Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wxjIPLTryptophan synthase alpha chain

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1wxjIPLTryptophan synthase alpha chain/1.000
2xtnGTPGTPase IMAP family member 2/0.533
1s3uTQDDihydrofolate reductase1.5.1.30.513
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.509
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.508
3nmpPYVAbscisic acid receptor PYL2/0.507
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.505
2ldbNADL-lactate dehydrogenase1.1.1.270.504
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.503
3fp0FP015-O-acetyltransferase/0.503
1drhNAPDihydrofolate reductase1.5.1.30.502
1x1cSAHC-20 methyltransferase/0.502
3a0tADPSensor histidine kinase/0.502
1xe65FPPlasmepsin-23.4.23.390.500
2rh9IGPTryptophan synthase alpha chain/0.500
4fcr0TMHeat shock protein HSP 90-alpha/0.500
2a9y26AAdenosine kinase2.7.1.200.499
2rqfJH3Hemolymph juvenile hormone binding protein/0.498
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.498
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.498
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.497
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.496
3v2uATPProtein GAL3/0.496
1a5bIGPTryptophan synthase alpha chain/0.495
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.495
2gjlFMNNitronate monooxygenase1.13.12.160.494
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.494
4a802ANMajor pollen allergen Bet v 1-A/0.494
4h3j10WBeta-secretase 13.4.23.460.494
1mvsDTMDihydrofolate reductase1.5.1.30.493
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.493
4opiFDAConserved Archaeal protein/0.493
1rx1NAPDihydrofolate reductase1.5.1.30.492
1xddAAYIntegrin alpha-L/0.492
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.492
2xabVHDHeat shock protein HSP 90-alpha/0.492
1culFOKAdenylate cyclase type 2/0.491
1culFOKAdenylate cyclase type 5/0.491
1kvkATPMevalonate kinase2.7.1.360.491
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.491
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.491
2rlcCHDCholoylglycine hydrolase3.5.1.240.490
3gwdNAPCyclohexanone monooxygenase/0.490
3h3qH13Collagen type IV alpha-3-binding protein/0.490
1o9bNAIQuinate/shikimate dehydrogenase/0.489
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.488
1tl7FOKAdenylate cyclase type 2/0.488
1tl7FOKAdenylate cyclase type 5/0.488
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.488
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.488
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.487
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.486
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.486
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.486
1cjkFOKAdenylate cyclase type 2/0.485
1cjkFOKAdenylate cyclase type 5/0.485
2i7pACOPantothenate kinase 32.7.1.330.485
2xlrFADPutative flavin-containing monooxygenase/0.485
2c29NAPDihydroflavonol 4-reductase/0.484
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.484
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.484
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.484
4rvdSAMD-mycarose 3-C-methyltransferase/0.483
2ab8MTPAdenosine kinase2.7.1.200.482
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.482
4dieC5PCytidylate kinase/0.482
4eki0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.482
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.481
1k8y13PTryptophan synthase alpha chain/0.481
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.481
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.481
4dbzNDPPutative ketoacyl reductase1.3.10.481
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.480
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.480
3ekuCY9Actin-5C/0.480
3h3sH15Collagen type IV alpha-3-binding protein/0.480
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.480
4q71FADBifunctional protein PutA/0.480
4u7wNDPMxaA/0.480
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.479
2vbdV10Isopenicillin N synthase1.21.3.10.479
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.479
4m4922YL-lactate dehydrogenase A chain1.1.1.270.479
2ftoTMPThymidylate synthase/0.478
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.478
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.478
1ay0TPPTransketolase 12.2.1.10.477
1c1dNAIPhenylalanine dehydrogenase/0.477
2fj1CTCTetracycline repressor protein class D/0.477
3gxfIFMGlucosylceramidase3.2.1.450.477
3lqfNADGalactitol dehydrogenase/0.477
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.477
1gj5130Prothrombin3.4.21.50.476
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.476
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.476
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.476
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
1dliUDXUDP-glucose 6-dehydrogenase/0.475
1kh3ANPArgininosuccinate synthase/0.475
1w6jR71Lanosterol synthase5.4.99.70.475
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.475
2rhgIGPTryptophan synthase alpha chain/0.475
2x06NADL-sulfolactate dehydrogenase/0.475
4iarERM5-hydroxytryptamine receptor 1B/0.475
4r1lADPPhenylacetate-coenzyme A ligase/0.475
1u2yGOXPancreatic alpha-amylase/0.474
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.474
2a5kAZPReplicase polyprotein 1ab3.4.220.474
2gjnFMNNitronate monooxygenase1.13.12.160.474
2gv8NDPThiol-specific monooxygenase1.14.130.474
3qt62P0Mevalonate diphosphate decarboxylase/0.474
4fxy0W2Neurolysin, mitochondrial3.4.24.160.474
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.474
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.474
1dhfFOLDihydrofolate reductase1.5.1.30.473
