sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1yf8	P6C	Beta-galactoside-specific lectin 4	3.2.2.22

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1yf8	P6C	Beta-galactoside-specific lectin 4	3.2.2.22	1.000
1xh7	R96	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.460
3r9u	FAD	Thioredoxin reductase	/	0.458
3f3s	NAD	Lambda-crystallin homolog	/	0.456
3wsj	MK1	Protease	/	0.455
4h3j	10W	Beta-secretase 1	3.4.23.46	0.451
3fg2	FAD	Putative rubredoxin reductase	/	0.450
1kzk	JE2	Gag-Pol polyprotein	3.4.23.16	0.449
4h8a	NAI	Ureidoglycolate dehydrogenase (NAD(+))	1.1.1.350	0.448
1r6t	TYM	Tryptophan--tRNA ligase, cytoplasmic	6.1.1.2	0.445
3liv	E16	Protease	/	0.443