sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vg8 | GNP | Ras-related protein Rab-7a |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 1.000 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.622 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.608 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.606 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.600 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.594 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.587 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.587 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.585 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.579 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.548 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.522 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.519 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.519 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.518 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.518 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.507 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.507 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.505 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.504 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.502 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.500 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.496 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.491 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.488 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.481 | |
| 3lbn | GNP | GTPase HRas | / | 0.481 | |
| 3rs5 | GNP | GTPase HRas | / | 0.481 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.478 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.478 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.470 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.470 | |
| 3oiv | GNP | GTPase HRas | / | 0.470 | |
| 5b2z | GNP | GTPase HRas | / | 0.468 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.465 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.465 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.465 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.463 | |
| 4dlt | GNP | GTPase HRas | / | 0.462 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.459 | |
| 4dlw | GNP | GTPase HRas | / | 0.456 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.455 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.453 | |
| 3v4f | GNP | GTPase HRas | / | 0.453 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.450 | |
| 2c5l | GTP | GTPase HRas | / | 0.449 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.448 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.448 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.447 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.446 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.445 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.444 | |
| 3i3s | GNP | GTPase HRas | / | 0.444 | |
| 3kud | GDP | GTPase HRas | / | 0.443 | |
| 3ddc | GNP | GTPase HRas | / | 0.441 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.441 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.441 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.440 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.440 |