1o2g696Prothrombin3.4.21.50.473
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.473
1umaIN2Prothrombin3.4.21.50.473
3h3t16HCollagen type IV alpha-3-binding protein/0.473
3own3OWRenin3.4.23.150.473
4dc0NDPPutative ketoacyl reductase1.3.10.473
1beuIPLTryptophan synthase alpha chain/0.472
1kquBR4Phospholipase A2, membrane associated/0.472
1me6IVSPlasmepsin-23.4.23.390.472
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.472
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.472
2vcmM11Isopenicillin N synthase1.21.3.10.472
2y6fM9FIsopenicillin N synthase1.21.3.10.472
3fun798Leukotriene A-4 hydrolase3.3.2.60.472
3ixp834Ecdysone receptor/0.472
3oibFDAPutative acyl-CoA dehydrogenase/0.472
4a6rTA8Probable aminotransferase/0.472
4a83DXCMajor pollen allergen Bet v 1-A/0.472
4a862ANMajor pollen allergen Bet v 1-A/0.472
4jicFMNGTN Reductase/0.472
4m9aFDAAcyl-CoA dehydrogenase/0.472
1dyjDDFDihydrofolate reductase1.5.1.30.471
1ia3TQ5Dihydrofolate reductase1.5.1.30.471
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
3fpzAHZThiamine thiazole synthase/0.471
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.471
4friDWABeta-secretase 13.4.23.460.471
4g95OAGDihydrofolate reductase1.5.1.30.471
1m78NDPDihydrofolate reductase1.5.1.30.470
1rszDIHPurine nucleoside phosphorylase2.4.2.10.470
3ai3NDPNADPH-sorbose reductase/0.470
3c15FOKAdenylate cyclase type 2/0.470
3c15FOKAdenylate cyclase type 5/0.470
4bb3KKAIsopenicillin N synthase1.21.3.10.470
4fweFADLysine-specific histone demethylase 1B10.470
1g1aNADdTDP-glucose 4,6-dehydratase/0.469
1kkq471Peroxisome proliferator-activated receptor alpha/0.469
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.469
1obnASVIsopenicillin N synthase1.21.3.10.469
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
2qg0A94Heat shock protein HSP 90-alpha/0.469
3f03FMNPentaerythritol tetranitrate reductase/0.469
3ful52DLeukotriene A-4 hydrolase3.3.2.60.469
3h3r14HCollagen type IV alpha-3-binding protein/0.469
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.469
4df2FMNNADPH dehydrogenase/0.469
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.469
4m0cFMNFMN-dependent NADH-azoreductase 1/0.469
4q72FADBifunctional protein PutA/0.469
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.469
1ia4TQ6Dihydrofolate reductase1.5.1.30.468
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.468
2il2LIXRenin3.4.23.150.468
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3fsjD7KBenzoylformate decarboxylase4.1.1.70.468
3in6FMNUncharacterized protein/0.468
3q43D66M1 family aminopeptidase3.4.110.468
3rq8AP5ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.468
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4k6fNAPPutative Acetoacetyl-CoA reductase/0.468
4kbyC2EStimulator of interferon genes protein/0.468
1gpeFADGlucose oxidase1.1.3.40.467
1s3vTQDDihydrofolate reductase1.5.1.30.467
2bxmIMNSerum albumin/0.467
2c20NADUDP-glucose 4-epimerase/0.467
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.467
2vprTDCTetracycline repressor protein class H/0.467
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.467
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.467
3e8xNAPBH1520 protein/0.467
3fr5I4AFatty acid-binding protein, adipocyte/0.467
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.467
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.467
3ou2SAHSAM-dependent methyltransferase/0.467
4dpy2P0Mevalonate diphosphate decarboxylase/0.467
4ead0NPThymidine phosphorylase2.4.2.40.467
1h74ADPHomoserine kinase2.7.1.390.466
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1lf2R37Plasmepsin-23.4.23.390.466
1qiqACCIsopenicillin N synthase1.21.3.10.466
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.466
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.466
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.466
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.466
4h1e10JBeta-secretase 13.4.23.460.466
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.466
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.466
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.466
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.466
4ybrNAPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.466
5czySAMEukaryotic huntingtin interacting protein B/0.466
1rzuADPGlycogen synthase 12.4.1.210.465
1txtCAAHMG-CoA synthase/0.465
1tysTMPThymidylate synthase/0.465
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.465
2bxqIMNSerum albumin/0.465
2c27ACOMycothiol acetyltransferase2.3.1.1890.465
2g1n1IGRenin3.4.23.150.465
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.465
3atyFMNProstaglandin F2a synthase/0.465
3oafOAGDihydrofolate reductase1.5.1.30.465
3s3vTOPDihydrofolate reductase1.5.1.30.465
4an4DUDPutative glycosyl transferase/0.465
4j0v1H7Beta-secretase 13.4.23.460.465
4mkhAP5Adenylate kinase/0.465
4qaiFMNNADPH dehydrogenase/0.465
1dyhDZFDihydrofolate reductase1.5.1.30.464
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.464
1h50FMNPentaerythritol tetranitrate reductase/0.464
1hb3SCVIsopenicillin N synthase1.21.3.10.464
1pqc444Oxysterols receptor LXR-beta/0.464
1u0hFOKAdenylate cyclase type 2/0.464
1u0hFOKAdenylate cyclase type 5/0.464
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.464
2dsgSAHDiphthine synthase/0.464
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.464
2fonFADAcyl-coenzyme A oxidase/0.464
2gvdFKPAdenylate cyclase type 2/0.464
2gvdFKPAdenylate cyclase type 5/0.464
2vkeTACTetracycline repressor protein class D/0.464
2xviFADPutative flavin-containing monooxygenase/0.464
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.464
3c16FOKAdenylate cyclase type 2/0.464
