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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.9

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.91.000
3d8xFADThioredoxin reductase 11.8.1.90.531
4a65FADThioredoxin reductase/0.503
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
1c0lFADD-amino-acid oxidase1.4.3.30.440
4xwzFADFructosyl amine:oxygen oxidoreductase/0.440