sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wsb | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1wsb | FMN | Flavodoxin | / | 1.000 | |
| 1j8q | FMN | Flavodoxin | / | 0.639 | |
| 2fx2 | FMN | Flavodoxin | / | 0.638 | |
| 1j9g | FMN | Flavodoxin | / | 0.615 | |
| 1azl | FMN | Flavodoxin | / | 0.612 | |
| 1fx1 | FMN | Flavodoxin | / | 0.600 | |
| 1akr | FMN | Flavodoxin | / | 0.595 | |
| 1akw | FMN | Flavodoxin | / | 0.590 | |
| 1c7f | FMN | Flavodoxin | / | 0.574 | |
| 1aku | FMN | Flavodoxin | / | 0.573 | |
| 3f6r | FMN | Flavodoxin | / | 0.570 | |
| 4fx2 | FMN | Flavodoxin | / | 0.569 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.560 | |
| 3kap | FMN | Flavodoxin | / | 0.558 | |
| 5fx2 | FMN | Flavodoxin | / | 0.556 | |
| 1xyv | FMN | Flavodoxin | / | 0.546 | |
| 3kaq | FMN | Flavodoxin | / | 0.545 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.545 | |
| 2fcr | FMN | Flavodoxin | / | 0.534 | |
| 1xyy | FMN | Flavodoxin | / | 0.528 | |
| 1bu5 | RBF | Flavodoxin | / | 0.526 | |
| 3f6s | FMN | Flavodoxin | / | 0.522 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.512 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.509 | |
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 0.509 | |
| 1czn | FMN | Flavodoxin | / | 0.503 | |
| 1ofv | FMN | Flavodoxin | / | 0.494 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.492 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.491 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.490 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.487 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.486 | |
| 4oxx | FMN | Cindoxin | / | 0.486 | |
| 2r8p | T6F | Transketolase 1 | / | 0.485 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.483 | |
| 4h6p | FMN | Chromate reductase | / | 0.483 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.481 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.480 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.476 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.475 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.475 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.474 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.474 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2r8o | T5X | Transketolase 1 | / | 0.474 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.474 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.473 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.473 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.473 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.471 | |
| 4e2d | FMN | Dehydrogenase | / | 0.471 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.471 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.470 | |
| 2r5n | TPP | Transketolase 1 | / | 0.470 | |
| 1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.469 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.469 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.469 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.469 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.467 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.467 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.466 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.466 | |
| 2v5u | FMN | Flavodoxin | / | 0.466 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.465 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.465 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.465 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.465 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
| 1fue | FMN | Flavodoxin | / | 0.464 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.464 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.464 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.464 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.464 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.463 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.463 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 2jgs | BTN | Avidin | / | 0.463 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.463 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.462 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.462 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.462 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.461 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.461 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.460 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.460 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.460 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.460 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.459 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.459 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.458 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.458 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.458 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4j7h | TRH | PCZA361.3 | / | 0.458 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.457 | |
| 3eks | CY9 | Actin-5C | / | 0.457 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.457 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.457 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.457 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.457 | |
| 4d96 | 5PA | D-cysteine desulfhydrase | / | 0.457 | |
| 4e32 | DWN | Methyltransferase | / | 0.457 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.456 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.456 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.456 | |
| 1rxj | BNI | Streptavidin | / | 0.456 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.456 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.456 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.455 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.455 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.455 | |
| 3eku | CY9 | Actin-5C | / | 0.455 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.455 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.455 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.455 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.455 | |
| 4ifb | PPS | Bile salt sulfotransferase | 2.8.2.14 | 0.455 | |
| 4s1h | ADP | Pyridoxal kinase, putative | / | 0.455 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.454 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.454 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.454 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.453 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.453 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.452 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.452 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3ndj | JHZ | Methyltransferase | / | 0.452 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.452 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.451 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.451 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.451 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.451 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.451 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.451 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4iei | ADP | Gene 2 protein | / | 0.451 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.451 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.451 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.451 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2ay5 | IOP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.450 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.450 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.450 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.449 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.449 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.449 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.449 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.448 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.448 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.448 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.448 | |
| 2dsh | SAH | Diphthine synthase | / | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.448 | |
| 3klb | FMN | Uncharacterized protein | / | 0.448 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.448 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.448 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.447 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.447 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.447 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.447 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.447 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.447 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.447 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.447 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.447 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.447 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.446 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.446 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.446 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.446 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.446 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.446 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.445 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.445 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.445 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.445 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.444 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.444 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.444 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.444 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.444 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.444 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3sff | 0DI | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.444 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.444 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.444 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.443 | |
| 3ae4 | N1M | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.443 | |
| 3ae4 | N1M | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.443 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.443 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.443 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.443 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.443 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.443 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.443 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.443 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.442 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.442 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 3q7j | FBO | Tricorn protease-interacting factor F3 | 3.4.11 | 0.442 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.442 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1r2j | FAD | FkbI | / | 0.441 | |
| 2e1z | B4P | Propionate kinase | / | 0.441 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.441 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.441 | |
| 1el4 | CTZ | Obelin | / | 0.440 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.440 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.440 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.440 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2mt9 | FMN | Flavodoxin 2 | / | 0.440 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.440 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.440 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.440 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.440 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.440 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.440 |