Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1woo | THG | Aminomethyltransferase |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1woo | THG | Aminomethyltransferase | / | 1.000 | |
1wop | FFO | Aminomethyltransferase | / | 0.797 | |
2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.523 | |
2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.513 | |
3faz | NOS | Purine nucleoside phosphorylase | / | 0.506 | |
1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.502 | |
5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.499 | |
1lbb | KAI | Glutamate receptor 2 | / | 0.498 | |
1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.496 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.495 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.494 | |
3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.493 | |
2j2p | SC2 | Ficolin-2 | / | 0.491 | |
4twl | ASC | Dioscorin 5 | / | 0.491 | |
2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.487 | |
4g8j | THM | Uridine phosphorylase | / | 0.487 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.486 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.486 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.484 | |
4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.484 | |
4i6g | FAD | Cryptochrome-2 | / | 0.484 | |
3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.483 | |
1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.482 | |
1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.482 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
3ndj | JHZ | Methyltransferase | / | 0.481 | |
2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.480 | |
4kxj | P34 | Nucleoprotein | / | 0.480 | |
2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.479 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.478 | |
2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.478 | |
3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.478 | |
3owx | XRA | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.478 | |
4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.477 | |
3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.477 | |
4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.477 | |
1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.476 | |
2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.476 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.476 | |
2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.475 | |
3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.475 | |
3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.475 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
4ykl | GMP | Aprataxin-like protein | 3 | 0.475 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.475 | |
1t57 | FMN | Conserved protein | / | 0.474 | |
3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.474 | |
4bqy | FNT | Egl nine homolog 1 | / | 0.474 | |
4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.474 | |
1ve3 | SAM | Uncharacterized protein | / | 0.473 | |
4jzr | 4JR | Egl nine homolog 1 | / | 0.473 | |
1e2j | THM | Thymidine kinase | / | 0.472 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
1n2v | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.471 | |
1n5v | NOM | ActVA 6 protein | / | 0.471 | |
1t4u | 81A | Prothrombin | 3.4.21.5 | 0.471 | |
1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.471 | |
4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.471 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.471 | |
2onf | COA | Uncharacterized protein | / | 0.470 | |
2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.470 | |
3i0p | NAD | Malate dehydrogenase, putative | / | 0.470 | |
3vil | SA0 | Beta-glucosidase | / | 0.470 | |
4f3g | KAI | Glutamate receptor 3 | / | 0.470 | |
2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.469 | |
2zhe | 13U | Prothrombin | 3.4.21.5 | 0.469 | |
1bcu | PRL | Prothrombin | 3.4.21.5 | 0.468 | |
2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.468 | |
2xjc | 5GP | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.468 | |
2zgx | 29U | Prothrombin | 3.4.21.5 | 0.468 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.467 | |
2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.467 | |
3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.467 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.467 | |
5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.467 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.466 | |
2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.466 | |
2clf | F6F | Tryptophan synthase alpha chain | / | 0.466 | |
2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.466 | |
3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.466 | |
3gr8 | FMN | NADPH dehydrogenase | / | 0.466 | |
3wqu | ATP | Cell division protein FtsA | / | 0.466 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.466 | |
4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.466 | |
1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.465 | |
2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.465 | |
4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.465 | |
4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
1kzi | THG | Thymidylate synthase | / | 0.464 | |
1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.464 | |
1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.464 | |
2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.464 | |
3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.464 | |
3vt3 | VDX | Vitamin D3 receptor | / | 0.464 | |
4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.463 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.463 | |
1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.463 | |
1xr2 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.463 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.463 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.463 | |
