factor receptor2.7.10.10.497
3r0yRSZPol protein/0.497
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.496
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.494
3dt1P40Mitogen-activated protein kinase 14/0.493
3flzFLZMitogen-activated protein kinase 14/0.493
2oji33AMitogen-activated protein kinase 12.7.11.240.492
3bheBZNGag-Pol polyprotein3.4.23.160.492
3iphG11Mitogen-activated protein kinase 14/0.490
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.489
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.488
3hx4ANPCalmodulin-domain protein kinase 1/0.488
3uyt0CKCasein kinase I isoform delta2.7.11.10.488
4kb81QOCasein kinase I isoform delta2.7.11.10.488
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.487
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.487
4uyf73BBromodomain-containing protein 2/0.487
3ukuC69Actin-related protein 3/0.484
3zh8C58Protein kinase C iota type2.7.11.130.484
4l4aCAMCamphor 5-monooxygenase1.14.15.10.484
1dz6CAMCamphor 5-monooxygenase1.14.15.10.483
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.483
4aacAAVMitogen-activated protein kinase 14/0.482
4cp4CAMCamphor 5-monooxygenase1.14.15.10.482
4s34ANPMitogen-activated protein kinase 12.7.11.240.482
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.481
2xjjL81Heat shock protein HSP 90-alpha/0.481
3fklFKLMitogen-activated protein kinase 14/0.481
3hl7I47Mitogen-activated protein kinase 14/0.481
3le62BZCyclin-dependent kinase 22.7.11.220.481
4jqeANPCasein kinase II subunit alpha2.7.11.10.481
1xddAAYIntegrin alpha-L/0.480
4gk2L66Ephrin type-A receptor 32.7.10.10.480
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.480
1jhqPMONicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.479
2a1mCAMCamphor 5-monooxygenase1.14.15.10.479
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.479
1svlADPLarge T antigen3.6.40.478
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.476
2cppCAMCamphor 5-monooxygenase1.14.15.10.476
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.476
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.476
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.476
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.476
3cppCAMCamphor 5-monooxygenase1.14.15.10.476
3wb2YGPUncharacterized protein MJ0488/0.476
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.475
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
1xl2189Gag-Pol polyprotein3.4.23.160.474
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.474
4dpy2P0Mevalonate diphosphate decarboxylase/0.474
4mv8ACPBiotin carboxylase6.3.4.140.474
1hiiC20Gag-Pol polyprotein/0.473
1n3rGTPGTP cyclohydrolase 13.5.4.160.473
1zky689Estrogen receptor/0.473
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.473
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.473
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.473
1kfbIGPTryptophan synthase alpha chain/0.472
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.472
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.472
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.472
3bc4LLGGag-Pol polyprotein3.4.23.160.472
3vjoANPEpidermal growth factor receptor2.7.10.10.472
1iwjCAMCamphor 5-monooxygenase1.14.15.10.471
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.471
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.471
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.471
2vgoAD5Aurora kinase B-A2.7.11.10.471
3upf0BUPolyprotein/0.471
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.471
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.471
4zp1TPPPyruvate decarboxylase4.1.1.10.471
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.471
5dr2ATPAurora kinase A2.7.11.10.471
1dr3HBIDihydrofolate reductase1.5.1.30.470
1phePIYCamphor 5-monooxygenase1.14.15.10.470
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.470
2acxANPG protein-coupled receptor kinase 62.7.11.160.470
2qo9ANPEphrin type-A receptor 32.7.10.10.470
3a62STURibosomal protein S6 kinase beta-12.7.11.10.470
3hekBD0Heat shock protein HSP 90-alpha/0.470
4fivLP1POL protein/0.470
4l4fCAMCamphor 5-monooxygenase1.14.15.10.470
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.470
3uleC69Actin-related protein 3/0.469
4o2bLOCTubulin beta-2B chain/0.469
1ezvUQ6Cytochrome b/0.468
1ia3TQ5Dihydrofolate reductase1.5.1.30.468
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.468
1l5oNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.468
1m17AQ4Epidermal growth factor receptor2.7.10.10.468
2xd6XD6ATP-dependent molecular chaperone HSP82/0.468
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.468
4hgs15GCasein kinase I isoform gamma-32.7.11.10.468
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.467
1uyuCAMCamphor 5-monooxygenase1.14.15.10.467
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.467
2csnCKICasein kinase I homolog 12.7.11.10.467
2zawCAMCamphor 5-monooxygenase1.14.15.10.467
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.467
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
3s4qNK0Mitogen-activated protein kinase 14/0.467
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.467
4deg0JJHepatocyte growth factor receptor2.7.10.10.467
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.467
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.467
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.466
