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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wooTHGAminomethyltransferase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1wooTHGAminomethyltransferase/1.000
1wopFFOAminomethyltransferase/0.797
2nnqT4BFatty acid-binding protein, adipocyte/0.523
2ojg19AMitogen-activated protein kinase 12.7.11.240.513
3fazNOSPurine nucleoside phosphorylase/0.506
1xzqFONtRNA modification GTPase MnmE3.6.50.502
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.499
1lbbKAIGlutamate receptor 2/0.498
1towCRZFatty acid-binding protein, adipocyte/0.496
4bfxZVXPantothenate kinase2.7.1.330.495
3fhxPLPPyridoxal kinase2.7.1.350.494
3hy310F5-formyltetrahydrofolate cyclo-ligase6.3.3.20.493
2j2pSC2Ficolin-2/0.491
4twlASCDioscorin 5/0.491
2xupTZ5Acetylcholinesterase3.1.1.70.487
3hk1B64Fatty acid-binding protein, adipocyte/0.487
4g8jTHMUridine phosphorylase/0.487
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.486
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.486
4araC56Acetylcholinesterase3.1.1.70.485
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.484
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.484
4i6gFADCryptochrome-2/0.484
3bm1FMNPutative NAD(P)H nitroreductase YdjA/0.483
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.482
1ecb5GPAmidophosphoribosyltransferase/0.482
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
3ndjJHZMethyltransferase/0.481
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.480
4kxjP34Nucleoprotein/0.480
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.479
1fw0KAIGlutamate receptor 2/0.478
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.478
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.478
3owxXRARibosyldihydronicotinamide dehydrogenase [quinone]/0.478
4ey6GNTAcetylcholinesterase3.1.1.70.478
3o9pMHIPeriplasmic murein peptide-binding protein/0.477
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.477
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.477
1u1f183Uridine phosphorylase2.4.2.30.476
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.476
3br3ETHTH-type transcriptional regulator QacR/0.476
2bt4CA23-dehydroquinate dehydratase4.2.1.100.475
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.475
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.475
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.475
4yklGMPAprataxin-like protein30.475
3sn6P0GBeta-2 adrenergic receptor/0.475
1t57FMNConserved protein/0.474
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.474
4bqyFNTEgl nine homolog 1/0.474
4rp8ASCAscorbate-specific PTS system EIIC component/0.474
1ve3SAMUncharacterized protein/0.473
4jzr4JREgl nine homolog 1/0.473
1e2jTHMThymidine kinase/0.472
3rtnRTNBeta-secretase 13.4.23.460.472
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.471
1n5vNOMActVA 6 protein/0.471
1t4u81AProthrombin3.4.21.50.471
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.471
4rrgA3TThreonine--tRNA ligase6.1.1.30.471
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.471
2onfCOAUncharacterized protein/0.470
2whqHI6Acetylcholinesterase3.1.1.70.470
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3fr5I4AFatty acid-binding protein, adipocyte/0.470
3i0pNADMalate dehydrogenase, putative/0.470
3vilSA0Beta-glucosidase/0.470
4f3gKAIGlutamate receptor 3/0.470
2hl0A3SThreonine--tRNA ligase6.1.1.30.469
2zhe13UProthrombin3.4.21.50.469
1bcuPRLProthrombin3.4.21.50.468
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.468
2xjc5GPCytosolic purine 5'-nucleotidase3.1.3.50.468
2zgx29UProthrombin3.4.21.50.468
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.468
1vrqFONSubunit alpha of sarocosine oxidase/0.467
2qxxTTPdCTP deaminase3.5.4.130.467
