Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1uooGLY_PHE_ARG_PROProlyl endopeptidase3.4.21.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1uooGLY_PHE_ARG_PROProlyl endopeptidase3.4.21.261.000
1uopGLY_PHE_GLU_PROProlyl endopeptidase3.4.21.260.720
1uoqGLU_PHE_SER_PROProlyl endopeptidase3.4.21.260.622
3eq9X97Prolyl endopeptidase3.4.21.260.606
1e8mP0HProlyl endopeptidase3.4.21.260.504
4bcdTDVProlyl endopeptidase3.4.21.260.489
1xddAAYIntegrin alpha-L/0.444