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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1yv5RISFarnesyl pyrophosphate synthase2.5.1.10

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1yv5RISFarnesyl pyrophosphate synthase2.5.1.101.000
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.581
4q23RISFarnesyl pyrophosphate synthase2.5.1.100.529
2f94BFQFarnesyl pyrophosphate synthase2.5.1.100.484
4lfvYS4Farnesyl pyrophosphate synthase2.5.1.100.464
3rbmB73Farnesyl pyrophosphate synthase, putative/0.461
3ryeUNRFarnesyl pyrophosphate synthase2.5.1.100.454
3ldwIPEFarnesyl pyrophosphate synthase, putative/0.445
4nkeRISFarnesyl pyrophosphate synthase2.5.1.100.444