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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1trbFADThioredoxin reductase1.8.1.9

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1trbFADThioredoxin reductase1.8.1.91.000
1tdeFADThioredoxin reductase1.8.1.90.763
1cl0FADThioredoxin reductase1.8.1.90.686
1tdfFADThioredoxin reductase1.8.1.90.662
4jnqFDAThioredoxin reductase/0.492
3itjFADThioredoxin reductase 11.8.1.90.475
4ccrFADThioredoxin reductase/0.464
3ctyFADProbable thioredoxin reductase/0.450
4ccqFADThioredoxin reductase/0.449