sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wma | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1wma | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 1.000 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.524 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.510 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.507 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.504 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.504 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.502 | |
| 3bhm | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.501 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.500 | |
| 1jje | BYS | Beta-lactamase | / | 0.498 | |
| 4cjw | CBJ | Integrase | / | 0.498 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.497 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.496 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.494 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.494 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.494 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.489 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.489 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.488 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.488 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.487 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.486 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.485 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.485 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.485 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.484 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.484 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.484 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.483 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.483 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.483 | |
| 3bhm | AHE | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.482 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.482 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.482 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.482 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.482 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.481 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.480 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.480 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.480 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.480 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.479 | |
| 1sqb | AZO | Cytochrome b | / | 0.479 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.479 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.478 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.478 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.477 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.477 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.477 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.477 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.476 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.476 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.476 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.475 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.475 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.474 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.474 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.474 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.473 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.473 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.472 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.472 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.471 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3lcv | SAM | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.471 | |
| 3thy | ADP | DNA mismatch repair protein Msh2 | / | 0.471 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.471 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.471 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.470 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.470 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.470 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.470 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.470 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.469 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.469 | |
| 1stp | BTN | Streptavidin | / | 0.469 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.469 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.469 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.469 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.468 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.468 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.468 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.468 | |
| 1swt | BTN | Streptavidin | / | 0.467 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.467 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.467 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.467 | |
| 3l70 | JZV | Cytochrome b | / | 0.467 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.467 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.467 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.466 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 4f6s | 0SQ | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.466 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.466 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.466 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.465 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.465 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.465 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.465 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.465 | |
| 1avd | BTN | Avidin | / | 0.464 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.464 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.464 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.464 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.464 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.464 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.464 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.464 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.464 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.463 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.463 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.463 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.463 | |
| 3p9t | TCL | Repressor | / | 0.463 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.463 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.463 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.463 | |
| 4iae | 1DX | Alr2278 protein | / | 0.463 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.463 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.463 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.462 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.462 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.462 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.462 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.462 | |
| 2rgc | GNP | GTPase HRas | / | 0.462 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.462 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.462 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.462 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.461 | |
| 2uvy | GVI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.461 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.461 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.461 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.461 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.460 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.460 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.460 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.460 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.460 | |
| 3ql6 | NIM | Lactoperoxidase | 1.11.1.7 | 0.460 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.460 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.460 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.460 | |
| 5dp2 | NAP | CurF | / | 0.460 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.459 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.459 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.459 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.459 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.459 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.459 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4l4x | NDP | AmphI | / | 0.459 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 4qpz | TPP | Benzaldehyde lyase | / | 0.459 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.459 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.458 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.458 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.458 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.458 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.458 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.458 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.458 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4cry | ACO | PanD regulatory factor | / | 0.458 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.458 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.458 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.458 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.458 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 1sqp | MYX | Cytochrome b | / | 0.457 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.457 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.457 | |
| 2won | ZZE | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.457 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.457 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.457 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.457 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.456 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.456 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.456 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.456 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.456 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.456 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 1k0c | GTB | Transcriptional regulator URE2 | / | 0.455 | |
| 1swr | BTN | Streptavidin | / | 0.455 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.455 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.455 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.455 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.455 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.455 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 3qly | 55V | Uncharacterized protein | / | 0.455 | |
| 4iah | 1DX | Alr2278 protein | / | 0.455 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.455 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.455 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.455 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.454 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.454 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.454 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.454 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.454 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.454 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.454 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.454 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.454 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.454 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.454 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.454 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 3up0 | D7S | aceDAF-12 | / | 0.454 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.454 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.454 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.454 | |
