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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xmvADPProtein RecA

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1xmvADPProtein RecA/1.000
1xmsANPProtein RecA/0.588
2zreAGSProtein RecA/0.487
2zroADPProtein RecA/0.473
2zrjAGSProtein RecA/0.471
2zrfDTPProtein RecA/0.468
1xp8AGSProtein RecA/0.459
5dp2NAPCurF/0.459
2zr9DTPProtein RecA/0.445
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444