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.466
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
3flyFLYMitogen-activated protein kinase 14/0.466
3ujlA8SAbscisic acid receptor PYL2/0.466
4ehzJAKTyrosine-protein kinase JAK1/0.466
4qmzB49Serine/threonine-protein kinase 242.7.11.10.466
4qnaX11Serine/threonine-protein kinase 242.7.11.10.466
1t87CAMCamphor 5-monooxygenase1.14.15.10.465
2briANPUridylate kinase2.7.4.220.465
2fznFADBifunctional protein PutA1.5.5.20.465
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.465
3o9aK14Pol polyprotein/0.465
3o9iA61Gag-Pol polyprotein/0.465
3qyw6PBMitogen-activated protein kinase 12.7.11.240.465
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.465
4g3rCAMCamphor 5-monooxygenase1.14.15.10.465
5cp4CAMCamphor 5-monooxygenase1.14.15.10.465
1dljUGAUDP-glucose 6-dehydrogenase/0.464
1l4eRBZNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.464
1l4kNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.464
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.464
2balPQAMitogen-activated protein kinase 14/0.464
2jkkBI9Focal adhesion kinase 12.7.10.20.464
2qi0MZ3Gag-Pol polyprotein/0.464
2rlcCHDCholoylglycine hydrolase3.5.1.240.464
3a292T0Fructose-1,6-bisphosphatase 13.1.3.110.464
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.464
3s2pPMUCyclin-dependent kinase 22.7.11.220.464
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.464
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.464
4e4m0NHTyrosine-protein kinase JAK2/0.464
4ipeANPTNF receptor-associated protein 1/0.464
4kin1M8Mitogen-activated protein kinase 14/0.464
5d4vSAHUncharacterized protein MJ0489/0.464
1f123HCHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
1h74ADPHomoserine kinase2.7.1.390.463
1kvkATPMevalonate kinase2.7.1.360.463
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.463
2dwbANPAurora kinase A2.7.11.10.463
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.463
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.463
2itxANPEpidermal growth factor receptor2.7.10.10.463
2yi7BZ8Heat shock protein HSP 90-alpha/0.463
3a8wATPProtein kinase C iota type2.7.11.130.463
3rvg17PTyrosine-protein kinase JAK2/0.463
3sheI85MAP kinase-activated protein kinase 32.7.11.10.463
4eh60ONMitogen-activated protein kinase 14/0.463
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.463
4fod0UVALK tyrosine kinase receptor2.7.10.10.463
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1kfcIPLTryptophan synthase alpha chain/0.462
2bpoNAPNADPH--cytochrome P450 reductase/0.462
2cchATPCyclin-dependent kinase 22.7.11.220.462
2itpAEEEpidermal growth factor receptor2.7.10.10.462
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.462
2y6o1N1Ephrin type-A receptor 42.7.10.10.462
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.462
2z54AB1Gag-Pol polyprotein3.4.23.160.462
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.462
3oibFDAPutative acyl-CoA dehydrogenase/0.462
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.462
4aa5NQBMitogen-activated protein kinase 14/0.462
4c9pCAMCytochrome P450/0.462
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.462
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.462
4j54G52Gag-Pol polyprotein3.4.23.160.462
4njsG08Protease/0.462
1oecAA2Fibroblast growth factor receptor 2/0.461
2eb3ANPEpidermal growth factor receptor2.7.10.10.461
2ghlLIBMitogen-activated protein kinase 14/0.461
2itqITQEpidermal growth factor receptor2.7.10.10.461
3bv2P38Mitogen-activated protein kinase 14/0.461
3fwfCAMCamphor 5-monooxygenase1.14.15.10.461
3gi3B10Mitogen-activated protein kinase 14/0.461
3mvm39PMitogen-activated protein kinase 14/0.461
3sa8K83Protease/0.461
4an4DUDPutative glycosyl transferase/0.461
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4fuxE75Mitogen-activated protein kinase 12.7.11.240.461
4l4bCAMCamphor 5-monooxygenase1.14.15.10.461
5auvAGIDeath-associated protein kinase 12.7.11.10.461
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.461
1me8RVPInosine-5'-monophosphate dehydrogenase/0.460
1ppl1Z7Penicillopepsin-13.4.23.200.460
2bf4NAPNADPH--cytochrome P450 reductase/0.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2itwITQEpidermal growth factor receptor2.7.10.10.460
2izuP01Casein kinase I isoform gamma-32.7.11.10.460
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.460
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3nww3NWMitogen-activated protein kinase 14/0.460
3oxw017Gag-Pol polyprotein3.4.23.160.460
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.460
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.460
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.460
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.460
4jx1CAHCamphor 5-monooxygenase1.14.15.10.460
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.460
5dr9SKEAurora kinase A2.7.11.10.460
1csnATPCasein kinase I homolog 12.7.11.10.459
1sxjADPReplication factor C subunit 5/0.459
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.459
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.459
2qd9LGFMitogen-activated protein kinase 14/0.459
2qhyMZ1Gag-Pol polyprotein/0.459
2qi4MZ6Gag-Pol polyprotein/0.459
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.459
2y9qANPMitogen-activated protein kinase 12.7.11.240.459