3c16FOKAdenylate cyclase type 5/0.464
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.464
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.464
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.464
3uylTYDProbable NDP-rhamnosyltransferase/0.464
3zkyWT4Isopenicillin N synthase1.21.3.10.464
4b0qGMFBeta-secretase 13.4.23.460.464
4dfrMTXDihydrofolate reductase1.5.1.30.464
4h3f10OBeta-secretase 13.4.23.460.464
4lxa1YSBeta-secretase 13.4.23.460.464
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.464
5stdUNNScytalone dehydratase4.2.1.940.464
1dljUGAUDP-glucose 6-dehydrogenase/0.463
1dr2TAPDihydrofolate reductase1.5.1.30.463
1dr3HBIDihydrofolate reductase1.5.1.30.463
1jolFFODihydrofolate reductase1.5.1.30.463
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.463
1sb1165Prothrombin3.4.21.50.463
2e0nSAHPrecorrin-2 C20-methyltransferase/0.463
2fxuBIDActin, alpha skeletal muscle/0.463
2g8yNADHydroxycarboxylate dehydrogenase B/0.463
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.463
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.463
3bgxMEFThymidylate synthase/0.463
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.463
3eigMTXDihydrofolate reductase1.5.1.30.463
3h06VBPGlutamate receptor 2/0.463
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.463
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.463
4du82P0Mevalonate diphosphate decarboxylase/0.463
4i0j842Beta-secretase 13.4.23.460.463
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.463
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
1b2lNDCAlcohol dehydrogenase1.1.1.10.462
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.462
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.462
3phiNDPShikimate dehydrogenase (NADP(+))/0.462
3zksWZVBeta-secretase 23.4.23.450.462
4b79NADProbable short-chain dehydrogenase/0.462
4j7gTRHPCZA361.3/0.462
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.461
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.461
1guyNADMalate dehydrogenase/0.461
1uxjNADMalate dehydrogenase/0.461
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.461
2dhfDZFDihydrofolate reductase1.5.1.30.461
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.461
2zcvNDPQuinone oxidoreductase 21.6.5.20.461
3gqvNAPEnoyl reductase LovC10.461
3gviADPMalate dehydrogenase/0.461
4h3g10QBeta-secretase 13.4.23.460.461
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.461
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.460
1h73ANPHomoserine kinase2.7.1.390.460
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.460
1oc1ASVIsopenicillin N synthase1.21.3.10.460
1pq944BOxysterols receptor LXR-beta/0.460
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.460
1v35NAIEnoyl-ACP reductase/0.460
2ea2F77Methionine aminopeptidase 2/0.460
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.460
2givACOHistone acetyltransferase KAT8/0.460
2y4gTIRTamL/0.460
2zseACPPantothenate kinase2.7.1.330.460
3qvrFADGlucose oxidase1.1.3.40.460
4afgQMRAchbp/0.460
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.460
4cdmFO1Deoxyribodipyrimidine photolyase/0.460
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.460
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.460
4opgFDAConserved Archaeal protein/0.460
1a9cGTPGTP cyclohydrolase 13.5.4.160.459
1dr5NAPDihydrofolate reductase1.5.1.30.459
1e2nRCAThymidine kinase/0.459
1hb1OCVIsopenicillin N synthase1.21.3.10.459
1hfqMOTDihydrofolate reductase1.5.1.30.459
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.459
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
2gesCOKPantothenate kinase2.7.1.330.459
2iviACWIsopenicillin N synthase1.21.3.10.459
2ohjFMNType A flavoprotein FprA10.459
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.459
2rhrEMOPutative ketoacyl reductase1.3.10.459
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.459
3up0D7SaceDAF-12/0.459
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.459
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.459
4fhd0TTSpore photoproduct lyase/0.459
4q73FADBifunctional protein PutA/0.459
1dhjMTXDihydrofolate reductase1.5.1.30.458
1p0pBCHCholinesterase3.1.1.80.458
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
1vbiNADMalate/L-lactate dehydrogenase family protein/0.458
2aa3AP0L-lactate dehydrogenase/0.458
2cv2GSUGlutamate--tRNA ligase6.1.1.170.458
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.458
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
2fznFADBifunctional protein PutA1.5.5.20.458
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.458
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.458
3aezGDPPantothenate kinase2.7.1.330.458
3atzFMNProstaglandin F2a synthase/0.458
3b28B2XHeat shock protein HSP 90-alpha/0.458
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3fhxPLPPyridoxal kinase2.7.1.350.458
3fr4F8AFatty acid-binding protein, adipocyte/0.458
3otwCOAPhosphopantetheine adenylyltransferase/0.458
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.458
4a8v2ANMajor pollen allergen Bet v 1-J/0.458
4fm80UQBeta-secretase 13.4.23.460.458
4lrrCF9Thymidylate synthase/0.458
4oqyNDP(S)-imine reductase/0.458
4r81FMNPredicted NADH dehydrogenase/0.458
4rp8ASCAscorbate-specific PTS system EIIC component/0.458
1bil0IURenin3.4.23.150.457
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1d6w00RProthrombin3.4.21.50.457
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.457
1pd9CO4Dihydrofolate reductase1.5.1.30.457
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.457
1qy5NECEndoplasmin/0.457
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.457
2bjfDXCCholoylglycine hydrolase3.5.1.240.457
