Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1y8yCT7Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1y8yCT7Cyclin-dependent kinase 22.7.11.221.000
2c6kDT2Cyclin-dependent kinase 22.7.11.220.573
3r8vZ62Cyclin-dependent kinase 22.7.11.220.569
2c6lDT4Cyclin-dependent kinase 22.7.11.220.559
2c6iDT1Cyclin-dependent kinase 22.7.11.220.535
2r3iSCFCyclin-dependent kinase 22.7.11.220.526
4fklCK2Cyclin-dependent kinase 22.7.11.220.525
2c6o4SPCyclin-dependent kinase 22.7.11.220.520
1w8cN69Cyclin-dependent kinase 22.7.11.220.518
3rahO1ZCyclin-dependent kinase 22.7.11.220.513
4fkt48KCyclin-dependent kinase 22.7.11.220.513
2b53D23Cyclin-dependent kinase 22.7.11.220.508
3qtxX43Cyclin-dependent kinase 22.7.11.220.506
3r7vZ02Cyclin-dependent kinase 22.7.11.220.505
3rm719ZCyclin-dependent kinase 22.7.11.220.504
4ek610KCyclin-dependent kinase 22.7.11.220.501
3lfqA28Cyclin-dependent kinase 22.7.11.220.499
4fki09KCyclin-dependent kinase 22.7.11.220.498
4fkq42KCyclin-dependent kinase 22.7.11.220.494
1oitHDTCyclin-dependent kinase 22.7.11.220.491
2xmyCDKCyclin-dependent kinase 22.7.11.220.489
2c6mDT5Cyclin-dependent kinase 22.7.11.220.486
4ek816KCyclin-dependent kinase 22.7.11.220.484
2a0cCK9Cyclin-dependent kinase 22.7.11.220.483
2r3jSCJCyclin-dependent kinase 22.7.11.220.483
3r71X86Cyclin-dependent kinase 22.7.11.220.483
1ykr628Cyclin-dependent kinase 22.7.11.220.482
3qwjX6ACyclin-dependent kinase 22.7.11.220.481
2btrU73Cyclin-dependent kinase 22.7.11.220.480
3r8lZ30Cyclin-dependent kinase 22.7.11.220.480
1oirHDYCyclin-dependent kinase 22.7.11.220.478
4fkpLS5Cyclin-dependent kinase 22.7.11.220.478
2exmZIPCyclin-dependent kinase 22.7.11.220.477
3r1yX76Cyclin-dependent kinase 22.7.11.220.476
2r3o2SCCyclin-dependent kinase 22.7.11.220.475
3r9nZ68Cyclin-dependent kinase 22.7.11.220.475
4kd11QKCyclin-dependent kinase 22.7.11.220.474
2vthLZ2Cyclin-dependent kinase 22.7.11.220.472
4fko20KCyclin-dependent kinase 22.7.11.220.472
2r3r6SCCyclin-dependent kinase 22.7.11.220.470
3qqlX03Cyclin-dependent kinase 22.7.11.220.470
1pxjCK2Cyclin-dependent kinase 22.7.11.220.469
3iggEFQCyclin-dependent kinase 22.7.11.220.469
2r3fSC8Cyclin-dependent kinase 22.7.11.220.466
3r83Z14Cyclin-dependent kinase 22.7.11.220.466
2r3q5SCCyclin-dependent kinase 22.7.11.220.465
1pxoCK7Cyclin-dependent kinase 22.7.11.220.462
4fks46KCyclin-dependent kinase 22.7.11.220.462
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.460
3qzgX67Cyclin-dependent kinase 22.7.11.220.458
3r8uZ31Cyclin-dependent kinase 22.7.11.220.458
1h0w207Cyclin-dependent kinase 22.7.11.220.457
1ke5LS1Cyclin-dependent kinase 22.7.11.220.457
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.457
3qtsX46Cyclin-dependent kinase 22.7.11.220.457
3r7yZ04Cyclin-dependent kinase 22.7.11.220.456
3r7uX96Cyclin-dependent kinase 22.7.11.220.454
2vtsLZCCyclin-dependent kinase 22.7.11.220.452
1hckATPCyclin-dependent kinase 22.7.11.220.451
3raiX85Cyclin-dependent kinase 22.7.11.220.451
4fkg4CKCyclin-dependent kinase 22.7.11.220.450
3qx2X63Cyclin-dependent kinase 22.7.11.220.449
3rk708ZCyclin-dependent kinase 22.7.11.220.449
2c69CT8Cyclin-dependent kinase 22.7.11.220.448
3lfnA27Cyclin-dependent kinase 22.7.11.220.448
3qxoX65Cyclin-dependent kinase 22.7.11.220.448
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.447
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.447
2vv9IM9Cyclin-dependent kinase 22.7.11.220.447
1pxmCK5Cyclin-dependent kinase 22.7.11.220.446
2a4lRRCCyclin-dependent kinase 22.7.11.220.445
3rk909ZCyclin-dependent kinase 22.7.11.220.445
4fkv61KCyclin-dependent kinase 22.7.11.220.444
2r3p3SCCyclin-dependent kinase 22.7.11.220.443
3sw719KCyclin-dependent kinase 22.7.11.220.443
2uzoC62Cyclin-dependent kinase 22.7.11.220.440