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.459
2z7lS91Mitogen-activated protein kinase 12.7.11.240.459
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.459
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.459
3fln3FNMitogen-activated protein kinase 14/0.459
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.459
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.459
4i231C9Epidermal growth factor receptor2.7.10.10.459
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.459
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.458
1rx1NAPDihydrofolate reductase1.5.1.30.458
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.458
2bkzSBCCyclin-dependent kinase 22.7.11.220.458
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.458
2q7gCCLPyrrolysine--tRNA ligase/0.458
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.458
3a0tADPSensor histidine kinase/0.458
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
3flwFLWMitogen-activated protein kinase 14/0.458
3fskRO6Mitogen-activated protein kinase 14/0.458
3r0iC0K1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.458
3rk507ZCyclin-dependent kinase 22.7.11.220.458
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.458
4djqM86Pol polyprotein/0.458
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.458
4jq7KJQEpidermal growth factor receptor2.7.10.10.458
4l49CAMCamphor 5-monooxygenase1.14.15.10.458
1kceCB3Thymidylate synthase/0.457
1tj0FADBifunctional protein PutA1.5.5.20.457
2c6iDT1Cyclin-dependent kinase 22.7.11.220.457
2hog710Serine/threonine-protein kinase Chk12.7.11.10.457
2i0aMUIProtease/0.457
2j2pSC2Ficolin-2/0.457
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.457
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.457
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.457
2pulACPMethylthioribose kinase2.7.1.1000.457
2qtvGNPSmall COPII coat GTPase SAR13.6.50.457
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.457
3cwkREACellular retinoic acid-binding protein 2/0.457
3i6oGR6Gag-Pol polyprotein3.4.23.160.457
4kip1R9Mitogen-activated protein kinase 14/0.457
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.457
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.457
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.456
1vyw292Cyclin-dependent kinase 22.7.11.220.456
1w7iADPUnconventional myosin-Va/0.456
1zys199Serine/threonine-protein kinase Chk12.7.11.10.456
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.456
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.456
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.456
2hckQUETyrosine-protein kinase HCK2.7.10.20.456
2i4vDJRV-1 protease/0.456
2izrBRKCasein kinase I isoform gamma-32.7.11.10.456
2p83MR0Beta-secretase 13.4.23.460.456
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.456
2zbaZBATrichothecene 3-O-acetyltransferase/0.456
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3c50ADPRhodopsin kinase/0.456
3w551FMMitogen-activated protein kinase 12.7.11.240.456
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4dqh017Gag-Pol polyprotein/0.456
4eh6IRGMitogen-activated protein kinase 14/0.456
4fkpLS5Cyclin-dependent kinase 22.7.11.220.456
4fkw62KCyclin-dependent kinase 22.7.11.220.456
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.456
4ivb1J5Tyrosine-protein kinase JAK1/0.456
4kbc1QJCasein kinase I isoform delta2.7.11.10.456
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.456
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.456
3pblETQD(3) dopamine receptor/0.456
1eh4IC1Casein kinase I homolog 12.7.11.10.455
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.455
1nzdUPGDNA beta-glucosyltransferase/0.455
2hf8GSPProbable hydrogenase nickel incorporation protein HypB/0.455
2pmnK51Protein kinase 7/0.455
2psuMUUProtease/0.455
2qi3MZ5Gag-Pol polyprotein/0.455
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.455
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.455
2xa4AZ5Tyrosine-protein kinase JAK2/0.455
3fwiCAMCamphor 5-monooxygenase1.14.15.10.455
3nf8CDQGag-Pol polyprotein/0.455
3nmpPYVAbscisic acid receptor PYL2/0.455
3nxe2NCProtease/0.455
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.455
3sacAF8Protease/0.455
3w32W32Epidermal growth factor receptor2.7.10.10.455
4ewhT77Activated CDC42 kinase 1/0.455
4foc0UUALK tyrosine kinase receptor2.7.10.10.455
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.455
4jhz1KVBeta-glucuronidase3.2.1.310.455
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.455
1f5nGNPGuanylate-binding protein 1/0.454
1iwiCAMCamphor 5-monooxygenase1.14.15.10.454
1llwFMNFerredoxin-dependent glutamate synthase 21.4.7.10.454
1q0bNATKinesin-like protein KIF11/0.454
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.454
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.454
1t3r017Gag-Pol polyprotein3.4.23.160.454
1t85CAMCamphor 5-monooxygenase1.14.15.10.454
1trgCB3Thymidylate synthase/0.454
1v0pPVBCell division control protein 2 homolog2.7.11.220.454
2f2uM77Rho-associated protein kinase 22.7.11.10.454
2pmoHMDProtein kinase 7/0.454
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.454
2rkvZBATrichothecene 3-O-acetyltransferase/0.454
2uxiG50HTH-type transcriptional regulator TtgR/0.454
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.454
3ac1KZITyrosine-protein kinase Lck2.7.10.20.454
