sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wur | 8DG | GTP cyclohydrolase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1wur | 8DG | GTP cyclohydrolase 1 | / | 1.000 | |
| 1wuq | 8GT | GTP cyclohydrolase 1 | / | 0.559 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.491 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.468 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.459 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.455 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.441 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.441 |