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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.11.000
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.675
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.668
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.661
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.658
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.637
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.634
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.624
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.623
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.621
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.621
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.619
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.618
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.615
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.612
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.603
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.602
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.598
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.594
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.591
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.590
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.587
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.585
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.584
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.574
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.572
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.572
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.570
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.569
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.566
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.566
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.566
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.565
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.557
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.557
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.556
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.556
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.554
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.552
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.551
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.551
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.550
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.549
4i22IREEpidermal growth factor receptor2.7.10.10.542
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.537
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.535
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.534
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.531
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.529
4bgg844Activin receptor type-12.7.11.300.519
4othDRNSerine/threonine-protein kinase N1/0.519
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.518
1xjdSTUProtein kinase C theta type2.7.11.130.512
3umw596Serine/threonine-protein kinase pim-12.7.11.10.509
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.508
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.507
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.507
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.507
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.505
3iw4LW4Protein kinase C alpha type2.7.11.130.504
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.504
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.503
2jedLG8Protein kinase C theta type2.7.11.130.502
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
4wboANWRhodopsin kinase/0.501
3gubGUBDeath-associated protein kinase 12.7.11.10.500
4fnyI3KALK tyrosine kinase receptor2.7.10.10.500
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.497
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.495
3oom507Activin receptor type-12.7.11.300.494
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.494
1pkdUCNCyclin-dependent kinase 22.7.11.220.493
2pvnP63Casein kinase II subunit alpha2.7.11.10.493
3uyt0CKCasein kinase I isoform delta2.7.11.10.493
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.493
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.492
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.492
4riyADPEpidermal growth factor receptor2.7.10.10.492
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.491
4dymIYZActivin receptor type-12.7.11.300.491
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.491
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.490
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.490
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.489
3q9xEMOCasein kinase II subunit alpha2.7.11.10.489
2j0m4STFocal adhesion kinase 12.7.10.20.488
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.488
4grb0XGCasein kinase II subunit alpha2.7.11.10.488
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.488
3a4pDFQHepatocyte growth factor receptor2.7.10.10.487
4dgo0JWCasein kinase II subunit alpha2.7.11.10.487