3adaNADSubunit alpha of sarocosine oxidase/0.454
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3fmkFMKMitogen-activated protein kinase 14/0.454
3fwsANPTranscriptional repressor CcpN/0.454
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3mxdK53Gag-Pol polyprotein3.4.23.160.454
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.454
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.454
4g2fC07Ephrin type-A receptor 32.7.10.10.454
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.454
4ivd15TTyrosine-protein kinase JAK1/0.454
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1fwkADPHomoserine kinase2.7.1.390.453
1g4tFTPThiamine-phosphate synthase/0.453
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1k7fIAVTryptophan synthase alpha chain/0.453
1nhhANPDNA mismatch repair protein MutL/0.453
1s14NOVDNA topoisomerase 4 subunit B/0.453
1sbgIM1Gag-Pol polyprotein/0.453
2a1nCAMCamphor 5-monooxygenase1.14.15.10.453
2bfyH1NAurora kinase B-A2.7.11.10.453
2cciATPCyclin-dependent kinase 22.7.11.220.453
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.453
2ittAEEEpidermal growth factor receptor2.7.10.10.453
2owkSAHDiphthine synthase/0.453
2q70DC8Estrogen receptor/0.453
2qboCAMCamphor 5-monooxygenase1.14.15.10.453
2qd7065Gag-Pol polyprotein3.4.23.160.453
2vhzNAIAlanine dehydrogenase1.4.1.10.453
2webPP4Penicillopepsin-13.4.23.200.453
2xneASHAurora kinase A2.7.11.10.453
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.453
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
3hyz42CHeat shock protein HSP 90-alpha/0.453
3iok1P6Tyrosine-protein kinase JAK2/0.453
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.453
3oy4017Gag-Pol polyprotein3.4.23.160.453
3sa323XProtease/0.453
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4dqb017Gag-Pol polyprotein/0.453
4erkOLOMitogen-activated protein kinase 12.7.11.240.453
4erwSTUCyclin-dependent kinase 22.7.11.220.453
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.453
4hge15VTyrosine-protein kinase JAK2/0.453
4hvg19QTyrosine-protein kinase JAK32.7.10.20.453
4kkyCAMCamphor 5-monooxygenase1.14.15.10.453
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.453
4yagNAIC alpha-dehydrogenase/0.453
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
1cx4CMPcAMP-dependent protein kinase type II-beta regulatory subunit/0.452
1dhiMTXDihydrofolate reductase1.5.1.30.452
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.452
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.452
1svmATPLarge T antigen3.6.40.452
1t86CAMCamphor 5-monooxygenase1.14.15.10.452
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.452
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.452
1yrdCAMCamphor 5-monooxygenase1.14.15.10.452
1zrzBI1Protein kinase C iota type2.7.11.130.452
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.452
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.452
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.452
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
2hs2017Protease/0.452
2huqSAHDiphthine synthase/0.452
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.452
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.452
3a60STURibosomal protein S6 kinase beta-12.7.11.10.452
3iaeD7KBenzaldehyde lyase/0.452
3l63CAMCamphor 5-monooxygenase1.14.15.10.452
3lqfNADGalactitol dehydrogenase/0.452
3o9eA60Pol polyprotein/0.452
3ormAGSSerine/threonine protein kinase/0.452
4brxKGWFocal adhesion kinase 12.7.10.20.452
4dbzNDPPutative ketoacyl reductase1.3.10.452
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.452
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.452
5auxKMPDeath-associated protein kinase 12.7.11.10.452
5dr6SKEAurora kinase A2.7.11.10.452
1h1s4SPCyclin-dependent kinase 22.7.11.220.451
1hwr216Gag-Pol polyprotein3.4.23.160.451
1jpaANPEphrin type-B receptor 22.7.10.10.451
1k2c0Q4Gag-Pol polyprotein3.4.23.160.451
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.451
1n1pFADCholesterol oxidase1.1.3.60.451
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1phhFADp-hydroxybenzoate hydroxylase/0.451
1pyePM1Cyclin-dependent kinase 22.7.11.220.451
1rv7AB1Protease/0.451
1t88CAMCamphor 5-monooxygenase1.14.15.10.451
2aaxPDNMineralocorticoid receptor/0.451
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.451
2cct2E1Heat shock protein HSP 90-alpha/0.451
2f8g017Gag-Pol polyprotein3.4.23.160.451
2fde385Gag-Pol polyprotein3.4.23.160.451
2iwxM1SATP-dependent molecular chaperone HSP82/0.451
2j7t274Serine/threonine-protein kinase 102.7.11.10.451
2uxoTACHTH-type transcriptional regulator TtgR/0.451
2wipP49Cyclin-dependent kinase 22.7.11.220.451
2xikJ60Serine/threonine-protein kinase 252.7.11.10.451
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.451
2ylzFADPhenylacetone monooxygenase1.14.13.920.451
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.451
3lctADPALK tyrosine kinase receptor2.7.10.10.451
3pwrROCGag-Pol polyprotein3.4.23.160.451
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4cggK5QIntegrase/0.451
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.451
4fv6E57Mitogen-activated protein kinase 12.7.11.240.451
4gg70J8Hepatocyte growth factor receptor2.7.10.10.451
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.451
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.451
4p6wMOFGlucocorticoid receptor/0.451