3i2834NBifunctional epoxide hydrolase 23.3.2.100.467
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.467
5d4uSAMUncharacterized protein MJ0489/0.467
1odcA8BAcetylcholinesterase3.1.1.70.466
1sb1165Prothrombin3.4.21.50.466
2bn4FADNADPH--cytochrome P450 reductase/0.466
2clfF6FTryptophan synthase alpha chain/0.466
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.466
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.466
3gr8FMNNADPH dehydrogenase/0.466
3wquATPCell division protein FtsA/0.466
4cdmFO1Deoxyribodipyrimidine photolyase/0.466
4gg1TZDBenzoylformate decarboxylase4.1.1.70.466
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.465
2jh6894Prothrombin3.4.21.50.465
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.465
4jtrIZPAldo-keto reductase family 1 member C2/0.465
1cq7PY5Aspartate aminotransferase2.6.1.10.464
1dx6GNTAcetylcholinesterase3.1.1.70.464
1kziTHGThymidylate synthase/0.464
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.464
1yw8A75Methionine aminopeptidase 2/0.464
2zf051UProthrombin3.4.21.50.464
3h3sH15Collagen type IV alpha-3-binding protein/0.464
3qftFADNADPH--cytochrome P450 reductase/0.464
3vt3VDXVitamin D3 receptor/0.464
4arbC57Acetylcholinesterase3.1.1.70.464
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.463
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.463
1x8b824Wee1-like protein kinase2.7.10.20.463
1xr2C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase2.1.1.140.463
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.463
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.463
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.463
3junAJDPhenazine biosynthesis protein A/B/0.463
3klbFMNUncharacterized protein/0.463
3mauPLRPutative sphingosine-1-phosphate lyase/0.463
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.463
4yao2AMNADPH--cytochrome P450 reductase/0.463
1ae8AZLProthrombin3.4.21.50.462
1o6qR17Squalene--hopene cyclase4.2.1.1290.462
1pq944BOxysterols receptor LXR-beta/0.462
1txtCAAHMG-CoA synthase/0.462
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.462
2xuhTZ4Acetylcholinesterase3.1.1.70.462
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.462
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.462
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.462
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.462
3rsv3RSBeta-secretase 13.4.23.460.462
3zc3FADFerredoxin--NADP reductase1.18.1.20.462
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.462
1touB1VFatty acid-binding protein, adipocyte/0.461
2gvdFKPAdenylate cyclase type 2/0.461
2gvdFKPAdenylate cyclase type 5/0.461
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.461
3c27DKKProthrombin3.4.21.50.461
3lzzGDPUncharacterized protein/0.461
3p1799PProthrombin3.4.21.50.461
3qto10PProthrombin3.4.21.50.461
4a16H34Acetylcholinesterase3.1.1.70.461
4bfyZVYPantothenate kinase2.7.1.330.461
4n1gCEIObelin/0.461
4xbfFADLysine-specific histone demethylase 1A10.461
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.460
1xddAAYIntegrin alpha-L/0.460
2cjfRP43-dehydroquinate dehydratase4.2.1.100.460
2vqjTFGHistone deacetylase 43.5.1.980.460
2zdv37UProthrombin3.4.21.50.460
3dr7GPDGDP-perosamine synthase/0.460
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.460
4fpy0V8Sialidase B3.2.1.180.460
5dn1AMZPhosphoribosyl isomerase A5.3.1.160.460
1o2eANNPhospholipase A23.1.1.40.459
1ppjANYCytochrome b/0.459
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.459
1zgbA1EAcetylcholinesterase3.1.1.70.459
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.459
2ha6SCKAcetylcholinesterase3.1.1.70.459
2vd4P21Bifunctional protein GlmU/0.459
3lzxNAPFerredoxin--NADP reductase 21.18.1.20.459
