sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1u5c | BIK | L-lactate dehydrogenase | 1.1.1.27 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1u5c | BIK | L-lactate dehydrogenase | 1.1.1.27 | 1.000 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.524 | |
| 4l4x | NDP | AmphI | / | 0.511 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.498 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.495 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.493 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.492 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.489 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.483 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.483 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.483 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.482 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.482 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.481 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.481 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.480 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.480 | |
| 2e15 | SAH | Diphthine synthase | / | 0.480 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.479 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.479 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.479 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.479 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.478 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.478 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.477 | |
| 2fto | TMP | Thymidylate synthase | / | 0.477 | |
| 2p2f | COA | Acetyl-coenzyme A synthetase | / | 0.477 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.477 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.475 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.475 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.474 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.474 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.474 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.473 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.473 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.473 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.472 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1e1l | NAP | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.471 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.471 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.471 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.471 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.470 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.470 | |
| 1w4a | APC | NTPase P4 | / | 0.470 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.470 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.470 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.469 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.469 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.468 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.468 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.468 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.467 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.467 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.467 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.467 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.467 | |
| 4y1b | NAP | AntE | / | 0.467 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.466 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.466 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.466 | |
| 2egl | SAH | Diphthine synthase | / | 0.466 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.466 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.465 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.465 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.465 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.465 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 1iy8 | NAD | Levodione reductase | / | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.464 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.463 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.463 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.463 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.462 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.462 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.462 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.462 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.462 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.462 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.461 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.461 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.461 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.461 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.461 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.461 | |
| 3mje | NDP | AmphB | / | 0.461 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.460 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.460 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.460 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.460 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.460 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.460 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.460 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.459 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.459 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.459 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.459 | |
| 3b9l | AZZ | Serum albumin | / | 0.459 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.459 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.459 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2dsg | SAH | Diphthine synthase | / | 0.458 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.458 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.458 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.458 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.458 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.458 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.458 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.458 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.457 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.457 | |
| 2xdr | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.457 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.457 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.457 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.456 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 2bxm | IMN | Serum albumin | / | 0.456 | |
| 2bxq | IMN | Serum albumin | / | 0.456 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.456 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.456 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.456 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.456 | |
| 3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.456 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.456 | |
| 4tlz | NAP | KtzI | / | 0.456 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.456 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.455 | |
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.455 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.455 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2o12 | FMN | Chorismate synthase | / | 0.455 | |
| 2r8o | T5X | Transketolase 1 | / | 0.455 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.455 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.455 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.455 | |
| 1cg0 | IMO | Adenylosuccinate synthetase | / | 0.454 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.454 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.454 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.454 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.454 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.454 | |
| 4pd6 | URI | Nucleoside permease | / | 0.454 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.454 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.454 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.453 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.453 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.453 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.453 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.453 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.453 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.453 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.453 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.453 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.452 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.452 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.452 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.452 | |
| 2xvv | 9DN | Serum albumin | / | 0.452 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.452 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.452 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.452 | |
| 4u7w | NDP | MxaA | / | 0.452 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.451 | |
| 2e16 | SAH | Diphthine synthase | / | 0.451 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.451 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.451 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.451 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.451 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.451 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.451 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.450 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 2avi | BTN | Avidin | / | 0.450 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.450 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.450 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.450 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.450 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.450 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.450 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.450 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.449 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.449 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.449 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.449 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.449 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.449 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.449 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.449 | |
| 4hxy | NDP | Plm1 | / | 0.449 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.449 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.448 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.448 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.448 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.448 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.448 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.448 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.448 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.448 | |
| 2p2x | SAH | Diphthine synthase | / | 0.448 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.448 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.448 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.448 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.448 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.448 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.448 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.447 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.447 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2pci | SAH | Diphthine synthase | / | 0.447 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.447 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.447 | |
| 3cp9 | C19 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 3eks | CY9 | Actin-5C | / | 0.447 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.447 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.446 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.446 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.446 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.446 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.446 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 2o98 | FSC | 14-3-3-like protein C | / | 0.446 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3gqo | APR | Non-structural polyprotein | / | 0.446 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.446 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.446 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.446 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.446 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.446 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.445 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.445 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.445 | |
| 1w48 | APC | NTPase P4 | / | 0.445 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.445 | |
| 2e8h | SAH | Diphthine synthase | / | 0.445 | |
| 2eld | SAH | Diphthine synthase | / | 0.445 | |
| 2emu | SAH | Diphthine synthase | / | 0.445 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2nvb | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.445 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.445 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.445 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.445 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.445 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.445 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.445 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.445 | |
| 4dtb | GMP | APH(2'')-Id | / | 0.445 | |
| 4eh7 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 4kwh | NAP | Reductase homolog | / | 0.445 | |
| 4xr9 | TMP | CalS8 | / | 0.445 | |
| 4ynp | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.445 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.444 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.444 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.444 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.444 | |
| 2dsi | SAH | Diphthine synthase | / | 0.444 | |
| 2fav | APR | Nonstructural polyprotein pp1a | / | 0.444 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.444 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.444 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 2yvg | NAD | Ferredoxin reductase | / | 0.444 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.444 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.444 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.444 | |
| 3rnn | RNN | Glutamate receptor 2 | / | 0.444 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.444 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.444 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4yb7 | ATP | ATP phosphoribosyltransferase | / | 0.444 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.443 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
| 1ht2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.443 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.443 | |
| 2eeq | SAH | Diphthine synthase | / | 0.443 | |
| 2i0a | MUI | Protease | / | 0.443 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.443 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.443 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.443 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.443 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.443 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.443 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.443 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.443 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.443 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.443 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.443 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.443 | |
| 4yp5 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.443 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.442 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.442 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.442 | |
| 2ejk | SAH | Diphthine synthase | / | 0.442 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.442 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 2owu | SAH | Diphthine synthase | / | 0.442 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2qe5 | 617 | Polyprotein | / | 0.442 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 2r9k | SGI | Beta-galactoside-specific lectin 1 | / | 0.442 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.442 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.442 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.442 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.442 | |
| 4blr | UTP | NTPase P4 | / | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.442 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.442 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.442 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.442 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.442 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.442 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.441 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.441 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.441 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.441 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.441 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.441 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.441 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.441 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.441 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.441 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.441 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.441 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.441 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.441 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.440 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 1sb8 | UD2 | WbpP | / | 0.440 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.440 | |
| 2ahc | VNL | Chorismate pyruvate-lyase | / | 0.440 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 2cvu | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.440 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.440 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.440 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.440 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.440 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.440 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.440 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.440 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.440 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.440 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.440 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.440 |