1bdrIM1Gag-Pol polyprotein3.4.23.160.450
1dhrNADDihydropteridine reductase1.5.1.340.450
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.450
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.450
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.450
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.450
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.450
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.450
2bxmIMNSerum albumin/0.450
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2ek2SAHDiphthine synthase/0.450
2itvANPEpidermal growth factor receptor2.7.10.10.450
2m56CAMCamphor 5-monooxygenase1.14.15.10.450
2nnpROCProtease/0.450
2q46NAPUncharacterized protein At5g02240/0.450
2rg6287Mitogen-activated protein kinase 14/0.450
2xjgXJGHeat shock protein HSP 90-alpha/0.450
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.450
3anxMTAPolyamine aminopropyltransferase/0.450
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.450
3bhtMFRCyclin-dependent kinase 22.7.11.220.450
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.450
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
3kbz2T4Fructose-1,6-bisphosphatase 13.1.3.110.450
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.450
3t8vBTJM1 family aminopeptidase3.4.110.450
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.450
4gaeNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.450
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.450
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.450
1cqp803Integrin alpha-L/0.449
1dz8CAMCamphor 5-monooxygenase1.14.15.10.449
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.449
1kzjCB3Thymidylate synthase/0.449
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.449
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.449
1pdhFASp-hydroxybenzoate hydroxylase/0.449
1rx8NAPDihydrofolate reductase1.5.1.30.449
1u2yGOXPancreatic alpha-amylase/0.449
1w2xRCPAcetyl-CoA carboxylase/0.449
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.449
2ckeIQUDeath-associated protein kinase 2/0.449
2dsgSAHDiphthine synthase/0.449
2ituITQEpidermal growth factor receptor2.7.10.10.449
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.449
2uzlC94Cyclin-dependent kinase 22.7.11.220.449
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2z97CAMCamphor 5-monooxygenase1.14.15.10.449
3a3bRBFLumazine protein/0.449
3d1xROCGag-Pol polyprotein3.4.23.160.449
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.449
3ekwDR7Gag-Pol polyprotein3.4.23.160.449
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.449
3ibqATPPyridoxal kinase/0.449
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.449
3mpt1GKMitogen-activated protein kinase 14/0.449
3o9cK20Pol polyprotein/0.449
3o9dK19Pol polyprotein/0.449
3oroAGSSerine/threonine protein kinase/0.449
3q9wEMOCasein kinase II subunit alpha2.7.11.10.449
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.449
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.449
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.449
4fv9E71Mitogen-activated protein kinase 12.7.11.240.449
4g1wG1WMitogen-activated protein kinase 82.7.11.240.449
4k6fNAPPutative Acetoacetyl-CoA reductase/0.449
4kiq1RAMitogen-activated protein kinase 14/0.449
4lyn1YGCyclin-dependent kinase 22.7.11.220.449
4xivACPChemotaxis protein CheA2.7.13.30.449
4y93746Tyrosine-protein kinase/0.449
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.449
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1nooCAHCamphor 5-monooxygenase1.14.15.10.448
1p0pBCHCholinesterase3.1.1.80.448
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.448
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.448
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.448
2ew5Y12Peptide deformylase/0.448
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.448
2iorADPChaperone protein HtpG/0.448
2iwsNP4ATP-dependent molecular chaperone HSP82/0.448
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2wxvWXVCyclin-dependent kinase 22.7.11.220.448
3eqlMXPDNA-directed RNA polymerase subunit beta/0.448
3eqlMXPDNA-directed RNA polymerase subunit beta'/0.448
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.448
3fwgCAMCamphor 5-monooxygenase1.14.15.10.448
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.448
3lixE17Protease/0.448
3nux3NVCyclin-dependent kinase 62.7.11.220.448
3orlAGSSerine/threonine protein kinase/0.448
4co4ATPNitrogen regulatory protein P-II 1/0.448
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.448
4ib3ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
4nj32KDCyclin-dependent kinase 22.7.11.220.448
4wucANPDNA gyrase subunit B/0.448
4xj43ATCyclic GMP-AMP synthase/0.448
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.447
1m78NDPDihydrofolate reductase1.5.1.30.447
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1wvxBD4Death-associated protein kinase 12.7.11.10.447
1yinCM3Estrogen receptor/0.447
1yrcCAMCamphor 5-monooxygenase1.14.15.10.447
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.447
2avvMK1Gag-Pol polyprotein3.4.23.160.447
2hl1A3SThreonine--tRNA ligase6.1.1.30.447
2hv9SFGmRNA cap guanine-N7 methyltransferase2.1.1.560.447
2iehMOYKinesin-like protein KIF11/0.447
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.447
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.447
