sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uom | PTI | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1uom | PTI | Estrogen receptor | / | 1.000 | |
| 1yin | CM3 | Estrogen receptor | / | 0.636 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.610 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.609 | |
| 2pog | WST | Estrogen receptor | / | 0.592 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.590 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.586 | |
| 1err | RAL | Estrogen receptor | / | 0.574 | |
| 1nde | MON | Estrogen receptor beta | / | 0.526 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.525 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.524 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.513 | |
| 2jfa | RAL | Estrogen receptor | / | 0.502 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.498 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.487 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.485 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.478 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.470 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.458 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.457 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.454 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.452 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.451 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.447 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.447 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.446 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.446 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.443 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.443 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.443 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.442 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.442 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3aba | FLI | Cytochrome P450 | / | 0.441 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 |