| 1ddt | APU | Diphtheria toxin | / | 0.453 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.453 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 2igx | A1T | Plasmepsin 2 | / | 0.453 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.453 | |
| 2mm3 | CHO | Gastrotropin | / | 0.453 | |
| 2rti | GLL | Streptavidin | / | 0.453 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.453 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.453 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3l71 | AZO | Cytochrome b | / | 0.453 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.453 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.453 | |
| 4exs | X8Z | Metallo-beta-lactamase type 2 | / | 0.453 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.453 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.453 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.453 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.453 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.453 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.453 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.452 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.452 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.452 | |
| 1nsy | ATP | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.452 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.452 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.452 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2r04 | W71 | Genome polyprotein | / | 0.452 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.452 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.452 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.452 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.452 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.452 | |
| 3dol | GWI | Pol protein | / | 0.452 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.452 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.452 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.452 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 1e7a | PFL | Serum albumin | / | 0.451 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.451 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.451 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.451 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.451 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.451 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.451 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 3ry2 | BTN | Streptavidin | / | 0.451 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.451 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.451 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.451 | |
| 4hfn | CIY | 2-alkenal reductase (NADP(+)-dependent) | / | 0.451 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1jjt | BDS | Beta-lactamase | / | 0.450 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.450 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1uys | H1L | Acetyl-CoA carboxylase | / | 0.450 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.450 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.450 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.450 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.450 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.450 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.450 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.450 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4o6f | SAH | N-lysine methyltransferase SMYD2 | / | 0.450 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.449 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1sre | HAB | Streptavidin | / | 0.449 | |
| 1zdw | FLV | Prenyltransferase | / | 0.449 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 2bxq | IMN | Serum albumin | / | 0.449 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 2izh | BTN | Streptavidin | / | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.449 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.449 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.449 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.449 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 4o4e | ATP | Kinase | / | 0.449 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.448 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.448 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.448 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.448 | |
| 2fto | TMP | Thymidylate synthase | / | 0.448 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.448 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.448 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.448 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4jap | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.448 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.447 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.447 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.447 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.447 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.447 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.447 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.447 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.447 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.447 | |
| 3wzn | BTN | Streptavidin | / | 0.447 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.447 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.447 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 4ydq | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.447 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.447 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.447 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1dtp | APU | Diphtheria toxin | / | 0.446 | |
| 1srj | NAB | Streptavidin | / | 0.446 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.446 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.446 | |
| 1yvf | PH7 | Polyprotein | / | 0.446 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.446 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.446 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.446 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3eku | CY9 | Actin-5C | / | 0.446 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.446 | |
| 3up3 | XCA | aceDAF-12 | / | 0.446 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.446 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.446 | |
| 1bpw | NAD | Betaine aldehyde dehydrogenase | 1.2.1.8 | 0.445 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.445 | |
| 1e2j | THM | Thymidine kinase | / | 0.445 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1osv | CHC | Bile acid receptor | / | 0.445 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1srf | MTB | Streptavidin | / | 0.445 | |
| 2avi | BTN | Avidin | / | 0.445 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.445 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.445 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.445 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3p9k | CIY | Caffeic acid O-methyltransferase | / | 0.445 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.445 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4dlx | GNP | GTPase HRas | / | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.445 | |
| 4nvk | 2NY | Peroxidase | / | 0.445 | |
| 4oxi | GAP | Enterobactin synthetase component F-related protein | / | 0.445 | |
| 4phl | PIL | Phosphodiesterase | / | 0.445 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.444 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1srh | MOB | Streptavidin | / | 0.444 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.444 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.444 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3fxu | TSU | HTH-type transcriptional regulator TsaR | / | 0.444 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.444 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.444 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.444 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.444 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.444 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.443 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.443 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.443 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.443 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.443 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.443 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 2rtf | BTN | Streptavidin | / | 0.443 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.443 | |
| 3h1j | SMA | Cytochrome b | / | 0.443 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.443 | |
| 4cf8 | V7H | Integrase | / | 0.443 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.443 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.443 | |
| 1hnh | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.442 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.442 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.442 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.442 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.442 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3nfr | EWQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3nj8 | NJ8 | Enoyl-acyl carrier reductase | / | 0.442 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.442 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.442 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.442 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.442 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.442 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.442 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 4lde | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.441 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.441 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.441 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.441 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.441 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2izf | BTN | Streptavidin | / | 0.441 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.441 | |
| 2qe2 | 452 | Polyprotein | / | 0.441 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.441 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.441 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 3qcz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.441 | |
| 3rsl | GNP | GTPase HRas | / | 0.441 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
| 3zy5 | GFB | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.441 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.441 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.441 | |
| 5fit | AP2 | Bis(5'-adenosyl)-triphosphatase | 3.6.1.29 | 0.441 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.440 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1tys | DHF | Thymidylate synthase | / | 0.440 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1wa5 | GTP | GTP-binding nuclear protein Ran | / | 0.440 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.440 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.440 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.440 | |
| 3bgv | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.440 | |
| 3bhr | THG | Thymidylate synthase | / | 0.440 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3i4l | ANP | V-type ATP synthase alpha chain | 3.6.3.14 | 0.440 | |
| 3k31 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.440 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.440 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.440 | |
| 3zln | H0Y | Bcl-2-like protein 1 | / | 0.440 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.440 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 |