2xjxXJXHeat shock protein HSP 90-alpha/0.447
2z4y252Geranylgeranyl pyrophosphate synthase/0.447
3bv3P39Mitogen-activated protein kinase 14/0.447
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3ix4TX1Transcriptional activator protein LasR/0.447
3n0tOPYDipeptidyl peptidase 23.4.14.20.447
3nbwTR4Ketohexokinase/0.447
3o8tBMUMitogen-activated protein kinase 14/0.447
3o9fK2DGag-Pol polyprotein/0.447
3rfxNADUronate dehydrogenase/0.447
3sh25DRDihydrofolate reductase1.5.1.30.447
3ucb017Gag-Pol polyprotein/0.447
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.447
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.447
4dkv0KWEnvelope glycoprotein gp160/0.447
4ek1CAMCamphor 5-monooxygenase1.14.15.10.447
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.447
4gk3L87Ephrin type-A receptor 32.7.10.10.447
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.447
4looSB4Mitogen-activated protein kinase 14/0.447
4m6jNDPDihydrofolate reductase1.5.1.30.447
4mgiCMPRap guanine nucleotide exchange factor 4/0.447
4nh82LCHeat shock protein HSP 90-alpha/0.447
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.447
4rnhC2EMotility regulator/0.447
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.447
1dr2TAPDihydrofolate reductase1.5.1.30.446
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.446
1g69TZPThiamine-phosphate synthase/0.446
1g6cIFPThiamine-phosphate synthase/0.446
1h0w207Cyclin-dependent kinase 22.7.11.220.446
1ia1NDPDihydrofolate reductase1.5.1.30.446
1pr9NAPL-xylulose reductase1.1.1.100.446
1qpbTPPPyruvate decarboxylase isozyme 1/0.446
1xkdNAPIsocitrate dehydrogenase [NADP]/0.446
1y0s331Peroxisome proliferator-activated receptor delta/0.446
2cvwGDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.446
2f80017Gag-Pol polyprotein3.4.23.160.446
2gr1FADFerredoxin reductase/0.446
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.446
3c13EMOCasein kinase II subunit alpha2.7.11.10.446
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.446
3ekqROCGag-Pol polyprotein3.4.23.160.446
3gi4K60Gag-Pol polyprotein/0.446
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.446
3l8xN4DMitogen-activated protein kinase 14/0.446
3pd2A3SThreonine--tRNA ligase6.1.1.30.446
3w33W19Epidermal growth factor receptor2.7.10.10.446
3wrhCAMCamphor 5-monooxygenase1.14.15.10.446
4ce3L4VATP-dependent molecular chaperone HSP82/0.446
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.446
4ib4ERM5-hydroxytryptamine receptor 2B/0.446
4oaeCLMUncharacterized protein/0.446
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.446
4u0mGTPCyclic GMP-AMP synthase/0.446
1cs4FOKAdenylate cyclase type 2/0.445
1cs4FOKAdenylate cyclase type 5/0.445
1drhNAPDihydrofolate reductase1.5.1.30.445
1e9hINRCyclin-dependent kinase 22.7.11.220.445
1jhrP2PNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.445
1l4hNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.445
1p2a5BNCyclin-dependent kinase 22.7.11.220.445
1sxjAGSReplication factor C subunit 1/0.445
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1zeoC01Peroxisome proliferator-activated receptor gamma/0.445
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2bujSTUSerine/threonine-protein kinase 16/0.445
2cdaNAPGlucose 1-dehydrogenase/0.445
2i4xKGQProtease/0.445
2oklBB2Peptide deformylase 2/0.445
2qblCAMCamphor 5-monooxygenase1.14.15.10.445
2qi1MZ4Gag-Pol polyprotein/0.445
2vwx7X4Ephrin type-B receptor 42.7.10.10.445
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.445
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.445
3a1nNADNDP-sugar epimerase/0.445
3bqr4RBDeath-associated protein kinase 3/0.445
3eyhIZATyrosine-protein kinase JAK1/0.445
3fwjCAMCamphor 5-monooxygenase1.14.15.10.445
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3go4SAHUncharacterized protein/0.445
3hz142CHeat shock protein HSP 90-alpha/0.445
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.445
3nj0PYVAbscisic acid receptor PYL2/0.445
3pyy3YYTyrosine-protein kinase ABL12.7.10.20.445
3qihFG7Gag-Pol polyprotein3.4.23.160.445
3qqgX06Cyclin-dependent kinase 22.7.11.220.445
3vf7031Gag-Pol polyprotein3.4.23.160.445
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.445
4awp99AHeat shock protein HSP 90-alpha/0.445
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4g6oE28Mitogen-activated protein kinase 12.7.11.240.445
4gevCB3Thymidylate synthase/0.445
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.445
4l4cCAMCamphor 5-monooxygenase1.14.15.10.445
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.445
4tnbSGVG protein-coupled receptor kinase 52.7.11.160.445
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.445
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.445
5dulNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.445
4ea30NNNociceptin receptor/0.445
1bgqRDCATP-dependent molecular chaperone HSP82/0.444
1bv9XV6Gag-Pol polyprotein3.4.23.160.444
1bxoPP7Penicillopepsin-13.4.23.200.444
1dz4CAMCamphor 5-monooxygenase1.14.15.10.444
1ec3MS3Gag-Pol polyprotein3.4.23.160.444
1m2rMNYCasein kinase II subunit alpha2.7.11.10.444
1ndzFR5Adenosine deaminase3.5.4.40.444
1rfuADPPyridoxal kinase2.7.1.350.444
2br5SAHCephalosporin hydroxylase CmcI/0.444
2cig1DGDihydrofolate reductase1.5.1.30.444
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.444
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.444
