Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.31.000
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.624
1lhwESMSex hormone-binding globulin/0.483
4emyPLPAminotransferase class I and II/0.475
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.464
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3i64DNA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.458
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
1wc0APCAdenylate cyclase/0.455
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.454
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
1wc1TATAdenylate cyclase/0.451
4ap1NAPSteroid monooxygenase/0.451
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4gncASORegucalcin3.1.1.170.450
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.450
2v7qADPATP synthase subunit beta, mitochondrial3.6.3.140.449
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2j9gANPBiotin carboxylase6.3.4.140.446
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.445
3cseN22Uncharacterized protein/0.445
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.444
1yqj6NPMitogen-activated protein kinase 14/0.444
2olcADPMethylthioribose kinase2.7.1.1000.443
4d9fDCSD-cysteine desulfhydrase/0.443
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1u3dFADCryptochrome-1/0.441
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.441
3eel53TUncharacterized protein/0.441
3ffkATPActin, alpha skeletal muscle/0.441
3qakUKAAdenosine receptor A2a/0.441
1kwsUGAGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3/0.440
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.440
1u3cFADCryptochrome-1/0.440
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.440
4kttSAMS-adenosylmethionine synthase isoform type-22.5.1.60.440