4xxvNAD3-isopropylmalate dehydrogenase/0.459
1a9cGTPGTP cyclohydrolase 13.5.4.160.458
1nzq162Prothrombin3.4.21.50.458
1q84TZ4Acetylcholinesterase3.1.1.70.458
1trgCB3Thymidylate synthase/0.458
2futH1SHeparin and heparin-sulfate lyase/0.458
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.458
2xuoTZ4Acetylcholinesterase3.1.1.70.458
3aosJH2Hemolymph juvenile hormone binding protein/0.458
3ihzFK5Peptidylprolyl isomerase/0.458
3vf60H6Glucokinase2.7.1.20.458
4b66NAPL-ornithine N(5)-monooxygenase/0.458
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4hc4SAHProtein arginine N-methyltransferase 6/0.458
4rrrA3TThreonine--tRNA ligase6.1.1.30.458
5cmx0G6Prothrombin3.4.21.50.458
1mraAPGMandelate racemase/0.457
2op18PCEnoyl-ACP reductase/0.457
2zhw12UProthrombin3.4.21.50.457
3fp0FP015-O-acetyltransferase/0.457
3gx9TXDMorphinone reductase/0.457
4bfuZVUPantothenate kinase2.7.1.330.457
5fm7ADPRuvB-like helicase/0.457
1gaxVAAValine--tRNA ligase6.1.1.90.456
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.456
1zgv501Prothrombin3.4.21.50.456
2xukTZ5Acetylcholinesterase3.1.1.70.456
3c35KAIGlutamate receptor ionotropic, kainate 1/0.456
3e6eDCSAlanine racemase/0.456
3own3OWRenin3.4.23.150.456
3p0hFSEPutative tyrosyl-tRNA synthetase/0.456
3rviRVIBeta-secretase 13.4.23.460.456
3ufl508Beta-secretase 13.4.23.460.456
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.456
4iilRBFMembrane lipoprotein TpN38(b)/0.456
1d9i00PProthrombin3.4.21.50.455
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.455
2b82ADNClass B acid phosphatase3.1.3.20.455
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.455
3junAKDPhenazine biosynthesis protein A/B/0.455
3lutNAPVoltage-gated potassium channel subunit beta-2/0.455
3nu03TUDihydrofolate reductase1.5.1.30.455
3wqtANPCell division protein FtsA/0.455
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.455
4ey7E20Acetylcholinesterase3.1.1.70.455
4kc1WS1Histo-blood group ABO system transferase/0.455
4mlp2CXCryptochrome-2/0.455
1ao05GPAmidophosphoribosyltransferase/0.454
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.454
1gjrFADFerredoxin--NADP reductase1.18.1.20.454
1kceCB3Thymidylate synthase/0.454
1pfyMSPMethionine--tRNA ligase6.1.1.100.454
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.454
2iluNDPLactaldehyde dehydrogenase1.2.1.220.454
3fr4F8AFatty acid-binding protein, adipocyte/0.454
3lxeTORCarbonic anhydrase 14.2.1.10.454
3pl8FADPyranose 2-oxidase/0.454
3v0m5GWHisto-blood group ABO system transferase/0.454
1cq6PY4Aspartate aminotransferase2.6.1.10.453
1h60STRPentaerythritol tetranitrate reductase/0.453
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.453
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2nm2NEUDihydroneopterin aldolase/0.453
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.453
3cnpSP7Polyamine oxidase FMS1/0.453
3lnmNAPVoltage-gated potassium channel subunit beta-2/0.453
3qtv06PProthrombin3.4.21.50.453
3rbaCODPhosphopantetheine adenylyltransferase/0.453
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.453
4e32DWNMethyltransferase/0.453
1ay0TPPTransketolase 12.2.1.10.452
1xuzMMNCapsule biosynthesis protein/0.452
2gyuHI6Acetylcholinesterase3.1.1.70.452
2jh5895Prothrombin3.4.21.50.452
2owfSAHDiphthine synthase/0.452
2w6cBM4Acetylcholinesterase3.1.1.70.452
2z95NDPGDP-mannose 4,6-dehydratase/0.452
2zevB71Geranylgeranyl pyrophosphate synthase/0.452
4g090VDHistidinol dehydrogenase/0.452
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.452
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.452
4u8iFDAUDP-galactopyranose mutase/0.452
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.451
1mueCDDProthrombin3.4.21.50.451
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
