Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1w82 | L10 | Mitogen-activated protein kinase 14 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1w82 | L10 | Mitogen-activated protein kinase 14 | / | 1.000 | |
3d83 | GK6 | Mitogen-activated protein kinase 14 | / | 0.578 | |
3nnw | EDD | Mitogen-activated protein kinase 14 | / | 0.574 | |
1wbn | L09 | Mitogen-activated protein kinase 14 | / | 0.567 | |
1wbt | WBT | Mitogen-activated protein kinase 14 | / | 0.535 | |
3e93 | 19B | Mitogen-activated protein kinase 14 | / | 0.526 | |
1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.524 | |
3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.497 | |
3nnu | EDB | Mitogen-activated protein kinase 14 | / | 0.491 | |
3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.487 | |
1wbv | LI3 | Mitogen-activated protein kinase 14 | / | 0.486 | |
3hv4 | L51 | Mitogen-activated protein kinase 14 | / | 0.477 | |
3uvr | 06F | Mitogen-activated protein kinase 14 | / | 0.477 | |
2yis | YIS | Mitogen-activated protein kinase 14 | / | 0.468 | |
3npc | B96 | Mitogen-activated protein kinase 9 | 2.7.11.24 | 0.457 | |
3p7b | P7B | Mitogen-activated protein kinase 14 | / | 0.453 | |
3lff | Z83 | Mitogen-activated protein kinase 14 | / | 0.452 | |
3ml9 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
3p7c | P7C | Mitogen-activated protein kinase 14 | / | 0.440 |