2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.463 | |
3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.463 | |
3klb | FMN | Uncharacterized protein | / | 0.463 | |
3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.463 | |
3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.463 | |
4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.463 | |
1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.462 | |
1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.462 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.462 | |
1txt | CAA | HMG-CoA synthase | / | 0.462 | |
2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.462 | |
3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.462 | |
3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.462 | |
3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.462 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.462 | |
1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.461 | |
2gvd | FKP | Adenylate cyclase type 2 | / | 0.461 | |
2gvd | FKP | Adenylate cyclase type 5 | / | 0.461 | |
2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.461 | |
3c27 | DKK | Prothrombin | 3.4.21.5 | 0.461 | |
3lzz | GDP | Uncharacterized protein | / | 0.461 | |
3p17 | 99P | Prothrombin | 3.4.21.5 | 0.461 | |
3qto | 10P | Prothrombin | 3.4.21.5 | 0.461 | |
4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.461 | |
4n1g | CEI | Obelin | / | 0.461 | |
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.461 | |
1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.460 | |
1xdd | AAY | Integrin alpha-L | / | 0.460 | |
2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.460 | |
2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.460 | |
2zdv | 37U | Prothrombin | 3.4.21.5 | 0.460 | |
3dr7 | GPD | GDP-perosamine synthase | / | 0.460 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.460 | |
5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.460 | |
1o2e | ANN | Phospholipase A2 | 3.1.1.4 | 0.459 | |
1ppj | ANY | Cytochrome b | / | 0.459 | |
1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
2vd4 | P21 | Bifunctional protein GlmU | / | 0.459 | |
3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.459 | |
4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.459 | |
1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.458 | |
1nzq | 162 | Prothrombin | 3.4.21.5 | 0.458 | |
1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
1trg | CB3 | Thymidylate synthase | / | 0.458 | |
2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.458 | |
2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.458 | |
2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.458 | |
3ihz | FK5 | Peptidylprolyl isomerase | / | 0.458 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.458 | |
4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.458 | |
4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.458 | |
5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.458 | |
1mra | APG | Mandelate racemase | / | 0.457 | |
2op1 | 8PC | Enoyl-ACP reductase | / | 0.457 | |
2zhw | 12U | Prothrombin | 3.4.21.5 | 0.457 | |
3fp0 | FP0 | 15-O-acetyltransferase | / | 0.457 | |
3gx9 | TXD | Morphinone reductase | / | 0.457 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.457 | |
5fm7 | ADP | RuvB-like helicase | / | 0.457 | |
1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.456 | |
1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.456 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.456 | |
2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
3e6e | DCS | Alanine racemase | / | 0.456 | |
3own | 3OW | Renin | 3.4.23.15 | 0.456 | |
3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.456 | |
3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.456 | |
1d9i | 00P | Prothrombin | 3.4.21.5 | 0.455 | |
1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.455 | |
3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.455 | |
3lut | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.455 | |
3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
3wqt | ANP | Cell division protein FtsA | / | 0.455 | |
4ai8 | DZA | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.455 | |
4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.455 | |
4mlp | 2CX | Cryptochrome-2 | / | 0.455 | |
1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.454 | |
1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.454 | |
1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.454 | |
1kce | CB3 | Thymidylate synthase | / | 0.454 | |
1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.454 | |
2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.454 | |
3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.454 | |
3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.454 | |
3pl8 | FAD | Pyranose 2-oxidase | / | 0.454 | |
3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.454 | |
1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.453 | |
1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.453 | |
1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
2nm2 | NEU | Dihydroneopterin aldolase | / | 0.453 | |
3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.453 | |
3cnp | SP7 | Polyamine oxidase FMS1 | / | 0.453 | |
3lnm | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.453 | |
3qtv | 06P | Prothrombin | 3.4.21.5 | 0.453 | |
3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.453 | |
4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.453 | |
4e32 | DWN | Methyltransferase | / | 0.453 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.452 | |
1xuz | MMN | Capsule biosynthesis protein | / | 0.452 | |
2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.452 | |
2owf | SAH | Diphthine synthase | / | 0.452 | |