1sbzFMNProbable UbiX-like flavin prenyltransferase/0.451
2nr4FMNConserved protein/0.451
2zsbADPPantothenate kinase2.7.1.330.451
3c36KAIGlutamate receptor ionotropic, kainate 1/0.451
3kapFMNFlavodoxin/0.451
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.451
3ts1TYATyrosine--tRNA ligase6.1.1.10.451
4dy4FMNNAD(P)H dehydrogenase (quinone)/0.451
4m0f1YKAcetylcholinesterase3.1.1.70.451
4mv1ADPBiotin carboxylase6.3.4.140.451
4q72FADBifunctional protein PutA/0.451
1hfqMOTDihydrofolate reductase1.5.1.30.450
1n3rGTPGTP cyclohydrolase 13.5.4.160.450
1tkaN3TTransketolase 12.2.1.10.450
1w6jR71Lanosterol synthase5.4.99.70.450
2c3yHTLPyruvate synthase/0.450
2hxzH7JCathepsin S3.4.22.270.450
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
3arqDM5Chitinase A/0.450
3bi6396Wee1-like protein kinase2.7.10.20.450
4gekGEKCarboxy-S-adenosyl-L-methionine synthase/0.450
4jq3ZOMAldo-keto reductase family 1 member C2/0.450
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.450
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.450
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.449
1gj5130Prothrombin3.4.21.50.449
1lb9DNQGlutamate receptor 2/0.449
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.449
1tkcM6TTransketolase 12.2.1.10.449
1toiHCIAspartate aminotransferase2.6.1.10.449
2acwUPGGlycosyltransferase/0.449
2jf0HBPAcetylcholinesterase3.1.1.70.449
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.449
3kdiA8SAbscisic acid receptor PYL2/0.449
4du6GTPGTP cyclohydrolase 1/0.449
1a4wQWEProthrombin3.4.21.50.448
1afeALZProthrombin3.4.21.50.448
1e2nRCAThymidine kinase/0.448
1ftlDNQGlutamate receptor 2/0.448
1r58AO5Methionine aminopeptidase 2/0.448
1rfuPLPPyridoxal kinase2.7.1.350.448
1x2hLPALipoate-protein ligase A6.3.1.200.448
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.448
2pncCLUPrimary amine oxidase, liver isozyme/0.448
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.448
3af4GCPPantothenate kinase2.7.1.330.448
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.448
3fktSIIBeta-secretase 13.4.23.460.448
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.448
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
4bftZVTPantothenate kinase2.7.1.330.448
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.448
4c02TAKActivin receptor type-12.7.11.300.448
4dbc3QPAspartate aminotransferase2.6.1.10.448
4oztP1AEcdysone receptor, putative/0.448
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.448
5cvfATPCasein kinase II subunit alpha2.7.11.10.448
1ij8BNIAvidin/0.447
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.447
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.447
2c3u2TPPyruvate synthase/0.447
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.447
3juqAJDPhenazine biosynthesis protein A/B/0.447
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.447
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.447
4fm80UQBeta-secretase 13.4.23.460.447
4isuIKMGlutamate receptor 2/0.447
4y1bNAPAntE/0.447
1g9cBABBotulinum neurotoxin type B3.4.24.690.446
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.10.446
1o2g696Prothrombin3.4.21.50.446
1ypeUIPProthrombin3.4.21.50.446
1zgi382Prothrombin3.4.21.50.446
2ejzSAHDiphthine synthase/0.446
2gg2U12Methionine aminopeptidase/0.446
2mokFMNFlavodoxin 1/0.446
2pdaTPPPyruvate synthase/0.446
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.446
2vz0D64Pteridine reductase/0.446
2wu4HBPAcetylcholinesterase3.1.1.70.446
2zhq27UProthrombin3.4.21.50.446
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.446
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.446
4b6r3DQ3-dehydroquinate dehydratase4.2.1.100.446
4b7zQ4QAcetylcholinesterase3.1.1.70.446
4c72TLG3-oxoacyl-ACP synthase/0.446
