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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1v0pPVBCell division control protein 2 homolog2.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1v0pPVBCell division control protein 2 homolog2.7.11.221.000
2r64740Cyclin-dependent kinase 22.7.11.220.543
3lfqA28Cyclin-dependent kinase 22.7.11.220.523
1ckpPVBCyclin-dependent kinase 22.7.11.220.497
3r9dX6BCyclin-dependent kinase 22.7.11.220.491
1gih1PUCyclin-dependent kinase 22.7.11.220.488
3s2pPMUCyclin-dependent kinase 22.7.11.220.488
2uznC96Cyclin-dependent kinase 22.7.11.220.486
2w05FRTCyclin-dependent kinase 22.7.11.220.485
3le62BZCyclin-dependent kinase 22.7.11.220.485
4fkpLS5Cyclin-dependent kinase 22.7.11.220.475
2wotZZGTGF-beta receptor type-12.7.11.300.474
2ds11CDCyclin-dependent kinase 22.7.11.220.472
2w1hL0FCyclin-dependent kinase 22.7.11.220.467
2j9mPY8Cyclin-dependent kinase 22.7.11.220.466
3lfsA07Cyclin-dependent kinase 22.7.11.220.466
3qwjX6ACyclin-dependent kinase 22.7.11.220.466
2iw84SPCyclin-dependent kinase 22.7.11.220.465
4cfnJYMCyclin-dependent kinase 22.7.11.220.462
3r7iX9ICyclin-dependent kinase 22.7.11.220.460
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
2btsU32Cyclin-dependent kinase 22.7.11.220.458
2uzlC94Cyclin-dependent kinase 22.7.11.220.458
4fkg4CKCyclin-dependent kinase 22.7.11.220.458
2iw94SPCyclin-dependent kinase 22.7.11.220.455
2fvdLIACyclin-dependent kinase 22.7.11.220.454
2x1nX1NCyclin-dependent kinase 22.7.11.220.454
3ddpRC8Cyclin-dependent kinase 22.7.11.220.454
3rni21ZCyclin-dependent kinase 22.7.11.220.454
4ek610KCyclin-dependent kinase 22.7.11.220.453
1oirHDYCyclin-dependent kinase 22.7.11.220.452
4eor4SPCyclin-dependent kinase 22.7.11.220.452
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.451
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.450
2duv371Cyclin-dependent kinase 22.7.11.220.449
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.449
1unlRRCCyclin-dependent-like kinase 52.7.11.10.447
2r3iSCFCyclin-dependent kinase 22.7.11.220.447
3r1sX73Cyclin-dependent kinase 22.7.11.220.447
4ez50RSCyclin-dependent kinase 62.7.11.220.447
2vtrLZBCyclin-dependent kinase 22.7.11.220.445
4fkt48KCyclin-dependent kinase 22.7.11.220.445
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
3uli1N3Cyclin-dependent kinase 22.7.11.220.444
4erwSTUCyclin-dependent kinase 22.7.11.220.444
1g5sI17Cyclin-dependent kinase 22.7.11.220.443
1oguST8Cyclin-dependent kinase 22.7.11.220.443
1vyw292Cyclin-dependent kinase 22.7.11.220.443
3rk507ZCyclin-dependent kinase 22.7.11.220.443
1aq1STUCyclin-dependent kinase 22.7.11.220.442
3qwkX62Cyclin-dependent kinase 22.7.11.220.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
1vyzN5BCyclin-dependent kinase 22.7.11.220.441
3qrtX14Cyclin-dependent kinase 22.7.11.220.441
3qtzX42Cyclin-dependent kinase 22.7.11.220.441
1h0w207Cyclin-dependent kinase 22.7.11.220.440
3r73X87Cyclin-dependent kinase 22.7.11.220.440