2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.452 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
4g09 | 0VD | Histidinol dehydrogenase | / | 0.452 | |
4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.452 | |
4u8i | FDA | UDP-galactopyranose mutase | / | 0.452 | |
4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.451 | |
1mue | CDD | Prothrombin | 3.4.21.5 | 0.451 | |
1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
1sbz | FMN | Probable UbiX-like flavin prenyltransferase | / | 0.451 | |
2nr4 | FMN | Conserved protein | / | 0.451 | |
2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
3kap | FMN | Flavodoxin | / | 0.451 | |
3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.451 | |
3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.451 | |
4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.451 | |
4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.451 | |
4q72 | FAD | Bifunctional protein PutA | / | 0.451 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.450 | |
1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.450 | |
1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.450 | |
2c3y | HTL | Pyruvate synthase | / | 0.450 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.450 | |
2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
3arq | DM5 | Chitinase A | / | 0.450 | |
3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.450 | |
4gek | GEK | Carboxy-S-adenosyl-L-methionine synthase | / | 0.450 | |
4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.450 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.450 | |
1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.449 | |
1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.449 | |
1lb9 | DNQ | Glutamate receptor 2 | / | 0.449 | |
1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.449 | |
1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.449 | |
1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
2acw | UPG | Glycosyltransferase | / | 0.449 | |
2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
2qzr | S79 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.449 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.449 | |
1a4w | QWE | Prothrombin | 3.4.21.5 | 0.448 | |
1afe | ALZ | Prothrombin | 3.4.21.5 | 0.448 | |
1e2n | RCA | Thymidine kinase | / | 0.448 | |
1ftl | DNQ | Glutamate receptor 2 | / | 0.448 | |
1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.448 | |
1rfu | PLP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.448 | |
2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.448 | |
2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.448 | |
3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.448 | |
3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.448 | |
4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
1ij8 | BNI | Avidin | / | 0.447 | |
1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.447 | |
1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
2c3u | 2TP | Pyruvate synthase | / | 0.447 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.447 | |
3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.447 | |
4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
4isu | IKM | Glutamate receptor 2 | / | 0.447 | |
4y1b | NAP | AntE | / | 0.447 | |
1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.446 | |
1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.446 | |
1o2g | 696 | Prothrombin | 3.4.21.5 | 0.446 | |
1ype | UIP | Prothrombin | 3.4.21.5 | 0.446 | |
1zgi | 382 | Prothrombin | 3.4.21.5 | 0.446 | |
2ejz | SAH | Diphthine synthase | / | 0.446 | |
2gg2 | U12 | Methionine aminopeptidase | / | 0.446 | |
2mok | FMN | Flavodoxin 1 | / | 0.446 | |
2pda | TPP | Pyruvate synthase | / | 0.446 | |
2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
2vz0 | D64 | Pteridine reductase | / | 0.446 | |
2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
2zhq | 27U | Prothrombin | 3.4.21.5 | 0.446 | |
3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.446 | |
4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.446 | |
4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.446 | |
4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.446 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.446 | |
1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
1n5q | TNC | ActVA 6 protein | / | 0.445 | |
1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
1xvv | CCQ | L-carnitine CoA-transferase | / | 0.445 | |
1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.445 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.445 | |
2gg3 | U13 | Methionine aminopeptidase | / | 0.445 | |
2ony | TMJ | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.445 | |
2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.445 | |
2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.445 | |
3arp | DEQ | Chitinase A | / | 0.445 | |
3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.445 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.445 | |
3nf8 | CDQ | Gag-Pol polyprotein | / | 0.445 | |
3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.445 | |
3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.445 | |
4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.445 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.445 | |
4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.445 | |
4p9d | TMP | Deoxycytidylate deaminase | / | 0.445 | |
4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
1cgz | STL | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.444 | |
1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.444 | |
1jwt | BLI | Prothrombin | 3.4.21.5 | 0.444 | |
1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.444 | |
1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
1ols | TDP | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.444 | |
