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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1t9c1SMAcetolactate synthase catalytic subunit, mitochondrial2.2.1.6

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1t9c1SMAcetolactate synthase catalytic subunit, mitochondrial2.2.1.61.000
1t9a1TBAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.559
1t9b1CSAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.523
1n0hCIEAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.521