2q61SF1Peroxisome proliferator-activated receptor gamma/0.444
2xvq9DSSerum albumin/0.444
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.444
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.444
2zaxCAMCamphor 5-monooxygenase1.14.15.10.444
3d0bSNXHeat shock protein HSP 90-alpha/0.444
3ekv478Gag-Pol polyprotein3.4.23.160.444
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.444
3oafOAGDihydrofolate reductase1.5.1.30.444
3vf80JETyrosine-protein kinase SYK2.7.10.20.444
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.444
4b99R4LMitogen-activated protein kinase 72.7.11.240.444
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.444
4eomATPCyclin-dependent kinase 22.7.11.220.444
4gmy0X5Tyrosine-protein kinase JAK2/0.444
4ibmIR1Insulin receptor2.7.10.10.444
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.444
4j97ACPFibroblast growth factor receptor 2/0.444
4jajXU1Aurora kinase A2.7.11.10.444
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4o671SYCyclic GMP-AMP synthase/0.444
4qmpDKISerine/threonine-protein kinase 242.7.11.10.444
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.444
1ae8AZLProthrombin3.4.21.50.443
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1f20FADNitric oxide synthase, brain1.14.13.390.443
1klkPMDDihydrofolate reductase1.5.1.30.443
1mezGDPAdenylosuccinate synthetase isozyme 1/0.443
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.443
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.443
1sguMK1Gag-Pol polyprotein3.4.23.160.443
2bpv1INGag-Pol polyprotein3.4.23.160.443
2bpz3INGag-Pol polyprotein3.4.23.160.443
2c5nCK8Cyclin-dependent kinase 22.7.11.220.443
2gqpPA7Endoplasmin/0.443
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.443
2izt23DCasein kinase I isoform gamma-32.7.11.10.443
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.443
2j5xGSPADP-ribosylation factor 6/0.443
2pdtFADVivid PAS protein VVD/0.443
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.443
2rh9IGPTryptophan synthase alpha chain/0.443
2wi6ZZ6Heat shock protein HSP 90-alpha/0.443
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.443
2znq401Peroxisome proliferator-activated receptor delta/0.443
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.443
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.443
3e8r615Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.443
3el01UNGag-Pol polyprotein3.4.23.160.443
3f7bAG5Carbonic anhydrase 44.2.1.10.443
3hllI45Mitogen-activated protein kinase 14/0.443
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.443
3i60E86Mitogen-activated protein kinase 12.7.11.240.443
3lxiCAMCytochrome P450/0.443
3pxkPXKFocal adhesion kinase 12.7.10.20.443
3qziX72Cyclin-dependent kinase 22.7.11.220.443
3sqq99ZCyclin-dependent kinase 22.7.11.220.443
3zdu38RCyclin-dependent kinase-like 32.7.11.220.443
4a9iP9IBromodomain-containing protein 2/0.443
4aotGW8Serine/threonine-protein kinase 102.7.11.10.443
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
4ccbOFGALK tyrosine kinase receptor2.7.10.10.443
4egbNADdTDP-glucose 4,6-dehydratase/0.443
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.443
4fxy0W2Neurolysin, mitochondrial3.4.24.160.443
4l4eCAMCamphor 5-monooxygenase1.14.15.10.443
4nks2M2Fibroblast growth factor receptor 1/0.443
1a8g2Z4Gag-Pol polyprotein3.4.23.160.442
1cbqRE9Cellular retinoic acid-binding protein 2/0.442
1g41ADPATP-dependent protease ATPase subunit HslU/0.442
1gij2PUCyclin-dependent kinase 22.7.11.220.442
1hiv1ZKGag-Pol polyprotein/0.442
1hosPHPGag-Pol polyprotein/0.442
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.442
1j39UPGDNA beta-glucosyltransferase/0.442
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.442
1mg5NAIAlcohol dehydrogenase1.1.1.10.442
1qbu846Gag-Pol polyprotein3.4.23.160.442
1rw8580TGF-beta receptor type-12.7.11.300.442
1rx8FOLDihydrofolate reductase1.5.1.30.442
1u33LM2Pancreatic alpha-amylase/0.442
1wbmBLLPol protein/0.442
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.442
2a1oCAMCamphor 5-monooxygenase1.14.15.10.442
2a3iC0RMineralocorticoid receptor/0.442
2aa71CAMineralocorticoid receptor/0.442
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.442
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.442
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2e7zMGDAcetylene hydratase/0.442
2nmyROCProtease/0.442
2p1u4TNRetinoic acid receptor RXR-alpha/0.442
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2wgjVGHHepatocyte growth factor receptor2.7.10.10.442
2x0rNADMalate dehydrogenase/0.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.442
2yn8STUEphrin type-B receptor 42.7.10.10.442
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.442
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.442
3iw4LW4Protein kinase C alpha type2.7.11.130.442
3jpuTY4Transcriptional activator protein LasR/0.442
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3rf7NADIron-containing alcohol dehydrogenase/0.442
3sa4F72Protease/0.442
3w0c6DSVitamin D3 receptor/0.442
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.442
4b8lA0PAurora kinase B-A2.7.11.10.442
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.442
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.442
4hvh19RTyrosine-protein kinase JAK32.7.10.20.442
4i22IREEpidermal growth factor receptor2.7.10.10.442
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.442
