sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1us0 | LDT | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 1.000 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.829 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.791 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.770 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.762 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.762 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.741 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.735 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.729 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.721 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.721 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.718 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.712 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.706 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.670 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.670 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.666 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.663 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.661 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.654 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.652 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.651 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.649 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.643 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.640 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.639 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.636 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.629 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.624 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.623 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.621 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.617 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.616 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.614 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.607 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.602 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.602 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.594 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.594 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.593 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.591 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.586 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.582 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.576 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.573 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.573 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.568 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.568 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.567 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.564 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.563 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.555 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.550 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.538 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.509 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.507 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.504 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.499 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.498 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.497 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.496 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.496 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.496 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.494 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.494 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.494 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.490 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.489 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.487 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.486 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.485 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 1rxj | BNI | Streptavidin | / | 0.482 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.481 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.481 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.481 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.480 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.479 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 1ads | NAP | Aldose reductase | 1.1.1.21 | 0.478 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.477 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.476 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.475 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.474 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.474 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.473 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.471 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.471 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.471 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 4mm4 | 8PR | Na(+):neurotransmitter symporter (Snf family) | / | 0.471 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.471 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.470 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.469 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.468 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.468 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.468 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.467 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.467 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.467 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.467 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.467 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.467 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.465 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.465 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 2bd0 | BIO | Sepiapterin reductase | / | 0.464 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.464 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.463 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.463 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.462 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.462 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.460 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.460 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.460 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.460 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.460 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.460 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.459 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.459 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.458 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.458 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.458 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.458 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.458 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 1jf0 | CZH | Obelin | / | 0.457 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.457 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.457 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.457 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.457 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.457 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.456 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.456 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.456 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.456 | |
| 4kmz | FOL | Folate receptor beta | / | 0.456 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.455 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.455 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.455 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.455 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.455 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.454 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.454 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.454 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1s07 | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.453 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.453 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.453 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.453 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.453 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2qry | TPS | Thiamine-binding periplasmic protein | / | 0.452 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.451 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1qv0 | CZH | Obelin | / | 0.450 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.450 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.450 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.450 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.450 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3keg | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.450 | |
| 3p9t | TCL | Repressor | / | 0.450 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.450 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.450 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.450 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.449 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.449 | |
| 2hzq | STR | Apolipoprotein D | / | 0.449 | |
| 2ipw | 2CL | Aldose reductase | 1.1.1.21 | 0.449 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.449 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.449 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.449 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4kxj | P34 | Nucleoprotein | / | 0.449 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.448 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.448 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.448 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.448 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.447 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.447 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.447 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.447 | |
| 4zas | TYD | CalS13 | / | 0.447 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 1lke | DOG | Bilin-binding protein | / | 0.446 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.446 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.446 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.446 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3mz9 | BHN | Nickel-binding periplasmic protein | / | 0.446 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.445 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.444 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.444 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.444 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.444 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.444 | |
| 1jf2 | CZH | Obelin | / | 0.443 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.443 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.443 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.442 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.442 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.442 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.442 | |
| 3k31 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3ocx | 2AM | Lipoprotein E | / | 0.442 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.442 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2acq | NAP | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2gh6 | CF3 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.441 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.441 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.441 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.440 | |
| 1e2l | TMC | Thymidine kinase | / | 0.440 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.440 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3h1q | ATP | Ethanolamine utilization protein EutJ | / | 0.440 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.440 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.440 | |
| 3qvi | K95 | HAP protein | / | 0.440 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.440 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.440 |