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.486
2wihP48Cyclin-dependent kinase 22.7.11.220.486
1h1s4SPCyclin-dependent kinase 22.7.11.220.485
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.484
3hllI45Mitogen-activated protein kinase 14/0.484
4bchT7ZCyclin-dependent kinase 92.7.11.220.484
5cvhADPCasein kinase II subunit alpha2.7.11.10.484
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.483
2iw84SPCyclin-dependent kinase 22.7.11.220.482
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.482
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.482
4dgnLU2Casein kinase II subunit alpha2.7.11.10.482
4gmy0X5Tyrosine-protein kinase JAK2/0.482
4yuqKS1Calmodulin-like domain protein kinase/0.482
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.481
3u4uLNHCasein kinase II subunit alpha2.7.11.10.481
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.481
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.480
1aq1STUCyclin-dependent kinase 22.7.11.220.479
4anmWULCasein kinase II subunit alpha2.7.11.10.479
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.479
1wvxBD4Death-associated protein kinase 12.7.11.10.478
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.478
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.478
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.477
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.477
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.476
3mtfA3FActivin receptor type-12.7.11.300.476
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.476
4gu94GUFocal adhesion kinase 12.7.10.20.476
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.476
5av2KMPDeath-associated protein kinase 12.7.11.10.476
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.475
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.475
4c02TAKActivin receptor type-12.7.11.300.475
4gg70J8Hepatocyte growth factor receptor2.7.10.10.475
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.475
4kba1QMCasein kinase I isoform delta2.7.11.10.475
1oi9N20Cyclin-dependent kinase 22.7.11.220.474
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.474
2j0j4STFocal adhesion kinase 12.7.10.20.474
1vjy460TGF-beta receptor type-12.7.11.300.473
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.473
1x2hLPALipoate-protein ligase A6.3.1.200.472
2etm7PYFocal adhesion kinase 12.7.10.20.472
4fob0USALK tyrosine kinase receptor2.7.10.10.471
4qmzB49Serine/threonine-protein kinase 242.7.11.10.471
1yvj4STTyrosine-protein kinase JAK32.7.10.20.470
2om9AJAPeroxisome proliferator-activated receptor gamma/0.470
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.470
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.470
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.470
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.469
5auwQUEDeath-associated protein kinase 12.7.11.10.469
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1e9hINRCyclin-dependent kinase 22.7.11.220.468
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.468
1oiuN76Cyclin-dependent kinase 22.7.11.220.468
2ittAEEEpidermal growth factor receptor2.7.10.10.468
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.468
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.468
4nb6444Nuclear receptor ROR-gamma/0.468
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.467
2iw94SPCyclin-dependent kinase 22.7.11.220.467
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.467
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.467
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.467
4fod0UVALK tyrosine kinase receptor2.7.10.10.467
1bygSTUTyrosine-protein kinase CSK/0.466
1uyrD1LAcetyl-CoA carboxylase/0.466
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.466
2cchATPCyclin-dependent kinase 22.7.11.220.466
3pgqGY3Acetyl-CoA carboxylase/0.466
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.466
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.466
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.466
4jia1K3Tyrosine-protein kinase JAK2/0.466
4nc3ERM5-hydroxytryptamine receptor 2B/0.466
1eh4IC1Casein kinase I homolog 12.7.11.10.465
1m2pHNACasein kinase II subunit alpha2.7.11.10.465
1oiyN41Cyclin-dependent kinase 22.7.11.220.465
1zys199Serine/threonine-protein kinase Chk12.7.11.10.465
2i40BLZCyclin-dependent kinase 22.7.11.220.465
3bqr4RBDeath-associated protein kinase 3/0.465
3bu5ATPInsulin receptor2.7.10.10.465
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.465
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.465
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.465
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.465
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.464
1u4dDBQActivated CDC42 kinase 1/0.464
2h96893Mitogen-activated protein kinase 82.7.11.240.464
2vagV25Dual specificity protein kinase CLK12.7.12.10.464
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.464
3vt7VDXVitamin D3 receptor/0.464
4iarERM5-hydroxytryptamine receptor 1B/0.464
2x1nX1NCyclin-dependent kinase 22.7.11.220.463
3zxtACPDeath-associated protein kinase 12.7.11.10.463
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.463