4jvlESTEstrogen sulfotransferase2.8.2.40.446
4nbb9CATerminal oxygenase component of carbazole/0.446
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.446
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.445
1n5qTNCActVA 6 protein/0.445
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.445
1xvvCCQL-carnitine CoA-transferase/0.445
1z3cSA8mRNA cap guanine-N7 methyltransferase2.1.1.560.445
1z6tADPApoptotic protease-activating factor 1/0.445
2gg3U13Methionine aminopeptidase/0.445
2onyTMJPhenylethanolamine N-methyltransferase2.1.1.280.445
2x06NADL-sulfolactate dehydrogenase/0.445
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.445
3arpDEQChitinase A/0.445
3bi2FADPolyamine oxidase FMS1/0.445
3h1vTK1Glucokinase2.7.1.20.445
3h3r14HCollagen type IV alpha-3-binding protein/0.445
3nf8CDQGag-Pol polyprotein/0.445
3qwpSAMHistone-lysine N-methyltransferase SMYD32.1.1.430.445
3rthRTHBeta-secretase 13.4.23.460.445
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.445
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.445
4az29MUProthrombin3.4.21.50.445
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.445
4bfsZVSPantothenate kinase2.7.1.330.445
4c73TLH3-oxoacyl-ACP synthase/0.445
4p9dTMPDeoxycytidylate deaminase/0.445
4y7cFMNNADPH--cytochrome P450 reductase/0.445
1cgzSTLChalcone synthase 22.3.1.740.444
1d3dBZTProthrombin3.4.21.50.444
1ja0FADNADPH--cytochrome P450 reductase/0.444
1jwtBLIProthrombin3.4.21.50.444
1knpFADL-aspartate oxidase1.4.3.160.444
1ogiFADFerredoxin--NADP reductase1.18.1.20.444
1olsTDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.444
1rzuADPGlycogen synthase 12.4.1.210.444
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.444
1w1vALJChitinase/0.444
1ypkCCRProthrombin3.4.21.50.444
2geuCOKPantothenate kinase2.7.1.330.444
2hwuURIUridine phosphorylase2.4.2.30.444
2qcxPF1Aminopyrimidine aminohydrolase/0.444
2xgoZKDUncharacterized protein/0.444
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.444
3fpkFADFerredoxin-NADP reductase/0.444
3jqrFADFerredoxin--NADP reductase, apicoplast/0.444
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.444
4l7vSAHProtein-L-isoaspartate O-methyltransferase/0.444
4rrfA3SThreonine--tRNA ligase6.1.1.30.444
4xzjNADPutative NAD(+)--arginine ADP-ribosyltransferase Vis2.4.2.310.444
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.443
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1c4yIH3Prothrombin3.4.21.50.443
1clqGDPDNA-directed DNA polymerase/0.443
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.443
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.443
1x2eATXProline iminopeptidase3.4.11.50.443
1xk9P34Exotoxin A2.4.2.360.443
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.443
2w6qOA5Biotin carboxylase6.3.4.140.443
2xujTZ5Acetylcholinesterase3.1.1.70.443
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
3bi4298Polyamine oxidase FMS1/0.443
3fsjD7KBenzoylformate decarboxylase4.1.1.70.443
3gggNADPrephenate dehydrogenase/0.443
3l7gM44Xaa-Pro dipeptidase3.4.13.90.443
3nhuM42Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
3nxvD2FDihydrofolate reductase1.5.1.30.443
3sfh1DIHistone deacetylase 83.5.1.980.443
3zv7NHGAcetylcholinesterase3.1.1.70.443
4jtdNAPVoltage-gated potassium channel subunit beta-2/0.443
4stdBFSScytalone dehydratase4.2.1.940.443
4x9dU5PUncharacterized protein MJ1435/0.443
4xp4COCSodium-dependent dopamine transporter/0.443
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.443
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.442
1ad3NADAldehyde dehydrogenase, dimeric NADP-preferring/0.442
1j8qFMNFlavodoxin/0.442
1mc1PCXCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.442
1ofvFMNFlavodoxin/0.442
1t4v14AProthrombin3.4.21.50.442
