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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1w82L10Mitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1w82L10Mitogen-activated protein kinase 14/1.000
3d83GK6Mitogen-activated protein kinase 14/0.578
3nnwEDDMitogen-activated protein kinase 14/0.574
1wbnL09Mitogen-activated protein kinase 14/0.567
1wbtWBTMitogen-activated protein kinase 14/0.535
3e9319BMitogen-activated protein kinase 14/0.526
1wbsLI2Mitogen-activated protein kinase 14/0.524
3nnxEDDMitogen-activated protein kinase 14/0.497
3nnuEDBMitogen-activated protein kinase 14/0.491
3kq7KQ7Mitogen-activated protein kinase 14/0.487
1wbvLI3Mitogen-activated protein kinase 14/0.486
3hv4L51Mitogen-activated protein kinase 14/0.477
3uvr06FMitogen-activated protein kinase 14/0.477
2yisYISMitogen-activated protein kinase 14/0.468
3npcB96Mitogen-activated protein kinase 92.7.11.240.457
3p7bP7BMitogen-activated protein kinase 14/0.453
3lffZ83Mitogen-activated protein kinase 14/0.452
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3p7cP7CMitogen-activated protein kinase 14/0.440