sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1yzq | GNP | Ras-related protein Rab-6A |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1yzq | GNP | Ras-related protein Rab-6A | / | 1.000 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.626 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.615 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.601 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.591 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.589 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.581 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.565 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.549 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.546 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.544 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.536 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.521 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.519 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.508 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.507 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.505 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.498 | |
| 3lbn | GNP | GTPase HRas | / | 0.492 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.491 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.490 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.488 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.488 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.487 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.487 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.482 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.480 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.477 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.476 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.475 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.474 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.472 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.472 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.468 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.467 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.467 | |
| 3v4f | GNP | GTPase HRas | / | 0.466 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.466 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.464 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.463 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.461 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.461 | |
| 3oiu | GNP | GTPase HRas | / | 0.461 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.460 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.456 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.454 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.454 | |
| 5b2z | GNP | GTPase HRas | / | 0.451 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 3rs5 | GNP | GTPase HRas | / | 0.449 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.447 | |
| 3oiv | GNP | GTPase HRas | / | 0.446 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.444 | |
| 3ddc | GNP | GTPase HRas | / | 0.444 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.443 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.442 | |
| 4nyj | GNP | GTPase HRas | / | 0.442 |