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.457
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.457
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.457
2pcmSAHDiphthine synthase/0.457
2zjmF1MBeta-secretase 13.4.23.460.457
3ensENSCoagulation factor X3.4.21.60.457
3i0pNADMalate dehydrogenase, putative/0.457
3ibqATPPyridoxal kinase/0.457
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
3r4pFU7Heat shock protein HSP 90-alpha/0.457
3tlc7MDMicrocin C7 self-immunity protein MccF/0.457
4c77N01Phenylacetone monooxygenase1.14.13.920.457
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
4dptAGSMevalonate diphosphate decarboxylase/0.457
4twnB96Ephrin type-A receptor 32.7.10.10.457
1bk0ACVIsopenicillin N synthase1.21.3.10.456
1dgmADNAdenosine kinase2.7.1.200.456
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.456
1pl6572Sorbitol dehydrogenase1.1.1.140.456
1ra8FOLDihydrofolate reductase1.5.1.30.456
1rneC60Renin3.4.23.150.456
1tqf32PBeta-secretase 13.4.23.460.456
1trgCB3Thymidylate synthase/0.456
1udaUFGUDP-glucose 4-epimerase5.1.3.20.456
2e8qSAHDiphthine synthase/0.456
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
3c3dFO12-phospho-L-lactate transferase/0.456
3drcMTXDihydrofolate reductase1.5.1.30.456
3gvhNADMalate dehydrogenase/0.456
3o6o94MHeat shock protein 83/0.456
3p0hFSEPutative tyrosyl-tRNA synthetase/0.456
3tneRITCandidapepsin-13.4.23.240.456
4ambDUDPutative glycosyl transferase/0.456
4iraFAD4-hydroxyphenylacetate 3-monooxygenase/0.456
1cs4FOKAdenylate cyclase type 2/0.455
1cs4FOKAdenylate cyclase type 5/0.455
1draMTXDihydrofolate reductase1.5.1.30.455
1eioGCHGastrotropin/0.455
1i59ANPChemotaxis protein CheA2.7.13.30.455
1ia1NDPDihydrofolate reductase1.5.1.30.455
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1qy8RDIEndoplasmin/0.455
1rb3MTXDihydrofolate reductase1.5.1.30.455
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.455
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2lfoGCHFatty acid-binding protein, liver/0.455
2xhrC0PHeat shock protein HSP 90-alpha/0.455
3b9lAZZSerum albumin/0.455
3e92G6AMitogen-activated protein kinase 14/0.455
3ogwIMNLactoperoxidase1.11.1.70.455
3s1dZIRCytokinin dehydrogenase 11.5.99.120.455
3t4eNADQuinate/shikimate dehydrogenase/0.455
3vp6HLDGlutamate decarboxylase 14.1.1.150.455
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.455
4m6jNDPDihydrofolate reductase1.5.1.30.455
5a9sNAPPutative dehydrogenase/0.455
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.455
1dr3TAPDihydrofolate reductase1.5.1.30.454
1gj4132Prothrombin3.4.21.50.454
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.454
1szgFNSCytochrome b2, mitochondrial1.1.2.30.454
1u0yPA7Endoplasmin/0.454
1w6hTITPlasmepsin-23.4.23.390.454
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.454
1yzqGNPRas-related protein Rab-6A/0.454
2pb6SAHDiphthine synthase/0.454
2w6qOA5Biotin carboxylase6.3.4.140.454
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.454
2zvbSAHPrecorrin-3 C17-methyltransferase/0.454
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3k5c0BIBeta-secretase 13.4.23.460.454
3mdmFJZCholesterol 24-hydroxylase/0.454
3vhaVHAHeat shock protein HSP 90-alpha/0.454
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.454
4djy0KRBeta-secretase 13.4.23.460.454
4ekg0QJHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.454
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.454
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4jlm1NNDeoxycytidine kinase2.7.1.740.454
4k28NADShikimate dehydrogenase family protein/0.454
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.454
1fwkADPHomoserine kinase2.7.1.390.453
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.453
1iy8NADLevodione reductase/0.453
1nvtNAPShikimate dehydrogenase (NADP(+))/0.453
1vf3GDNGlutathione S-transferase 32.5.1.180.453
2fk8SAMHydroxymycolate synthase MmaA42.1.10.453
3c35KAIGlutamate receptor ionotropic, kainate 1/0.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3ndjJHZMethyltransferase/0.453
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.453
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.453
4bfzZVZPantothenate kinase2.7.1.330.453
4dk70KSOxysterols receptor LXR-beta/0.453
4p9dTMPDeoxycytidylate deaminase/0.453
4yqfGDPSeptin-9/0.453
8dfrNDPDihydrofolate reductase1.5.1.30.453
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.452
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.452
1cjuFOKAdenylate cyclase type 2/0.452
1cjuFOKAdenylate cyclase type 5/0.452
1dyiFOLDihydrofolate reductase1.5.1.30.452
1ex75GPGuanylate kinase2.7.4.80.452
1h51FMNPentaerythritol tetranitrate reductase/0.452
1j9zFADNADPH--cytochrome P450 reductase/0.452
1mvtDTMDihydrofolate reductase1.5.1.30.452
1zgbA1EAcetylcholinesterase3.1.1.70.452
2ejvNADL-threonine 3-dehydrogenase/0.452
2ejzSAHDiphthine synthase/0.452
2emuSAHDiphthine synthase/0.452
2fypRDEEndoplasmin/0.452
2hfuMEVMevalonate kinase/0.452
2hu2NADC-terminal binding protein 1/0.452
2qo9ANPEphrin type-A receptor 32.7.10.10.452
2vbpVB1Isopenicillin N synthase1.21.3.10.452
2vq7NAPPutative flavin-containing monooxygenase/0.452
2zsaADPPantothenate kinase2.7.1.330.452
3akn11DFatty acid-binding protein, intestinal/0.452
3b2sB2STrichothecene 3-O-acetyltransferase/0.452
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3mauEXTPutative sphingosine-1-phosphate lyase/0.452
3udn09BBeta-secretase 13.4.23.460.452
3whaWHAHeat shock protein HSP 90-alpha/0.452
3zidGDPTubulin-like protein CetZ/0.452
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.452
4kgkGTPUncharacterized protein/0.452
