sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1yc2 | APR | NAD-dependent protein deacylase 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1yc2 | APR | NAD-dependent protein deacylase 2 | / | 1.000 | |
| 1s7g | APR | NAD-dependent protein deacylase 2 | / | 0.716 | |
| 1m2h | APR | NAD-dependent protein deacylase 1 | / | 0.576 | |
| 1m2j | APR | NAD-dependent protein deacylase 1 | / | 0.560 | |
| 1m2g | APR | NAD-dependent protein deacylase 1 | / | 0.549 | |
| 1m2k | APR | NAD-dependent protein deacylase 1 | / | 0.542 | |
| 3zg6 | APR | NAD-dependent protein deacetylase sirtuin-6 | 3.5.1 | 0.525 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.509 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.484 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.460 | |
| 4iao | APR | NAD-dependent histone deacetylase SIR2 | 3.5.1 | 0.449 | |
| 5d7o | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.446 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 |