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.462
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.462
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.462
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.462
3w33W19Epidermal growth factor receptor2.7.10.10.462
4erwSTUCyclin-dependent kinase 22.7.11.220.462
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.462
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
5auvAGIDeath-associated protein kinase 12.7.11.10.462
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.461
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2chlDKICasein kinase I isoform gamma-32.7.11.10.461
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.461
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.461
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.461
4hni16WCasein kinase I isoform epsilon2.7.11.10.461
4otiMI1Serine/threonine-protein kinase N1/0.461
5cshATPCasein kinase II subunit alpha2.7.11.10.461
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.460
2eufLQQCyclin-dependent kinase 62.7.11.220.460
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.460
3w18N13Aurora kinase A2.7.11.10.460
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.460
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.460
4lxhC1EAlpha/beta hydrolase fold/0.460
5auxKMPDeath-associated protein kinase 12.7.11.10.460
5e8wSTUTGF-beta receptor type-12.7.11.300.460
1lp4ANPCasein kinase II subunit alpha2.7.11.10.459
1oguST8Cyclin-dependent kinase 22.7.11.220.459
1u54ACPActivated CDC42 kinase 1/0.459
2cig1DGDihydrofolate reductase1.5.1.30.459
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.459
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.459
2uxoTACHTH-type transcriptional regulator TtgR/0.459
2znnS44Peroxisome proliferator-activated receptor alpha/0.459
3ormAGSSerine/threonine protein kinase/0.459
4eok4SPCyclin-dependent kinase 22.7.11.220.459
4g170VNCasein kinase I isoform gamma-32.7.11.10.459
4hvi19STyrosine-protein kinase JAK32.7.10.20.459
5cu6ATPCasein kinase II subunit alpha2.7.11.10.459
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1zgaHMKIsoflavone 4'-O-methyltransferase/0.458
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.458
2itpAEEEpidermal growth factor receptor2.7.10.10.458
2wedPP6Penicillopepsin-13.4.23.200.458
2zjwREFCasein kinase II subunit alpha2.7.11.10.458
3axwTIDCasein kinase II subunit alpha2.7.11.10.458
3gu6ADPDeath-associated protein kinase 12.7.11.10.458
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.458
4fx360KCyclin-dependent kinase 22.7.11.220.458
4g160VMCasein kinase I isoform gamma-32.7.11.10.458
4hvg19QTyrosine-protein kinase JAK32.7.10.20.458
4hvh19RTyrosine-protein kinase JAK32.7.10.20.458
1q1rFADPutidaredoxin reductase1.18.1.50.457
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.457
2fxdDR7Pol polyprotein/0.457
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.457
2pvlP55Casein kinase II subunit alpha2.7.11.10.457
2xa4AZ5Tyrosine-protein kinase JAK2/0.457
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.457
3uli1N3Cyclin-dependent kinase 22.7.11.220.457
3vf9477Tyrosine-protein kinase SYK2.7.10.20.457
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.457
4kbk1QGCasein kinase I isoform delta2.7.11.10.457
5av4GENDeath-associated protein kinase 12.7.11.10.457
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.456
2uzlC94Cyclin-dependent kinase 22.7.11.220.456
2w1fL0FAurora kinase A2.7.11.10.456
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.456
3gc9B45Mitogen-activated protein kinase 112.7.11.240.456
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3r9dX6BCyclin-dependent kinase 22.7.11.220.456
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.456
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.456
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.456
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.456
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.455
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.455
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.455
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.455
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.455
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.455
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.455
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.455
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4b4oNDPEpimerase family protein SDR39U1/0.455
4b99R4LMitogen-activated protein kinase 72.7.11.240.455
4bbe3O4Tyrosine-protein kinase JAK2/0.455
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.455
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.454
2xikJ60Serine/threonine-protein kinase 252.7.11.10.454
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.454
3kxw1ZZSaframycin Mx1 synthetase B/0.454
2b52D42Cyclin-dependent kinase 22.7.11.220.453
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.453
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.453
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3blrCPBCyclin-dependent kinase 92.7.11.220.453