4kp5E1FCarbonic anhydrase 124.2.1.10.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4o1mNADEnoyl-acyl carrier reductase/0.452
4pnmNU1Tankyrase-22.4.2.300.452
4q0kGA3Phytohormone-binding protein/0.452
4rsyB3NLeukotriene A-4 hydrolase3.3.2.60.452
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.451
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.451
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.451
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.451
1szfFMNCytochrome b2, mitochondrial1.1.2.30.451
1tj0FADBifunctional protein PutA1.5.5.20.451
1u71MXADihydrofolate reductase1.5.1.30.451
1ur5NADMalate dehydrogenase/0.451
1uyhPU0Heat shock protein HSP 90-alpha/0.451
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2a94AP0L-lactate dehydrogenase1.1.1.270.451
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.451
2eleSAHDiphthine synthase/0.451
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.451
2g1r3IGRenin3.4.23.150.451
2j3qTFLAcetylcholinesterase3.1.1.70.451
2jb4A14Isopenicillin N synthase1.21.3.10.451
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.451
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.451
3eksCY9Actin-5C/0.451
3fr28CAFatty acid-binding protein, adipocyte/0.451
3ipkPMSSurface protein adhesin/0.451
3rdqDTBStreptavidin/0.451
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.451
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.451
4ocvANPAminoglycoside phosphotransferase/0.451
4z26FADPutative GMC-type oxidoreductase R13510.451
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.451
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.450
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.450
1cjvDADAdenylate cyclase type 2/0.450
1cjvDADAdenylate cyclase type 5/0.450
1e1kFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.450
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.450
1icqOPD12-oxophytodienoate reductase 11.3.1.420.450
1jpaANPEphrin type-B receptor 22.7.10.10.450
1mjbACOHistone acetyltransferase ESA1/0.450
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.450
1t7o152Carnitine O-acetyltransferase2.3.1.70.450
2dvlFADAcyl-CoA dehydrogenase/0.450
2e20B4PPropionate kinase/0.450
2g1y5IGRenin3.4.23.150.450
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.450
2qrqS13Glycogen phosphorylase, muscle form2.4.1.10.450
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.450
2w3wVG9Dihydrofolate reductase/0.450
2wi72KLHeat shock protein HSP 90-alpha/0.450
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.450
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.450
3iocA5DPantothenate synthetase6.3.2.10.450
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.450
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.450
4a87NARMajor pollen allergen Bet v 1-A/0.450
4jqlVJ6Heat shock protein HSP 90-alpha/0.450
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.450
5a1tNAIL-lactate dehydrogenase/0.450
5dp2NAPCurF/0.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.449
1t2cNAIL-lactate dehydrogenase1.1.1.270.449
1xe55FEPlasmepsin-23.4.23.390.449
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.449
2bufADPAcetylglutamate kinase/0.449
2e1zB4PPropionate kinase/0.449
2e8hSAHDiphthine synthase/0.449
2emrSAHDiphthine synthase/0.449
2gywOBIAcetylcholinesterase3.1.1.70.449
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.449
2v16C47Renin3.4.23.150.449
2vttLZDCyclin-dependent kinase 22.7.11.220.449
2zsbADPPantothenate kinase2.7.1.330.449
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.449
3bv2P38Mitogen-activated protein kinase 14/0.449
3ed1GA3Gibberellin receptor GID1/0.449
3h2sNDPPutative NADH-flavin reductase/0.449
3hl0NADMaleylacetate reductase/0.449
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3zoiM2WIsopenicillin N synthase1.21.3.10.449
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.449
4e32DWNMethyltransferase/0.449
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.449
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.449
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.449
4j491J1Uncharacterized protein/0.449
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.449
4jtqNAPAldo-keto reductase family 1 member C2/0.449
4tm4FDAKtzI/0.449
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.449
1a72PADAlcohol dehydrogenase E chain1.1.1.10.448
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.448
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.448
1npdNADQuinate/shikimate dehydrogenase/0.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1qoqIGPTryptophan synthase alpha chain/0.448
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.448
1upw444Oxysterols receptor LXR-beta/0.448
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1zgv501Prothrombin3.4.21.50.448
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.448
2ag1TPPBenzaldehyde lyase/0.448
2bbwGP5Adenylate kinase 4, mitochondrial/0.448
2daaDCSD-alanine aminotransferase2.6.1.210.448
2ozuACOHistone acetyltransferase KAT6A/0.448
2rc4ACOHistone acetyltransferase KAT6A/0.448
2yegXQGHeat shock protein HSP 90-alpha/0.448
2zgb21UProthrombin3.4.21.50.448
3c36KAIGlutamate receptor ionotropic, kainate 1/0.448
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3fu5492Leukotriene A-4 hydrolase3.3.2.60.448
3gegNADShort-chain dehydrogenase/reductase SDR/0.448
3k8q22APurine nucleoside phosphorylase2.4.2.10.448
3p62FMNPentaerythritol tetranitrate reductase/0.448
3r4nFU5Heat shock protein HSP 90-alpha/0.448
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.448
3vydVYDRenin3.4.23.150.448
3wagTYDGlycosyltransferase/0.448
4b1rITCTetracycline repressor protein class D/0.448