4jnqFDAThioredoxin reductase/0.442
4kh0ATPAspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002}/0.442
4lopSB4Mitogen-activated protein kinase 14/0.442
4mpcPV2[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.442
4qecNAPElxO/0.442
4wkqIREEpidermal growth factor receptor2.7.10.10.442
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5e8wSTUTGF-beta receptor type-12.7.11.300.442
1bdlIM1Gag-Pol polyprotein3.4.23.160.441
1idb0DOGag-Pol polyprotein/0.441
1l5l7RPNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.441
1pxpCK8Cyclin-dependent kinase 22.7.11.220.441
1u4dDBQActivated CDC42 kinase 1/0.441
1um8ADPATP-dependent Clp protease ATP-binding subunit ClpX/0.441
1uy7PU4Heat shock protein HSP 90-alpha/0.441
1wvySTUDeath-associated protein kinase 12.7.11.10.441
1z1rHBHGag-Pol polyprotein3.4.23.160.441
2cbrA80Cellular retinoic acid-binding protein 1/0.441
2hl2SSAThreonine--tRNA ligase6.1.1.30.441
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
2j0m4STFocal adhesion kinase 12.7.10.20.441
2jedLG8Protein kinase C theta type2.7.11.130.441
2p7zOHTEstrogen-related receptor gamma/0.441
2q55MU0Protease/0.441
2qo7ANPEphrin type-A receptor 32.7.10.10.441
2yee2ECHeat shock protein HSP 90-alpha/0.441
3da1FADGlycerol-3-phosphate dehydrogenase/0.441
3i0rRT3Gag-Pol polyprotein2.7.7.490.441
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3lm9ADPPutative fructokinase2.7.1.40.441
3mdmFJZCholesterol 24-hydroxylase/0.441
3o9gF53Gag-Pol polyprotein/0.441
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.441
3rps4B0Casein kinase II subunit alpha2.7.11.10.441
3vjnANPEpidermal growth factor receptor2.7.10.10.441
3zuxTCHTransporter/0.441
4affATPNitrogen regulatory protein P-II/0.441
4anbYQYDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.441
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.441
4c4jX21Dual specificity protein kinase TTK2.7.12.10.441
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.441
4dqc017Gag-Pol polyprotein/0.441
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.441
4egkRDCHeat shock protein HSP 90-alpha/0.441
4eh3NARMitogen-activated protein kinase 14/0.441
4f630S7Fibroblast growth factor receptor 1/0.441
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.441
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.441
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.441
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.441
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.441
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.441
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.441
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.441
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.441
4j55031Gag-Pol polyprotein3.4.23.160.441
4k4p3TLGag-Pol polyprotein/0.441
4k8aK8AFocal adhesion kinase 12.7.10.20.441
4kba1QMCasein kinase I isoform delta2.7.11.10.441
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.441
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.441
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.441
5fwnNAPPutative dehydrogenase/0.441
1g67TZPThiamine-phosphate synthase/0.440
1gebCAMCamphor 5-monooxygenase1.14.15.10.440
1jtuLYBThymidylate synthase/0.440
1k6vXN2Gag-Pol polyprotein3.4.23.160.440
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.440
1mtrPI6Gag-Pol polyprotein3.4.23.160.440
1o76CAMCamphor 5-monooxygenase1.14.15.10.440
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.440
1t7j478Gag-Pol polyprotein3.4.23.160.440
1unlRRCCyclin-dependent-like kinase 52.7.11.10.440
1yt9OISGag-Pol polyprotein/0.440
1z1fSTLResveratrol synthase/0.440
2aa2AS4Mineralocorticoid receptor/0.440
2bpy3INGag-Pol polyprotein3.4.23.160.440
2cvjFADThioredoxin reductase related protein/0.440
2pklDHTAndrogen receptor/0.440
2pym1UNGag-Pol polyprotein3.4.23.160.440
2q7vFADThioredoxin reductase/0.440
2qbmCAMCamphor 5-monooxygenase1.14.15.10.440
2qi5MZ7Gag-Pol polyprotein/0.440
2wi2ZZ3Heat shock protein HSP 90-alpha/0.440
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.440
2wouZZFTGF-beta receptor type-12.7.11.300.440
2x4zX4ZSerine/threonine-protein kinase PAK 42.7.11.10.440
2xyeCXGGag-Pol polyprotein/0.440
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.440
3fi4FI4Mitogen-activated protein kinase 14/0.440
3kc12T6Fructose-1,6-bisphosphatase 13.1.3.110.440
3lpiZ74Beta-secretase 13.4.23.460.440
3n6nBUPGenome polyprotein/0.440
3nszANPCasein kinase II subunit alpha2.7.11.10.440
3q5kD1UHeat shock protein 83-1/0.440
3qqkX02Cyclin-dependent kinase 22.7.11.220.440
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.440
3t3r9PLCytochrome P450 2A61.14.130.440
3v1nHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.440
3zuyTCHTransporter/0.440
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.440
4c9oCAMCytochrome P450/0.440
4ebfNADPhosphonate dehydrogenase1.20.1.10.440
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.440
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.440
4g8zTOPDihydrofolate reductase1.5.1.30.440
4hnf16WCasein kinase I isoform delta2.7.11.10.440
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.440
4ix4ADPUncharacterized protein/0.440
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.440
4lb2DM5Serum albumin/0.440
4s32ANPMitogen-activated protein kinase 12.7.11.240.440
4y9qC2EUncharacterized protein/0.440