sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1w83 | L11 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.537 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.513 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.506 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.502 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.502 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.501 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.497 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.489 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.487 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.484 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.483 | |
| 3p9t | TCL | Repressor | / | 0.483 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.483 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.480 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.479 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.475 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.475 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.474 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.474 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.474 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.474 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.473 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.471 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.471 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.470 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.470 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.469 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.465 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3eel | 53T | Uncharacterized protein | / | 0.463 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.461 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.461 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.460 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.460 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.459 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.459 | |
| 1p7t | ACO | Malate synthase G | / | 0.459 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.459 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.459 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.459 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.458 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.458 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.456 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.456 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.456 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.456 | |
| 4phl | PIL | Phosphodiesterase | / | 0.456 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.455 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.455 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.454 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.454 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.454 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.454 | |
| 1c7o | PPG | Hemolysin | / | 0.453 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.453 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.453 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.452 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.452 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.452 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.452 | |
| 3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.452 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.452 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.452 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.451 | |
| 3cse | N22 | Uncharacterized protein | / | 0.451 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.451 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.451 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.451 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.450 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.450 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.450 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.449 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.449 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.449 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.449 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.448 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3qly | 55V | Uncharacterized protein | / | 0.448 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.448 | |
| 1n8w | COA | Malate synthase G | / | 0.447 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.447 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.447 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.447 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.447 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.446 | |
| 1t9b | 1CS | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.446 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.446 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3l70 | JZV | Cytochrome b | / | 0.446 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.446 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.446 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.446 | |
| 2p15 | EZT | Estrogen receptor | / | 0.445 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.445 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.445 | |
| 4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.445 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.445 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.444 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.444 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.444 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.444 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.444 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.444 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.443 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.443 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3htj | ET | EbrA repressor | / | 0.443 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.443 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.443 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 4ec3 | REN | Reticuline oxidase | 1.21.3.3 | 0.443 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.443 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.443 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3aba | FLI | Cytochrome P450 | / | 0.442 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.442 | |
| 3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.442 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4eyj | N61 | Mitogen-activated protein kinase 13 | 2.7.11.24 | 0.442 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.441 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.441 | |
| 3saz | 043 | Malate synthase G | / | 0.441 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.441 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.441 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.441 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.441 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.441 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.440 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.440 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.440 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4pd6 | URI | Nucleoside permease | / | 0.440 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.440 |