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.448
4ke11R6Beta-secretase 13.4.23.460.448
4uugPXGBranched-chain amino acid aminotransferase, putative/0.448
4ycpFMNtRNA-dihydrouridine(16) synthase/0.448
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
4zwpM44Xaa-Pro dipeptidase3.4.13.90.448
1cjtFOKAdenylate cyclase type 2/0.447
1cjtFOKAdenylate cyclase type 5/0.447
1diuBDMDihydrofolate reductase1.5.1.30.447
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1jwtBLIProthrombin3.4.21.50.447
1kfcIPLTryptophan synthase alpha chain/0.447
1kp2ATPArgininosuccinate synthase6.3.4.50.447
1lkeDOGBilin-binding protein/0.447
1mjaCOAHistone acetyltransferase ESA1/0.447
1p0hACOMycothiol acetyltransferase2.3.1.1890.447
1psa0ZLPepsin A3.4.23.10.447
1qo8FADFumarate reductase flavoprotein subunit/0.447
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
1u65CP0Acetylcholinesterase3.1.1.70.447
1x1bSAHC-20 methyltransferase/0.447
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.447
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.447
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.447
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2cig1DGDihydrofolate reductase1.5.1.30.447
2d81RB3Poly(3-hydroxybutyrate) depolymerase/0.447
2f3mGTDGlutathione S-transferase Mu 12.5.1.180.447
2fhnBNIAvidin-related protein 4/5/0.447
2g1s4IGRenin3.4.23.150.447
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.447
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.447
2he5NDPAldo-keto reductase family 1 member C211.1.10.447
2hg1N5OEndoplasmin/0.447
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.447
2ou2ACOHistone acetyltransferase KAT5/0.447
2pciSAHDiphthine synthase/0.447
2q46NAPUncharacterized protein At5g02240/0.447
2r8pT6FTransketolase 1/0.447
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.447
2wo7ASVIsopenicillin N synthase1.21.3.10.447
2zff53UProthrombin3.4.21.50.447
3clsFADElectron transfer flavoprotein subunit alpha/0.447
3cluFADElectron transfer flavoprotein subunit alpha/0.447
3csoXNIGenome polyprotein2.7.7.480.447
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.447
3gwfNAPCyclohexanone monooxygenase/0.447
3jpuTY4Transcriptional activator protein LasR/0.447
3khuUPGUDP-glucose 6-dehydrogenase1.1.1.220.447
3l5dBDVBeta-secretase 13.4.23.460.447
3q7dNPXProstaglandin G/H synthase 21.14.99.10.447
3rpeFADPutative modulator of drug activity/0.447
3tjzGNPADP-ribosylation factor 1/0.447
3tydXHPDihydropteroate synthase/0.447
3tyeXTZDihydropteroate synthase/0.447
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.447
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.447
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.447
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.447
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.447
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.447
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.447
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.447
5jy1NADPutative short-chain dehydrogenase/reductase/0.447
3vw7VPXProteinase-activated receptor 1/0.447
1bim0QBRenin3.4.23.150.446
1blzACVIsopenicillin N synthase1.21.3.10.446
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.446
1kfbIGPTryptophan synthase alpha chain/0.446
1qjfACSIsopenicillin N synthase1.21.3.10.446
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.446
1x1aSAMC-20 methyltransferase/0.446
1zrzBI1Protein kinase C iota type2.7.11.130.446
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.446
2drcMTXDihydrofolate reductase1.5.1.30.446
2hr8SAHDiphthine synthase/0.446
2iyfERYOleandomycin glycosyltransferase2.4.10.446
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.446
2q9fC3SCholesterol 24-hydroxylase/0.446
2v3hI25Prothrombin3.4.21.50.446
2v7qATPATP synthase subunit alpha, mitochondrial/0.446
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.446
2xveFADPutative flavin-containing monooxygenase/0.446
2zsiGA4Gibberellin receptor GID1A30.446
3c3xNAPEugenol synthase 11.1.1.3180.446
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.446
3co93MSGenome polyprotein2.7.7.480.446
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3gfbNADL-threonine 3-dehydrogenase/0.446
3maaFKPAdenylate cyclase type 2/0.446
3maaFKPAdenylate cyclase type 5/0.446
3vdqNAD3-hydroxybutyrate dehydrogenase/0.446
3vswR31Renin3.4.23.150.446
4e2bFMNDehydrogenase/0.446
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.446
4g3jVNTLanosterol 14-alpha-demethylase/0.446
4kp8E1GCarbonic anhydrase 124.2.1.10.446
4m83ERYOleandomycin glycosyltransferase2.4.10.446
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.446
5a3bAPRSIR2 family protein/0.446
4xnw2IDP2Y purinoceptor 1/0.446
4z36ON3Lysophosphatidic acid receptor 1/0.446
1cjvFOKAdenylate cyclase type 2/0.445
1cjvFOKAdenylate cyclase type 5/0.445
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.445
1f5fDHTSex hormone-binding globulin/0.445
1hdoNAPFlavin reductase (NADPH)/0.445
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.445
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.445
1kwqSG1Carbonic anhydrase 24.2.1.10.445
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.445
1omoNADAlanine dehydrogenase/0.445
1rd4L08Integrin alpha-L/0.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
2dteNAIGlucose 1-dehydrogenase related protein/0.445
2eh5SAHDiphthine synthase/0.445
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.445
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.445
2pg0FADAcyl-CoA dehydrogenase/0.445
2w6pOA4Biotin carboxylase6.3.4.140.445
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.445
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3isiB88Putative dipeptidase/0.445
