sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uxj | NAD | Malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1uxj | NAD | Malate dehydrogenase | / | 1.000 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.576 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.509 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.507 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.493 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.491 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.483 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.477 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.474 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.474 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.474 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.469 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.467 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 4ros | APR | Malate dehydrogenase | / | 0.458 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.450 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 |