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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.78

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.781.000
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.608
1w19T4P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.576
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.549
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.547
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.531
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.511
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.507
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.498
2c9bPUG6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.497
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.491
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.489
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.482
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.476
1w29TS16,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.458
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.454
2c97JCL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.440