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.445
3mk6ACOPantothenate kinase 32.7.1.330.445
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.445
4a86H35Major pollen allergen Bet v 1-A/0.445
4djw0KPBeta-secretase 13.4.23.460.445
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.445
4i1iNADMalate dehydrogenase/0.445
4lcjNADC-terminal-binding protein 2/0.445
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.445
4v2gITCTetracycline repressor protein class D/0.445
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.445
1bcuPRLProthrombin3.4.21.50.444
1ddrMTXDihydrofolate reductase1.5.1.30.444
1dhiMTXDihydrofolate reductase1.5.1.30.444
1fy7COAHistone acetyltransferase ESA1/0.444
1goxFMNPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.444
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.444
1ivsVAAValine--tRNA ligase6.1.1.90.444
1rkwPNTHTH-type transcriptional regulator QacR/0.444
1u4oNDDL-lactate dehydrogenase1.1.1.270.444
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.444
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.444
2dv3SAHDiphthine synthase/0.444
2dv7SAHDiphthine synthase/0.444
2e1mFADL-glutamate oxidase/0.444
2fs4PZ1Renin3.4.23.150.444
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.444
2gfdRDAEndoplasmin/0.444
2k62ITLFatty acid-binding protein, liver/0.444
2npxNADNADH peroxidase1.11.1.10.444
2uxoTACHTH-type transcriptional regulator TtgR/0.444
2vyqFADFerredoxin--NADP reductase1.18.1.20.444
2w6zL21Biotin carboxylase6.3.4.140.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3f7bAG5Carbonic anhydrase 44.2.1.10.444
3lpfZ77Beta-glucuronidase3.2.1.310.444
3lsiFADPyranose 2-oxidase/0.444
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.444
3wqmB29Diterpene synthase3.1.7.80.444
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4bfxZVXPantothenate kinase2.7.1.330.444
4blrUTPNTPase P4/0.444
4eqwFADCoenzyme A disulfide reductase/0.444
4fqsLYAThymidylate synthase ThyA/0.444
4k9oTPPBenzoylformate decarboxylase4.1.1.70.444
4oztP1AEcdysone receptor, putative/0.444
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
4z24FADPutative GMC-type oxidoreductase R13510.444
4u140HKMuscarinic acetylcholine receptor M3/0.444
1i6kTYMTryptophan--tRNA ligase6.1.1.20.443
1j0d5PA1-aminocyclopropane-1-carboxylate deaminase3.5.99.70.443
1j21ATPArgininosuccinate synthase/0.443
1qrpHH0Pepsin A-43.4.23.10.443
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.560.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2bvs2CEProthrombin3.4.21.50.443
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.443
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.443
2o12FMNChorismate synthase/0.443
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.443
2tctCTCTetracycline repressor protein class D/0.443
2x0iNAIMalate dehydrogenase/0.443
2x93X93Angiotensin-converting enzyme3.4.15.10.443
2y60M8FIsopenicillin N synthase1.21.3.10.443
2ylrNAPPhenylacetone monooxygenase1.14.13.920.443
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
2zgx29UProthrombin3.4.21.50.443
3d91REMRenin3.4.23.150.443
3juqAJDPhenazine biosynthesis protein A/B/0.443
3lxeTORCarbonic anhydrase 14.2.1.10.443
3ohf3HFBeta-secretase 13.4.23.460.443
3p5pA3CTaxadiene synthase4.2.3.170.443
3r9fGSUMccE protein/0.443
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.443
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4bfvZVVPantothenate kinase2.7.1.330.443
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.443
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.443
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.443
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.443
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.443
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.443
4mv8ACPBiotin carboxylase6.3.4.140.443
4opuFDAConserved Archaeal protein/0.443
4psbGA3Cytokinin-specific binding protein/0.443
4rvnCOAPhenylacetate-coenzyme A ligase/0.443
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.443
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.443
5efwFMNNPH1-1/0.443
5fwnNAPPutative dehydrogenase/0.443
1eveE20Acetylcholinesterase3.1.1.70.442
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1h22E10Acetylcholinesterase3.1.1.70.442
1kvrNADUDP-glucose 4-epimerase5.1.3.20.442
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
1pq6965Oxysterols receptor LXR-beta/0.442
1tllFMNNitric oxide synthase, brain1.14.13.390.442
1tysDHFThymidylate synthase/0.442
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1yc14BCHeat shock protein HSP 90-alpha/0.442
2c12FADNitroalkane oxidase1.7.3.10.442
2clfF6FTryptophan synthase alpha chain/0.442
2cvwGDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
2huxSAHDiphthine synthase/0.442
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.442
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.442
2v95HCYCorticosteroid-binding globulin/0.442
2whqHI6Acetylcholinesterase3.1.1.70.442
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.442
2zf051UProthrombin3.4.21.50.442
3b6zCO7Enoyl reductase LovC10.442
3c1kT15Prothrombin3.4.21.50.442
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3fazNOSPurine nucleoside phosphorylase/0.442
3g6zA7TRenin3.4.23.150.442
3g70A5TRenin3.4.23.150.442
3gonANPPhosphomevalonate kinase/0.442
3ig6438Urokinase-type plasminogen activator3.4.21.730.442
3imgBZ2Pantothenate synthetase6.3.2.10.442
3r96ACOMccE protein/0.442
3r9g7MCMccE protein/0.442
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4ajbTAPIsocitrate dehydrogenase [NADP]1.1.1.420.442
4bixADPSensor histidine kinase CpxA/0.442
4bizADPSensor histidine kinase CpxA/0.442