1yplRA8Prothrombin3.4.21.50.442
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2a5c8DAAvidin/0.442
2b51UTPRNA editing complex protein MP57/0.442
2ea1GPGRibonuclease I3.1.27.60.442
2ggqTTPDual sugar-1-phosphate nucleotidylyltransferase/0.442
3c0zSHHHistone deacetylase 73.5.1.980.442
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.442
3fr28CAFatty acid-binding protein, adipocyte/0.442
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.442
3gu3SAHMethyltransferase/0.442
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
4es5MGTPolymerase basic protein 2/0.442
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.442
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.442
4tmcFMNOld yellow enzyme/0.442
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.442
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.442
1aiqCB3Thymidylate synthase/0.441
1d6w00RProthrombin3.4.21.50.441
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.441
1esmCOAPantothenate kinase2.7.1.330.441
1srjNABStreptavidin/0.441
1svlADPLarge T antigen3.6.40.441
1tkbN1TTransketolase 12.2.1.10.441
1tojHCIAspartate aminotransferase2.6.1.10.441
1z48FMNNADPH dehydrogenase/0.441
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.441
2cmfF11Acetylcholinesterase3.1.1.70.441
2gg9U16Methionine aminopeptidase/0.441
2hkoFADLysine-specific histone demethylase 1A10.441
2hzqSTRApolipoprotein D/0.441
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.441
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.441
2vn1FK5Peptidylprolyl isomerase/0.441
3eq02TSProthrombin3.4.21.50.441
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.441
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.441
3v0o4GWHisto-blood group ABO system transferase/0.441
3vg9ZMAAdenosine receptor A2a/0.441
3w5uFADFerredoxin/0.441
4b4vL34Bifunctional protein FolD/0.441
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.441
4ck2NVUIntegrase/0.441
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
4hfp15UProthrombin3.4.21.50.441
4j7hTRHPCZA361.3/0.441
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.441
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.441
4q93STLTyrosine--tRNA ligase, cytoplasmic6.1.1.10.441
4yfy1YJVioF/0.441
4yqfGDPSeptin-9/0.441
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.440
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.440
1p4aPCPPur operon repressor/0.440
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.440
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.440
1qoqIGPTryptophan synthase alpha chain/0.440
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.440
1sreHABStreptavidin/0.440
1srgMHBStreptavidin/0.440
1vftDCSAlanine racemase/0.440
2a3bCFFEndochitinase B13.2.1.140.440
2bdyUNBProthrombin3.4.21.50.440
2ea2F77Methionine aminopeptidase 2/0.440
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2hdjNDPAldo-keto reductase family 1 member C2/0.440
2j5xGSPADP-ribosylation factor 6/0.440
2ji7ADPOxalyl-CoA decarboxylase4.1.1.80.440
2r2mI50Prothrombin3.4.21.50.440
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2vq7NAPPutative flavin-containing monooxygenase/0.440
3arnMSJDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial3.6.1.230.440
3bgxMEFThymidylate synthase/0.440
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.440
3q9bB3NAcetylpolyamine amidohydrolase/0.440
3udk095Beta-secretase 13.4.23.460.440
3ungADPCRISPR system Cmr subunit Cmr2/0.440
3vo2FADFerredoxin--NADP reductase/0.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4ih71ERGenome polyprotein2.7.7.480.440
4imfSI3N-acetylneuraminate lyase/0.440
4jv3N32Beta-ketoacyl synthase/0.440
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
5dp2NAPCurF/0.440