1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.444 | |
1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
1w1v | ALJ | Chitinase | / | 0.444 | |
1ypk | CCR | Prothrombin | 3.4.21.5 | 0.444 | |
2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.444 | |
2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.444 | |
2xgo | ZKD | Uncharacterized protein | / | 0.444 | |
3er9 | 3AT | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.444 | |
3fpk | FAD | Ferredoxin-NADP reductase | / | 0.444 | |
3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.444 | |
3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.444 | |
4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.444 | |
1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.443 | |
1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.443 | |
1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.443 | |
1clq | GDP | DNA-directed DNA polymerase | / | 0.443 | |
1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.443 | |
1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.443 | |
1xk9 | P34 | Exotoxin A | 2.4.2.36 | 0.443 | |
2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
3bi4 | 298 | Polyamine oxidase FMS1 | / | 0.443 | |
3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
3ggg | NAD | Prephenate dehydrogenase | / | 0.443 | |
3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.443 | |
3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
4jtd | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.443 | |
4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.443 | |
4xp4 | COC | Sodium-dependent dopamine transporter | / | 0.443 | |
5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.443 | |
1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
1ad3 | NAD | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.442 | |
1j8q | FMN | Flavodoxin | / | 0.442 | |
1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.442 | |
1ofv | FMN | Flavodoxin | / | 0.442 | |
1t4v | 14A | Prothrombin | 3.4.21.5 | 0.442 | |
1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.442 | |
1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
2a5c | 8DA | Avidin | / | 0.442 | |
2b51 | UTP | RNA editing complex protein MP57 | / | 0.442 | |
2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.442 | |
2ggq | TTP | Dual sugar-1-phosphate nucleotidylyltransferase | / | 0.442 | |
3c0z | SHH | Histone deacetylase 7 | 3.5.1.98 | 0.442 | |
3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.442 | |
3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
3gu3 | SAH | Methyltransferase | / | 0.442 | |
3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.442 | |
4es5 | MGT | Polymerase basic protein 2 | / | 0.442 | |
4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.442 | |
4tmc | FMN | Old yellow enzyme | / | 0.442 | |
4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
1aiq | CB3 | Thymidylate synthase | / | 0.441 | |
1d6w | 00R | Prothrombin | 3.4.21.5 | 0.441 | |
1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.441 | |
1srj | NAB | Streptavidin | / | 0.441 | |
1svl | ADP | Large T antigen | 3.6.4 | 0.441 | |
1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.441 | |
1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
1z48 | FMN | NADPH dehydrogenase | / | 0.441 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.441 | |
2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
2gg9 | U16 | Methionine aminopeptidase | / | 0.441 | |
2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
2hzq | STR | Apolipoprotein D | / | 0.441 | |
2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.441 | |
2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.441 | |
2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.441 | |
3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.441 | |
3vg9 | ZMA | Adenosine receptor A2a | / | 0.441 | |
3w5u | FAD | Ferredoxin | / | 0.441 | |
4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.441 | |
4ck2 | NVU | Integrase | / | 0.441 | |
4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
4hfp | 15U | Prothrombin | 3.4.21.5 | 0.441 | |
4j7h | TRH | PCZA361.3 | / | 0.441 | |
4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.441 | |
4q93 | STL | Tyrosine--tRNA ligase, cytoplasmic | 6.1.1.1 | 0.441 | |
4yfy | 1YJ | VioF | / | 0.441 | |
4yqf | GDP | Septin-9 | / | 0.441 | |
1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.440 | |
1p4a | PCP | Pur operon repressor | / | 0.440 | |
1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
1q13 | TES | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.440 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
1sre | HAB | Streptavidin | / | 0.440 | |
1srg | MHB | Streptavidin | / | 0.440 | |
1vft | DCS | Alanine racemase | / | 0.440 | |
2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.440 | |
2bdy | UNB | Prothrombin | 3.4.21.5 | 0.440 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.440 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
2j5x | GSP | ADP-ribosylation factor 6 | / | 0.440 | |
2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
2r2m | I50 | Prothrombin | 3.4.21.5 | 0.440 | |
2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
3arn | MSJ | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | 3.6.1.23 | 0.440 | |
3bgx | MEF | Thymidylate synthase | / | 0.440 | |
3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.440 | |
3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
3ung | ADP | CRISPR system Cmr subunit Cmr2 | / | 0.440 | |
3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.440 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.440 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.440 | |
4jv3 | N32 | Beta-ketoacyl synthase | / | 0.440 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
5dp2 | NAP | CurF | / | 0.440 |