4f9gC2EStimulator of interferon genes protein/0.442
4g8jTHMUridine phosphorylase/0.442
4h9tHL4Phosphotriesterase/0.442
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.442
4kne1CYDihydrofolate reductase1.5.1.30.442
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.442
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.442
4xgxADPFAD:protein FMN transferase/0.442
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.442
5lc1NADL-threonine 3-dehydrogenase/0.442
1c7oPPGHemolysin/0.441
1gaxVAAValine--tRNA ligase6.1.1.90.441
1icsFMN12-oxophytodienoate reductase 11.3.1.420.441
1jdvADNPurine nucleoside phosphorylase/0.441
1jg0DDTThymidylate synthase/0.441
1mewXMPInosine-5'-monophosphate dehydrogenase/0.441
1q23FUAChloramphenicol acetyltransferase2.3.1.280.441
1rp0AHZThiamine thiazole synthase, chloroplastic/0.441
1t4u81AProthrombin3.4.21.50.441
1tkaN3TTransketolase 12.2.1.10.441
1towCRZFatty acid-binding protein, adipocyte/0.441
1vi2NADQuinate/shikimate dehydrogenase/0.441
1w6rGNTAcetylcholinesterase3.1.1.70.441
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.441
1zxcIH6Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.441
2b53D23Cyclin-dependent kinase 22.7.11.220.441
2e17SAHDiphthine synthase/0.441
2eldSAHDiphthine synthase/0.441
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.441
2g1o2IGRenin3.4.23.150.441
2gdeSN3Prothrombin3.4.21.50.441
2i4qUA4Renin3.4.23.150.441
2ofiADK3-methyladenine DNA glycosylase I/0.441
2xpuTDCTetracycline repressor protein class D/0.441
2zbaZBATrichothecene 3-O-acetyltransferase/0.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3ae4FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.441
3b1dPLSBetaC-S lyase/0.441
3b70NAPEnoyl reductase LovC10.441
3c3eGDP2-phospho-L-lactate transferase/0.441
3hhu819Heat shock protein HSP 90-alpha/0.441
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3lcjCOAPhosphopantetheine adenylyltransferase/0.441
3nsh957Beta-secretase 13.4.23.460.441
3owaFADAcyl-CoA dehydrogenase/0.441
3p82FMNPentaerythritol tetranitrate reductase/0.441
3rqhB6PADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.441
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
4c9oCAMCytochrome P450/0.441
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.441
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.441
4ey6GNTAcetylcholinesterase3.1.1.70.441
4hwkNAPSepiapterin reductase1.1.1.1530.441
4i0i957Beta-secretase 13.4.23.460.441
4i13FOLDihydrofolate reductase1.5.1.30.441
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.441
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.441
4stdBFSScytalone dehydratase4.2.1.940.441
4w5kPLPAspartate aminotransferase, mitochondrial/0.441
4wudANPDNA gyrase subunit B/0.441
4x3mADNRNA 2'-O ribose methyltransferase/0.441
4y35F90Endothiapepsin3.4.23.220.441
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.441
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.440
1ai9NDPDihydrofolate reductase1.5.1.30.440
1fm4DXCMajor pollen allergen Bet v 1-L/0.440
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.440
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.440
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.440
1nytNAPShikimate dehydrogenase (NADP(+))/0.440
1obbNADAlpha-glucosidase3.2.1.200.440
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.440
1tehNADAlcohol dehydrogenase class-31.1.1.10.440
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.440
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2c2aADPSensor histidine kinase/0.440
2ed3SAHDiphthine synthase/0.440
2oapANPType II secretion system protein (GspE-2)/0.440
2ohvNHLGlutamate racemase/0.440
2owgSAHDiphthine synthase/0.440
2p4j23IBeta-secretase 13.4.23.460.440
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.440
2pchSAHDiphthine synthase/0.440
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.440
2xuiTZ5Acetylcholinesterase3.1.1.70.440
2xukTZ5Acetylcholinesterase3.1.1.70.440
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
2zs8ADPPantothenate kinase2.7.1.330.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.440
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.440
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.440
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3g86T18Genome polyprotein2.7.7.480.440
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.440
3lsmSFDPyranose 2-oxidase/0.440
3mpt1GKMitogen-activated protein kinase 14/0.440
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.440
3p8jFMNPentaerythritol tetranitrate reductase/0.440
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.440
3qgi33FGenome polyprotein2.7.7.480.440
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.440
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3tozNADShikimate dehydrogenase (NADP(+))/0.440
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.440
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.440
4du6GTPGTP cyclohydrolase 1/0.440
4ef4C2EStimulator of interferon genes protein/0.440
4jauADPSensor histidine kinase/0.440
4kxjP34Nucleoprotein/0.440
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4locBTNPyruvate carboxylase/0.440
4lol1YEStimulator of interferon genes protein/0.440
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.440
4relKMPGlycosyltransferase/0.440
4tlxFDAKtzI/0.440
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
4udqFAD5-(hydroxymethyl)furfural oxidase/0.440
4wxxSAHDNA (cytosine-5)-methyltransferase 12.1.1.370.440
4x5gFOLDihydrofolate reductase1.5.1.30.440
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.440
5c77SAHProtein arginine N-methyltransferase SFM1/0.440