sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zbd | GTP | Ras-related protein Rab-3A |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1zbd | GTP | Ras-related protein Rab-3A | / | 1.000 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.581 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.546 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.536 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.534 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.531 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.519 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.515 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.513 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.510 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.509 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.506 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.505 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.505 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.499 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.497 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.490 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.489 | |
| 3oiu | GNP | GTPase HRas | / | 0.487 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.487 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.487 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.486 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.486 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.484 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.480 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.480 | |
| 3ddc | GNP | GTPase HRas | / | 0.476 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.473 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.472 | |
| 4dlt | GNP | GTPase HRas | / | 0.470 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.469 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.468 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.467 | |
| 4nyj | GNP | GTPase HRas | / | 0.467 | |
| 3oiv | GNP | GTPase HRas | / | 0.464 | |
| 3lbn | GNP | GTPase HRas | / | 0.463 | |
| 3v4f | GNP | GTPase HRas | / | 0.463 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.462 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.461 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.458 | |
| 4mit | GTP | Rho-related protein racC | / | 0.458 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.457 | |
| 1lfd | GNP | GTPase HRas | / | 0.455 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.455 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.454 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.454 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.450 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.450 | |
| 3i3s | GNP | GTPase HRas | / | 0.446 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.442 | |
| 5b2z | GNP | GTPase HRas | / | 0.442 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.441 |