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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.7

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.71.000
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.736
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.576
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.574
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.540
2ebaFADPutative glutaryl-CoA dehydrogenase/0.519
3nf4FADAcyl-CoA dehydrogenase domain-containing protein/0.511
2z1qFADAcyl-CoA dehydrogenase/0.508
3r7kFDAProbable acyl CoA dehydrogenase/0.499
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.497
5jscFADPutative acyl-CoA dehydrogenase/0.496
3owaFADAcyl-CoA dehydrogenase/0.495
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.484
4irnFADAnaB/0.481
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.478
4iv6FDAIsovaleryl-CoA dehydrogenase/0.463
5af7FADAcyl-CoA dehydrogenase/0.452
2fonFADAcyl-coenzyme A oxidase/0.449
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.449