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
3livE16Protease/0.453
3qj5022Alcohol dehydrogenase class-31.1.1.10.453
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.453
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.453
4eon1ROCyclin-dependent kinase 22.7.11.220.453
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.453
4jboWPHAurora kinase A2.7.11.10.453
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.453
4qmpDKISerine/threonine-protein kinase 242.7.11.10.453
1fmjRTLRetinol dehydratase/0.452
1gih1PUCyclin-dependent kinase 22.7.11.220.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.452
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.452
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.452
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.452
3oafOAGDihydrofolate reductase1.5.1.30.452
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.452
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
3ttjJBIMitogen-activated protein kinase 102.7.11.240.452
3zh8C58Protein kinase C iota type2.7.11.130.452
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3zze6XPHepatocyte growth factor receptor2.7.10.10.452
4eoi1ROCyclin-dependent kinase 22.7.11.220.452
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.452
4ib4ERM5-hydroxytryptamine receptor 2B/0.452
4ic7ANPMitogen-activated protein kinase 72.7.11.240.452
4lopSB4Mitogen-activated protein kinase 14/0.452
5auuLU2Death-associated protein kinase 12.7.11.10.452
5f0a1FBcGMP-dependent protein kinase, putative/0.452
1qxlFR8Adenosine deaminase3.5.4.40.451
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2hog710Serine/threonine-protein kinase Chk12.7.11.10.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
2xnbY8LCyclin-dependent kinase 22.7.11.220.451
2znq401Peroxisome proliferator-activated receptor delta/0.451
3t8oATPRhodopsin kinase/0.451
3vt8YI3Vitamin D3 receptor/0.451
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.451
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1p4fDRGDeath-associated protein kinase 12.7.11.10.450
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
3a60STURibosomal protein S6 kinase beta-12.7.11.10.450
3be9P04Casein kinase II subunit alpha2.7.11.10.450
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.450
3oroAGSSerine/threonine protein kinase/0.450
3s1dZIRCytokinin dehydrogenase 11.5.99.120.450
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1m2qMNXCasein kinase II subunit alpha2.7.11.10.449
1m2rMNYCasein kinase II subunit alpha2.7.11.10.449
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
2izrBRKCasein kinase I isoform gamma-32.7.11.10.449
2pvhP19Casein kinase II subunit alpha2.7.11.10.449
3a62STURibosomal protein S6 kinase beta-12.7.11.10.449
3gwfFADCyclohexanone monooxygenase/0.449
3kf7L9GMitogen-activated protein kinase 14/0.449
3nglNAPBifunctional protein FolD/0.449
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.449
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.449
4jqeANPCasein kinase II subunit alpha2.7.11.10.449
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
2a0cCK9Cyclin-dependent kinase 22.7.11.220.448
3so9017Pol protein/0.448
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.448
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.448
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.448
4e730NRMitogen-activated protein kinase 82.7.11.240.448
4f630S7Fibroblast growth factor receptor 1/0.448
4hgs15GCasein kinase I isoform gamma-32.7.11.10.448
4nk92K5Fibroblast growth factor receptor 1/0.448
1d2sDHTSex hormone-binding globulin/0.447
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.447
2ev9NAPShikimate dehydrogenase (NADP(+))/0.447
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.447
3at3ATKCasein kinase II subunit alpha2.7.11.10.447
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.447
3litE15Protease/0.447
3mdvCL6Cholesterol 24-hydroxylase/0.447
3mtlFEFCyclin-dependent kinase 162.7.11.220.447
3nynSGVG protein-coupled receptor kinase 62.7.11.160.447
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.447
3vt9YI4Vitamin D3 receptor/0.447
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jq8KJ8Epidermal growth factor receptor2.7.10.10.447
1bai0Q4Gag-Pro polyprotein/0.446
1g5sI17Cyclin-dependent kinase 22.7.11.220.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.446
2ijmADPFocal adhesion kinase 12.7.10.20.446
2p33J07Mitogen-activated protein kinase 102.7.11.240.446
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.446
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.446
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.446
3q9zTXQCasein kinase II subunit alpha2.7.11.10.446
3rps4B0Casein kinase II subunit alpha2.7.11.10.446
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.446
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.446
4jbpYPHAurora kinase A2.7.11.10.446
4wsqKSAAP2-associated protein kinase 12.7.11.10.446
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.445
2po7CHDFerrochelatase, mitochondrial4.99.1.10.445
2uxuNARHTH-type transcriptional regulator TtgR/0.445
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.445
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.445
3lixE17Protease/0.445
3rni21ZCyclin-dependent kinase 22.7.11.220.445
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.445
4c4f7CEDual specificity protein kinase TTK2.7.12.10.445
4c4g7RODual specificity protein kinase TTK2.7.12.10.445
4dgmAGICasein kinase II subunit alpha2.7.11.10.445
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.445
4fyn0VETyrosine-protein kinase SYK2.7.10.20.445
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
5av3KMPDeath-associated protein kinase 12.7.11.10.445
5bmvVLBTubulin alpha-1B chain/0.445
5bmvVLBTubulin beta chain/0.445
5e8ySTUTGF-beta receptor type-22.7.11.300.445
1likADNAdenosine kinase2.7.1.200.444
1pmn984Mitogen-activated protein kinase 102.7.11.240.444
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.444
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.444
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.444
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.444
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3nga3NGCasein kinase II subunit alpha2.7.11.10.444
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.444
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.444
4kb81QNCasein kinase I isoform delta2.7.11.10.444
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.444
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.444
4wkqIREEpidermal growth factor receptor2.7.10.10.444
1g3mPCQEstrogen sulfotransferase2.8.2.40.443
1ppm0P1Penicillopepsin-13.4.23.200.443
2gr1FADFerredoxin reductase/0.443
2jkoBIJFocal adhesion kinase 12.7.10.20.443
2uxiG50HTH-type transcriptional regulator TtgR/0.443
2uzbC75Cyclin-dependent kinase 22.7.11.220.443
2uzeC95Cyclin-dependent kinase 22.7.11.220.443
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.443
3icsADPCoenzyme A disulfide reductase/0.443
3ictFADCoenzyme A disulfide reductase/0.443
3lctADPALK tyrosine kinase receptor2.7.10.10.443
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
3tubFPUTyrosine-protein kinase SYK2.7.10.20.443
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4g1wG1WMitogen-activated protein kinase 82.7.11.240.443
4gu610NFocal adhesion kinase 12.7.10.20.443
4gub0Y4Casein kinase II subunit alpha2.7.11.10.443
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1zg32HIIsoflavone 4'-O-methyltransferase/0.442
2dwbANPAurora kinase A2.7.11.10.442
2hw2RFPRifampin ADP-ribosyl transferase/0.442
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.442
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.442
2j0k4STFocal adhesion kinase 12.7.10.20.442
2wouZZFTGF-beta receptor type-12.7.11.300.442
2wpa889Cyclin-dependent kinase 22.7.11.220.442
2yboSAHMethyltransferase/0.442
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.442
3c50ADPRhodopsin kinase/0.442
3eljGS7Mitogen-activated protein kinase 82.7.11.240.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3mpaSB2Mitogen-activated protein kinase 14/0.442
3r3d4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.442
4c3yFAD3-ketosteroid dehydrogenase/0.442
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.442
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.442
4hnf16WCasein kinase I isoform delta2.7.11.10.442
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.442
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.442
5dt4ATPAurora kinase A2.7.11.10.442
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.441
1jklANPDeath-associated protein kinase 12.7.11.10.441
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.441
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.441
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.441
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.441
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.441
3at4CCKCasein kinase II subunit alpha2.7.11.10.441
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3gbuATPUncharacterized sugar kinase PH14592.7.10.441
3qqkX02Cyclin-dependent kinase 22.7.11.220.441
3rpv26ZCyclin-dependent kinase 22.7.11.220.441
3sp9IL2Peroxisome proliferator-activated receptor delta/0.441
3vetADPnebramycin 5' synthase6.1.2.20.441
3vewADPnebramycin 5' synthase6.1.2.20.441
3zewSTUEphrin type-B receptor 42.7.10.10.441
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.441
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.440
1og5SWFCytochrome P450 2C9/0.440
1umlFR4Adenosine deaminase3.5.4.40.440
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.440
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.440
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.440
2j0lANPFocal adhesion kinase 12.7.10.20.440
2jkqVG8Focal adhesion kinase 12.7.10.20.440
2yee2ECHeat shock protein HSP 90-alpha/0.440
2z7gEH9Adenosine deaminase3.5.4.40.440
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.440
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.440
4c4jX21Dual specificity protein kinase TTK2.7.12.10.440
4foc0UUALK tyrosine kinase receptor2.7.10.10.440
4iaq2GM5-hydroxytryptamine receptor 1B/0.440
4iwv1J9Glucokinase2.7.1.20.440
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440